NURS 600 quiz #3 modules 5-6
absorption SNRI's - ANS-food decreased the rate but not degree of absorption (food helps
decrease nausea)
Ankylosing Spondylitis - ANS-chronic inflammatory disease of joints of axial skeleton
pain and progressive stiffening of the spine
Benzo's - ANS-Valium
xanax
ativan
klonopin
Biologic DMARDS - ANS-TNF (tumor necrosis factor) Inhibitors:
etanercept
infliximab
adalimumab
golimumab
pegol certolizumab Etanercept.
Common DMARDS in Rheumatoid Arthritis - ANS-Methotrexate
usually the initial synthetic DMARD
7.5 mg orally once weekly, can increase to 15 mg orally once per week if tolerating meds with
no response.
Max dose: 20-25 mg/week
CREST constellation - ANS-Calcinosis, Raynaud's phenomenon, esophogeal dysmotility,
sclerodactlyly and telangiectasia
Depression Risk Factors - ANS-pre-existing mood disorder
Differential Diagnosis - ANS-occupational exposures
occlusive vascular disease
connective tissue disease
hematologic disorders
cold agglutinins
livedo reticularis
atherosclerosis, buergers disease, repetitive motion injury
Differential diagnosis for GAD - ANS-caffeine intoxication
stimulant/ etoh abuse
sedative
anxiolytic and hypotic withdrawal
panic disoders
phobias
OCD
Differential diagnosis for Panic Disorder - ANS-schizo
bipolar
depression
, pheochromocytoma
hyperthyroidsim
SE
cardiac arrhythmia
MI
abuse or withdrawal of substances
steroids
theophylline
Differential diagnosis for polymalgia rheumatic - ANS-giant cell arteritis.
Differential diagnosis PTSD - ANS-anxiety
Bipolar
Differential Dx for Depression - ANS-parkinsons, thyroid disorders, dementia, epilepsy, CVA
and tumors
Differential dx for Rheumatoid Arthritis - ANS-Psoriatic arthritis
seronegative spondyloarthritis
fibromyalgia
tendinitis
bursitis
viral infections
Differential DX for SLE - ANS-rheumatoid arthritis
mixed connective tissue disease
dermatomyositis
primary systemic vasculitides
fibromyalgia
endocarditis
lyme disease
MS
infections
non rheumatic disorders
Elimination SSRI's - ANS-half life is aprox 1 day
ranging from 20-30 hours.
fluoxeting takes 1-3 days. norfluoxetine: 4-16 days
fluvoxamine: 15 hrs.
escitalopram/lexapro: 27-32 hrs
General Anxiety Disorder - ANS-excessive worry over 6 month period of time about multiple
concerns that are difficult to control
General Anxiety Disorder Prevelance: - ANS-50-90% have co-morbid depression
Women > Men
5-6% of general population have GAD.
General Anxiety signs and symptoms - ANS-occurs more days than not associated with 3 or
more symptoms: easy fatigue, difficulty concentrating, muscle tension, sleep disturbance,
feelings of restlessness or hyperness. Hyperarousal and insomnia.
More disruptive than normal anxiety.
absorption SNRI's - ANS-food decreased the rate but not degree of absorption (food helps
decrease nausea)
Ankylosing Spondylitis - ANS-chronic inflammatory disease of joints of axial skeleton
pain and progressive stiffening of the spine
Benzo's - ANS-Valium
xanax
ativan
klonopin
Biologic DMARDS - ANS-TNF (tumor necrosis factor) Inhibitors:
etanercept
infliximab
adalimumab
golimumab
pegol certolizumab Etanercept.
Common DMARDS in Rheumatoid Arthritis - ANS-Methotrexate
usually the initial synthetic DMARD
7.5 mg orally once weekly, can increase to 15 mg orally once per week if tolerating meds with
no response.
Max dose: 20-25 mg/week
CREST constellation - ANS-Calcinosis, Raynaud's phenomenon, esophogeal dysmotility,
sclerodactlyly and telangiectasia
Depression Risk Factors - ANS-pre-existing mood disorder
Differential Diagnosis - ANS-occupational exposures
occlusive vascular disease
connective tissue disease
hematologic disorders
cold agglutinins
livedo reticularis
atherosclerosis, buergers disease, repetitive motion injury
Differential diagnosis for GAD - ANS-caffeine intoxication
stimulant/ etoh abuse
sedative
anxiolytic and hypotic withdrawal
panic disoders
phobias
OCD
Differential diagnosis for Panic Disorder - ANS-schizo
bipolar
depression
, pheochromocytoma
hyperthyroidsim
SE
cardiac arrhythmia
MI
abuse or withdrawal of substances
steroids
theophylline
Differential diagnosis for polymalgia rheumatic - ANS-giant cell arteritis.
Differential diagnosis PTSD - ANS-anxiety
Bipolar
Differential Dx for Depression - ANS-parkinsons, thyroid disorders, dementia, epilepsy, CVA
and tumors
Differential dx for Rheumatoid Arthritis - ANS-Psoriatic arthritis
seronegative spondyloarthritis
fibromyalgia
tendinitis
bursitis
viral infections
Differential DX for SLE - ANS-rheumatoid arthritis
mixed connective tissue disease
dermatomyositis
primary systemic vasculitides
fibromyalgia
endocarditis
lyme disease
MS
infections
non rheumatic disorders
Elimination SSRI's - ANS-half life is aprox 1 day
ranging from 20-30 hours.
fluoxeting takes 1-3 days. norfluoxetine: 4-16 days
fluvoxamine: 15 hrs.
escitalopram/lexapro: 27-32 hrs
General Anxiety Disorder - ANS-excessive worry over 6 month period of time about multiple
concerns that are difficult to control
General Anxiety Disorder Prevelance: - ANS-50-90% have co-morbid depression
Women > Men
5-6% of general population have GAD.
General Anxiety signs and symptoms - ANS-occurs more days than not associated with 3 or
more symptoms: easy fatigue, difficulty concentrating, muscle tension, sleep disturbance,
feelings of restlessness or hyperness. Hyperarousal and insomnia.
More disruptive than normal anxiety.
