Menopause Midterm Practice Questions with 100% Correct Answers 2025

JW, a 53-year-old post-menopausal female, presents to the pharmacy with a new prescription for 17β- estradiol topical gel (EstroGel) for vasomotor symptom relief. Which of the following is the appropriate administration of 17β- estradiol topical gel (EstroGel)? A. Apply 1 pump depression once daily to one arm from wrist to shoulder B. Apply 1 pump depression once daily to one upper arm and shoulder area C. Apply 1 packet once daily to one upper thigh D. Apply 1 pouch once daily to each thigh and calf A. JW, a 53-year-old post-menopausal female, presents to the pharmacy with a new prescription for 17β- estradiol topical gel (EstroGel) for vasomotor symptom relief. Which statement should be included in the counseling for 17β- estradiol topical gel (EstroGel)? A. Apply gel after applying lotion, powder, or oil B. Washing hands after application is not necessary C. Allow gel to dry before dressing D. Massage or rub in gel after application C. CG is a 55-year-old post-menopausal woman seeking treatment for vasomotor symptoms. She has an intact uterus and a history of breast cancer. Which of the following patient data is an absolute contraindication to hormone replacement therapy? A. Former smoker B. Current treatment for type 2 diabetes C. History of breast cancer D. Family history of CHD C. CG is a 55-year-old post-menopausal woman seeking treatment for vasomotor symptoms. She has an intact uterus and a history of breast cancer. Which treatment is most appropriate for this patient? A. Micronized 17β- estradiol (Estrace) B. Venlafaxine (Effexor) C. Ospemifene (Osphena) D. Raloxifene (Evista) B. HC, a 52-year-old female, has been prescribed a continuous combined oral estrogen and progestogen product for vasomotor symptom relief related to menopause. She has read about the potential risks associated with HRT and would like to discuss these Menopause Menopause before filling the prescription. Which of the following strategies will help reduce the incidence of breast cancer? A. Limit duration of use to 5 years B. Use bioidentical HRT instead C. Use transdermal estrogen instead D. Use phytoestrogens instead A. HC, a 52-year-old female, has been prescribed a continuous combined oral estrogen and progestogen product for vasomotor symptom relief related to menopause. She has read about the potential risks associated with HRT and would like to discuss these before filling the prescription. Which of the following strategies will help reduce the incidence of VTE? A. Use transdermal estrogen instead B. Use black cohosh instead C. Use a product with medroxyprogesterone acetate B. HC, a 52-year-old female, has been prescribed a continuous combined oral estrogen and progestogen product for vasomotor symptom relief related to menopause. She has read about the potential risks associated with HRT and would like to discuss these before filling the prescription. Which of the following are vaginal tablets and are not taken orally and are administered vaginally? (Select ALL THAT APPLY) A. Imvexxy B. Duavee C. Vagifem D. Activella A. Chief complaint: Pain with sexual intercourse History of present illness: OR is a 46-year-old female presenting to the office today for an annual follow-up complaining of pain with sexual intercourse. She recently started taking Estroven Maximum Strength® but has noted little benefit. She denies other menopausal symptoms. Past medical history: Gestational DM with first pregnancy Surgical history: Hysterectomy (2016) secondary to fibroids, ovaries remain Social history: (-) for tobacco, EtOH, and illicit drugs Family history: (-) for breast and cervical cancer Current nonprescription medications: Centrum multivitamin one tablet daily, ibuprofen 200 mg one tablet as needed Current complementary and alternative medications: Estroven Maximum Strength® one caplet daily Menopause Menopause Which of the following is the most appropriate course of action for this patient? A. Oral estrogen only B. Combination oral estrogen and progestogen C. Intravaginal estrogen only D. Intravaginal estrogen and oral progestogen C. Chief complaint: Pain with sexual intercourse History of present illness: OR is a 46-year-old female presenting to the office today for an annual follow-up complaining of pain with sexual intercourse. She recently started taking Estroven Maximum Strength® but has noted little benefit. She denies other menopausal symptoms. Past medical history: Gestational DM with first pregnancy Surgical history: Hysterectomy (2016) secondary to fibroids, ovaries remain Social history: (-) for tobacco, EtOH, and illicit drugs Family history: (-) for breast and cervical cancer Current nonprescription medications: Centrum multivitamin one tablet daily, ibuprofen 200 mg one tablet as needed Current complementary and alternative medications: Estroven Maximum Strength® one caplet daily Which statement should be included in the counseling for estradiol hemihydrate vaginal tablet (Vagifem)? A. If the tablet is expelled, it may be rinsed off with warm water and reinserted B. May weaken latex found in condoms, diaphragms, or cervical caps C. Once the applicator is inserted, press the plunger until fully depressed D. Insert the tablet with the smaller end up for a depth of about two inches into the vaginal canal C. Chief complaint: Pain with sexual intercourse History of present illness: OR is a 46-year-old female presenting to the office today for an annual follow-up complaining of pain with sexual intercourse. She recently started taking Estroven Maximum Strength® but has noted little benefit. She denies other menopausal symptoms. Past medical history: Gestational DM with first pregnancy Surgical history: Hysterectomy (2016) secondary to fibroids, ovaries remain Social history: (-) for tobacco, EtOH, and illicit drugs Family history: (-) for breast and cervical cancer Current nonprescription medications: Centrum multivitamin one tablet daily, ibuprofen 200 mg one tablet as needed Current complementary and alternative medications: Estroven Maximum Strength® one caplet daily Which of the following would be the best advice regarding the use of Estroven Maximum Strength®? A. Continue Estroven Maximum Strength® as it is both safe and effective B. Continue Estroven Maximum Strength® as it safe, but inadequately studied C. Discontinue Estroven Maximum Strength® as it is ineffective and dangerous Menopause Menopause D. Discontinue Estroven Maximum Strength® as it lacks consistent evidence for safety and efficacy D. The most effective treatment to alleviate postmenopausal vasomotor symptoms (hot flashes and night sweats) is: A. Estrogen therapy. B. Selective estrogen-receptor modulators (SERMs). C. Testosterone therapy. D. Clonidine. A. Which of the following CYP450 isoenzymes metabolize