NURS 660: PSYCHOPHARM – CLOZAPINE, NMS & NEUROPATHWAYS 2025

NURS 660: PSYCHOPHARM – CLOZAPINE, NMS
& NEUROPATHWAYS
Actual Questions and Answers
Expert-Verified Explanation
This Exam contains:
✪ 50 Questions and Answers
✪ Multiple-choice and True/False Format
✪ Expert-Verified Explanations
✪ Verified with Trusted Textbooks



1. What is the minimum ANC level required to prescribe Clozapine in the
general population?

A. 500/μL
B. 1,000/μL
C. 1,500/μL
D. 2,000/μL
Answer: C
EXPLANATION: For the general population, Clozapine is only initiated when the ANC is
≥1,500/μL due to agranulocytosis risk.



2. What defines severe neutropenia?

A. <500/μL
B. 500–999/μL
C. 1,000–1,499/μL
D. ≥1,500/μL
Answer: A
EXPLANATION: Severe neutropenia is defined as an ANC less than 500/μL, increasing the
risk of life-threatening infections.



3. What ANC range indicates moderate neutropenia?

A. <500/μL
B. 500–999/μL
C. 1,000–1,499/μL
D. ≥1,500/μL
Answer: B

, EXPLANATION: This range is considered moderate and may necessitate changes in treatment
or increased monitoring.



4. What ANC level is considered mild neutropenia?

A. <500/μL
B. 500–999/μL
C. 1,000–1,499/μL
D. ≥1,500/μL
Answer: C
EXPLANATION: Mild neutropenia is defined as ANC between 1,000 and 1,499/μL and may
not require discontinuation of Clozapine.



5. For BEN patients, what is the acceptable starting ANC level for Clozapine?

A. ≥1,000/μL
B. ≥1,200/μL
C. ≥1,500/μL
D. ≥2,000/μL
Answer: A
EXPLANATION: In patients with Benign Ethnic Neutropenia (BEN), a lower ANC threshold
of 1,000/μL is acceptable.



6. Clozaril BEN patient: severe neutropenia is defined as?

A. <750/μL
B. <1,000/μL
C. <500/μL
D. <600/μL
Answer: C
EXPLANATION: Same as the general population, <500/μL ANC is considered severe in BEN
patients.



7. BEN neutropenia is defined within which ANC range?

A. 500–999/μL
B. 1,000–1,499/μL
C. <500/μL