ANTIBIOTICS: AMINOGLYCOSIDES
Actual Questions and Answers
Expert-Verified Explanation
This Exam contains:
✪ 50 Questions and Answers
✪ Multiple-choice and True/False Format
✪ Expert-Verified Explanations
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1. What type of bacteria do aminoglycosides primarily target?
A. Gram-positive anaerobes
B. Gram-negative aerobic bacilli
C. Fungi
D. Parasites
Answer: B
EXPLANATION: Aminoglycosides are bactericidal antibiotics effective against serious
infections caused by gram-negative aerobic bacilli.
2. Which of the following is an aminoglycoside antibiotic?
A. Ciprofloxacin
B. Gentamicin
C. Amoxicillin
D. Erythromycin
Answer: B
EXPLANATION: Gentamicin is a commonly used aminoglycoside effective against various
gram-negative bacteria.
3. TRUE or FALSE: Aminoglycosides are bacteriostatic antibiotics.
Answer: FALSE
EXPLANATION: Aminoglycosides are bactericidal, meaning they kill bacteria directly.
4. What is the mechanism of action of bacteriostatic antibiotics?
, A. Destroy bacterial DNA
B. Prevent bacterial growth
C. Break down the cell wall
D. Stimulate immune response
Answer: B
EXPLANATION: Bacteriostatic antibiotics inhibit bacterial replication but do not directly kill
the bacteria.
5. What is the mechanism of action of bactericidal antibiotics?
A. Inhibit protein synthesis
B. Suppress immune function
C. Kill bacteria directly
D. Promote bacterial mutation
Answer: C
EXPLANATION: Bactericidal antibiotics directly destroy bacteria, which is essential in
treating severe infections.
6. Which bacteria is commonly treated with aminoglycosides?
A. Pseudomonas aeruginosa
B. Lactobacillus
C. Mycoplasma
D. Streptococcus pneumoniae
Answer: A
EXPLANATION: Aminoglycosides are highly effective against Pseudomonas aeruginosa, a
gram-negative pathogen.
7. Aminoglycosides are often used when:
A. Penicillin is the first-line treatment
B. The infection is mild
C. Penicillin is contraindicated
D. Topical therapy is preferred
Answer: C
EXPLANATION: Aminoglycosides are reserved for severe infections or when penicillin cannot
be used.