ACCURACY IS GUARANTEED
A4M Practice Test Questions with Detailed
Verified Answers for Accuracy
Question: 1. Identify the true statement(s) concerning the role
of mitochondria in longevity, aging, and disease.
a. Decreased mitochondrial function results in increased
oxidative damage, caused by free radical formation combined
with a decrease in antioxidant enzyme system activity.
b. Maternal transmission of mitochondrial genomes is a factor
in differences in longevity between male and female organisms
(Drosophila model)
c. Alteration of the electron transport chain (ETC) promotes
survival and enhances longevity (C. elegans model).
d. a, b, c are true statements
e. Only a and b are true statements
Answer: 1. d
Question: For questions 2-4, match the property of the
therapeutic compound, with its correct name:
2. Shown to reduce all-cause mortality, as well as mortality
specifically due to cardiovascular disease and cancers, in men.
3. Shown to decrease the rate of telomere shortening.
4. Combined with calcium, shown to reduce mortality in the
elderly.
, ACCURACY IS GUARANTEED
a. Vitamin C
b. Vitamin D3
c. Vitamin E
d. CoEnzyme Q10
e. EPA/DHA
Answer: 2. a
3. e
4. b
Question: 5. Identify the true statements concerning the
role of the inflammation in aging and disease:
a. Inflammation is implicated as a key factor in arthritis,
asthma, allergies, diabetes, and heart disease.
b. The two major classes of inflammatory messengers are
prostaglandins and interleukins.
c. Activation of the protein complex nuclear factor kappa beta
in response to oxidative stress triggers as increase in pro-
inflammatory mediators, including IL-1, IL-6, IL-8, and TNF-
alpha.
d. Only a and b are true statements.
e. Only a and c are true statements.
Answer: 5. e
(the 2 major classes of inflammatory messengers are
prostaglandins and leukotrienes)
, ACCURACY IS GUARANTEED
Question: 6. Identify the true statements concerning
lifestyle (non-pharmacological) approaches in hypertensive
patients:
a. A large percentage of essential HTN patients may be
appropriate candidates, as long as blood pressure is evaluated
and clinical target organ damage, clinical CVD, DM, or
significant risk factors are not present at the time of diagnosis
and do not develop later.
b. Optimum nutrition, antioxidants, vitamins, and minerals are
counter indicated in patients taking antihypertensive drugs.
c. Non-pharmacological approaches to HTN are not valuable in
patients with normal BP.
d. A, b, c are true statements.
e. None of the above are true statements.
Answer: 6. a
b. ...may provide excellent adjunctive treatment...
c. ...should be encouraged...
Question: 7. Identify the true statements concerning the
role of increased oxidative stress in HTN:
a. Increases oxidative stress is due to increased generation of
ROS with a suppressed response to ROS.
b. Arachidonic acid metabolites do not contribute to increased
levels or ROS.
A4M Practice Test Questions with Detailed
Verified Answers for Accuracy
Question: 1. Identify the true statement(s) concerning the role
of mitochondria in longevity, aging, and disease.
a. Decreased mitochondrial function results in increased
oxidative damage, caused by free radical formation combined
with a decrease in antioxidant enzyme system activity.
b. Maternal transmission of mitochondrial genomes is a factor
in differences in longevity between male and female organisms
(Drosophila model)
c. Alteration of the electron transport chain (ETC) promotes
survival and enhances longevity (C. elegans model).
d. a, b, c are true statements
e. Only a and b are true statements
Answer: 1. d
Question: For questions 2-4, match the property of the
therapeutic compound, with its correct name:
2. Shown to reduce all-cause mortality, as well as mortality
specifically due to cardiovascular disease and cancers, in men.
3. Shown to decrease the rate of telomere shortening.
4. Combined with calcium, shown to reduce mortality in the
elderly.
, ACCURACY IS GUARANTEED
a. Vitamin C
b. Vitamin D3
c. Vitamin E
d. CoEnzyme Q10
e. EPA/DHA
Answer: 2. a
3. e
4. b
Question: 5. Identify the true statements concerning the
role of the inflammation in aging and disease:
a. Inflammation is implicated as a key factor in arthritis,
asthma, allergies, diabetes, and heart disease.
b. The two major classes of inflammatory messengers are
prostaglandins and interleukins.
c. Activation of the protein complex nuclear factor kappa beta
in response to oxidative stress triggers as increase in pro-
inflammatory mediators, including IL-1, IL-6, IL-8, and TNF-
alpha.
d. Only a and b are true statements.
e. Only a and c are true statements.
Answer: 5. e
(the 2 major classes of inflammatory messengers are
prostaglandins and leukotrienes)
, ACCURACY IS GUARANTEED
Question: 6. Identify the true statements concerning
lifestyle (non-pharmacological) approaches in hypertensive
patients:
a. A large percentage of essential HTN patients may be
appropriate candidates, as long as blood pressure is evaluated
and clinical target organ damage, clinical CVD, DM, or
significant risk factors are not present at the time of diagnosis
and do not develop later.
b. Optimum nutrition, antioxidants, vitamins, and minerals are
counter indicated in patients taking antihypertensive drugs.
c. Non-pharmacological approaches to HTN are not valuable in
patients with normal BP.
d. A, b, c are true statements.
e. None of the above are true statements.
Answer: 6. a
b. ...may provide excellent adjunctive treatment...
c. ...should be encouraged...
Question: 7. Identify the true statements concerning the
role of increased oxidative stress in HTN:
a. Increases oxidative stress is due to increased generation of
ROS with a suppressed response to ROS.
b. Arachidonic acid metabolites do not contribute to increased
levels or ROS.
