NURS 312 Midterm Pt2 (pharmacology) Questions With
Complete Solutions
buproprion mechanism of action Correct Answers Inhibits
dopamine reuptake by norepinepherine in brain areas where
dopamine transportors are absent
basically, inhibits reuptake of norepinepherine and dopamine in
the synapse
Common side effects of lithium Correct Answers Lithium is
mild in low doses
Thirst, metallic taste, urinary frequency, fine head and hand
tremors, drowsiness, diarrhea, weight gain and nausea
discontinuation phase Correct Answers Many drugs require a
tapered discontinuation. Basically, slowly reducing dosage while
monitoring closely for withdrawal symptoms and for the
reemergence of key symptoms, such as a drop in mood,
increased anxiety, sleep disturbance, thought disorder, or
decreased level of self-care
Want to make sure the patient gets off the medication ok and is
stable throughout the process
Extrapydramidal side effects found in antipsychotic meds (EPS)
Correct Answers Dystonias: prolonged contraction of muscles;
centrally acting anticholinergics (diphenhydramine, benztropine)
can be used for prophylaxis/tx. AKA abnormal posture and
muscle spasm
Akathisia: restlessness with anxiety; treated with
benzos/propranolol AKA involuntary movement disorder
, Parkinsonism: tx with anticholinergics or propranolol for tremor
Tardive dyskinesias: abnormal facial movements, higher risk in
elderly females; most stop drug and replace with SGA with low
EPS risk CHRONIC-- irregular repetetive involuntary
movements of the mouth, face, and tongue
Dyskinesias: abnormal movements; more common with
dopamine replacement in Parkinson's AKA impaired voluntary
movement
first generation antipsychotics
3 examples Correct Answers aka typical antipsychotics
haloperidol
chlorpromazine
thioridazine
first generation antipsychotics mechanism of action Correct
Answers serotonin-dopamine receptor antagonists
targets D2 dopamine receptors and 5HT2A serotonin receptors
relieves positive symptoms of schizophrenia *(ie hallucinations)
but does not relieve negative symptoms and can sometimes
make negative symptoms worse
how do amphetamines work? Correct Answers indirectly
stimulate the sympathetic nervous system, producing alertness,
awakeness, vasoconstriction, suppressed appetite and
hypothermia
Complete Solutions
buproprion mechanism of action Correct Answers Inhibits
dopamine reuptake by norepinepherine in brain areas where
dopamine transportors are absent
basically, inhibits reuptake of norepinepherine and dopamine in
the synapse
Common side effects of lithium Correct Answers Lithium is
mild in low doses
Thirst, metallic taste, urinary frequency, fine head and hand
tremors, drowsiness, diarrhea, weight gain and nausea
discontinuation phase Correct Answers Many drugs require a
tapered discontinuation. Basically, slowly reducing dosage while
monitoring closely for withdrawal symptoms and for the
reemergence of key symptoms, such as a drop in mood,
increased anxiety, sleep disturbance, thought disorder, or
decreased level of self-care
Want to make sure the patient gets off the medication ok and is
stable throughout the process
Extrapydramidal side effects found in antipsychotic meds (EPS)
Correct Answers Dystonias: prolonged contraction of muscles;
centrally acting anticholinergics (diphenhydramine, benztropine)
can be used for prophylaxis/tx. AKA abnormal posture and
muscle spasm
Akathisia: restlessness with anxiety; treated with
benzos/propranolol AKA involuntary movement disorder
, Parkinsonism: tx with anticholinergics or propranolol for tremor
Tardive dyskinesias: abnormal facial movements, higher risk in
elderly females; most stop drug and replace with SGA with low
EPS risk CHRONIC-- irregular repetetive involuntary
movements of the mouth, face, and tongue
Dyskinesias: abnormal movements; more common with
dopamine replacement in Parkinson's AKA impaired voluntary
movement
first generation antipsychotics
3 examples Correct Answers aka typical antipsychotics
haloperidol
chlorpromazine
thioridazine
first generation antipsychotics mechanism of action Correct
Answers serotonin-dopamine receptor antagonists
targets D2 dopamine receptors and 5HT2A serotonin receptors
relieves positive symptoms of schizophrenia *(ie hallucinations)
but does not relieve negative symptoms and can sometimes
make negative symptoms worse
how do amphetamines work? Correct Answers indirectly
stimulate the sympathetic nervous system, producing alertness,
awakeness, vasoconstriction, suppressed appetite and
hypothermia
