NUR 509 Exam 1 questions with correct answers
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1.Adverse Reaction: Undesirable drug effects, severe and life threatening.
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2.Side Effects: Undesirable drug effect, is a mild reaction.
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3.First Pass: Ingest the drug orally, metabolized (usually by the liver or
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gut), the effect of the medication is reduced, and only part of the drug
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reaches the systemic circulation. The drugs will end up becoming less
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powerful.
4.first pass routes: Hepatic
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arterial Oral/entral |\
Portal venous |\
5.Half-Life: Time required for the body to eliminate 50% of a drug
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6.Approximately how many half lives does it take to remove a drug from the |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
body?: About 5 half-lives |\ |\ |\
7.Off Label Drugs: Drug is FDA approved for one use, but is being
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prescribed for a different purpose. |\ |\ |\ |\
8.FDA Approved Drugs: approved for a specific purpose
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9.Sublingual Route of Administration: absorbed more rapidly than enteric-
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coat- ed tablets. Sublingual medications are placed under the tongue
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and dissolve, allowing for quick absorption through the mucous
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membranes and entry into the bloodstream. |\ |\ |\ |\ |\
Bypass first-pass effect |\ |\
10.Enteral Route of Administration: enteric-coated tablets have a coating
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1 |\/ |\23
,|\ that prevents them from being broken down in the acidic environment
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of the stomach. They are not absorbed until they reach the higher pH of
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|\ the intestines, resulting in slower absorption.
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11.Intravenous Route of Administration: Medication administered via the |\ |\ |\ |\ |\ |\ |\ |\
veins, produces the most rapid drug response , can produce an almost
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immediate onset of action (bypasses the first past effect)
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12.Intramuscular Route of Administration: Requires a needle for |\ |\ |\ |\ |\ |\ |\ |
administration, medication is administered in the muscle, allows drug to |\ |\ |\ |\ |\ |\ |\ |\ |\ |
diffuse slowly into the many blood vessels within muscle tissue
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(bypasses the first pass effect). |\ |\ |\ |\
13.Subcutaneous Route of Administration: Medication administered under |\ |\ |\ |\ |\ |\
|\ the skin into the SUBCUTANEOUS tissue (bypasses the first pass effect)
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14.Intradermal Route of Administration: Medication is administered into |\ |\ |\ |\ |\ |\ |\
|\ the DERMIS of the skin (bypasses the first pass effect).
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15.Buccal Route of Administration: Medication is administered in the
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oral mu- cosa between the cheek and gum (bypasses first pass effect)
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16.Rectal Route of Administration: The delivery of medication via the
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rectum, good alternative when oral is not available (does NOT bypass
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first pass effect)
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2 |\/ |\23
, 17.Topical Route of Administration: Medication is applied directly on the |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
skin via ointment, gels, or creams (bypasses the first pass effect)
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18.Transdermal Route of Administration: Medication is administered via |\ |\ |\ |\ |\ |\ |\ |\
adhe- sive patches, provide constant rate of absorption (bypasses first
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pass effect) |\
19.Inhalation Route of Administration: Medication is directly delivered |\ |\ |\ |\ |\ |\ |\ |\
to the lungs for rapid absorption (bypasses first pass effect)
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20.potential for abuse or addiction |\ |\ |\ |\ |\
Schedule I Drug |\ |\
schedule 2 |\
schedule 3 |\
schedule 4 |\
schedule 5: 1: very high risk (not considered legitimate medical use):
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heroin, LSD, Marijuana |\ |\
2: high risk (have a strong potential for abuse or addiction but also have
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legitimate medical use): opium, morphine, cocaine |\ |\ |\ |\ |\
3: moderate risk (have less potential for abuse or addiction than
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schedule I or II drugs and have a useful medication purpose): Short-
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acting barbiturates and amphetamines |\ |\ |\
4: low risk: (a medically useful category of drugs that have less potential
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
for abuse or addiction than those of Schedules I, II, and III): diazepam
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
and chloral hydrate |\ |\
5: very low risk: (medically useful category of drugs that have less
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potential for abuse or addiction than those of Schedules I through IV):
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3 |\/ |\23
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1.Adverse Reaction: Undesirable drug effects, severe and life threatening.
|\ |\ |\ |\ |\ |\ |\ |\
2.Side Effects: Undesirable drug effect, is a mild reaction.
|\ |\ |\ |\ |\ |\ |\ |\
3.First Pass: Ingest the drug orally, metabolized (usually by the liver or
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
gut), the effect of the medication is reduced, and only part of the drug
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
reaches the systemic circulation. The drugs will end up becoming less
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
powerful.
4.first pass routes: Hepatic
|\ |\ |\ |\
arterial Oral/entral |\
Portal venous |\
5.Half-Life: Time required for the body to eliminate 50% of a drug
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
6.Approximately how many half lives does it take to remove a drug from the |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
body?: About 5 half-lives |\ |\ |\
7.Off Label Drugs: Drug is FDA approved for one use, but is being
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
prescribed for a different purpose. |\ |\ |\ |\
8.FDA Approved Drugs: approved for a specific purpose
|\ |\ |\ |\ |\ |\ |\
9.Sublingual Route of Administration: absorbed more rapidly than enteric-
|\ |\ |\ |\ |\ |\ |\ |\
coat- ed tablets. Sublingual medications are placed under the tongue
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
and dissolve, allowing for quick absorption through the mucous
|\ |\ |\ |\ |\ |\ |\ |\ |\
membranes and entry into the bloodstream. |\ |\ |\ |\ |\
Bypass first-pass effect |\ |\
10.Enteral Route of Administration: enteric-coated tablets have a coating
|\ |\ |\ |\ |\ |\ |\ |\
1 |\/ |\23
,|\ that prevents them from being broken down in the acidic environment
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
of the stomach. They are not absorbed until they reach the higher pH of
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
|\ the intestines, resulting in slower absorption.
|\ |\ |\ |\ |\
11.Intravenous Route of Administration: Medication administered via the |\ |\ |\ |\ |\ |\ |\ |\
veins, produces the most rapid drug response , can produce an almost
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
immediate onset of action (bypasses the first past effect)
|\ |\ |\ |\ |\ |\ |\ |\
12.Intramuscular Route of Administration: Requires a needle for |\ |\ |\ |\ |\ |\ |\ |
administration, medication is administered in the muscle, allows drug to |\ |\ |\ |\ |\ |\ |\ |\ |\ |
diffuse slowly into the many blood vessels within muscle tissue
|\ |\ |\ |\ |\ |\ |\ |\ |\ |
(bypasses the first pass effect). |\ |\ |\ |\
13.Subcutaneous Route of Administration: Medication administered under |\ |\ |\ |\ |\ |\
|\ the skin into the SUBCUTANEOUS tissue (bypasses the first pass effect)
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
14.Intradermal Route of Administration: Medication is administered into |\ |\ |\ |\ |\ |\ |\
|\ the DERMIS of the skin (bypasses the first pass effect).
|\ |\ |\ |\ |\ |\ |\ |\ |\
15.Buccal Route of Administration: Medication is administered in the
|\ |\ |\ |\ |\ |\ |\ |\ |\
oral mu- cosa between the cheek and gum (bypasses first pass effect)
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
16.Rectal Route of Administration: The delivery of medication via the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
rectum, good alternative when oral is not available (does NOT bypass
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
first pass effect)
|\ |\
2 |\/ |\23
, 17.Topical Route of Administration: Medication is applied directly on the |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
skin via ointment, gels, or creams (bypasses the first pass effect)
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
18.Transdermal Route of Administration: Medication is administered via |\ |\ |\ |\ |\ |\ |\ |\
adhe- sive patches, provide constant rate of absorption (bypasses first
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
pass effect) |\
19.Inhalation Route of Administration: Medication is directly delivered |\ |\ |\ |\ |\ |\ |\ |\
to the lungs for rapid absorption (bypasses first pass effect)
|\ |\ |\ |\ |\ |\ |\ |\ |\
20.potential for abuse or addiction |\ |\ |\ |\ |\
Schedule I Drug |\ |\
schedule 2 |\
schedule 3 |\
schedule 4 |\
schedule 5: 1: very high risk (not considered legitimate medical use):
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
heroin, LSD, Marijuana |\ |\
2: high risk (have a strong potential for abuse or addiction but also have
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
legitimate medical use): opium, morphine, cocaine |\ |\ |\ |\ |\
3: moderate risk (have less potential for abuse or addiction than
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
schedule I or II drugs and have a useful medication purpose): Short-
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
acting barbiturates and amphetamines |\ |\ |\
4: low risk: (a medically useful category of drugs that have less potential
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
for abuse or addiction than those of Schedules I, II, and III): diazepam
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
and chloral hydrate |\ |\
5: very low risk: (medically useful category of drugs that have less
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
potential for abuse or addiction than those of Schedules I through IV):
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
3 |\/ |\23