NURS 5463 (NURS5463) Test 5 |! |! |! |!
with precise answers
|! |! |!
Cirrhotic - Correct answer ✔liver has all the nodularities that cause the
|! |! |! |! |! |! |! |! |! |! |! |!
fibrosis
Cirrhosis - Correct answer ✔Abnormal LFT/Transaminitis (elevated LFT)
|! |! |! |! |! |! |!
Transaminitis - Correct answer ✔Elevated LFT |! |! |! |! |!
Acute or chronic liver disease - Correct answer ✔alanime transaminase
|! |! |! |! |! |! |! |! |! |!
(ALT) & Aspartate transaminase (AST), Alk Phos, Total Bilirubin, Direct
|! |! |! |! |! |! |! |! |! |!
Bilirubin, occurs in acute or chronic liver disease
|! |! |! |! |! |! |!
H&P for transaminitis - Correct answer ✔Helps to determine acute or
|! |! |! |! |! |! |! |! |! |! |!
chronic
Cirrhosis risk factors - Correct answer ✔IV drug use: Intranasal cocaine - the
|! |! |! |! |! |! |! |! |! |! |! |! |!
straws used when using intranasal cocaine causes breakdown in the nasal
|! |! |! |! |! |! |! |! |! |! |!
mucosa and that is how the viruses are transmitted, Needle sticks such in
|! |! |! |! |! |! |! |! |! |! |! |! |!
health care providers,
|! |!
HD patients - Correct answer ✔higher risk for contracting Hep B
|! |! |! |! |! |! |! |! |! |!
,Blood transfusion prior to 1991/1992 - Correct answer ✔pt could have
|! |! |! |! |! |! |! |! |! |! |!
contracted hep C before we knew to test for hep C
|! |! |! |! |! |! |! |! |! |!
Acute liver Failure Work up for Transaminitis - Correct answer ✔Viral
|! |! |! |! |! |! |! |! |! |! |!
Serologies (hep ABC), Autoimmune marker |! |! |! |!
Doppler US of liver want to look at the plumbing of the liver - Correct
|! |! |! |! |! |! |! |! |! |! |! |! |! |! |!
answer ✔hepatic veins and arteries
|! |! |! |!
MRI/MRCP - Correct answer ✔MR that focuses on the biliary tree and bile
|! |! |! |! |! |! |! |! |! |! |! |! |!
ducts, intrahepatic and extrahepatic ductal dilatation) Liver biopsy
|! |! |! |! |! |! |!
↑↑Aminotransferases (AST/ALT), +/- ↑ in Bilirubin, AK - Correct answer |! |! |! |! |! |! |! |! |! |!
✔Labs for Severe viral Hepatitis, Acetaminophen overdose, Ischemia,
|! |! |! |! |! |! |! |!
Wilson's disease, AIH; related to liver injury
|! |! |! |! |! |!
↑↑ Alkaline Phosphate, GGT, Bilirubin, +/- ↑ AST/ALT - Correct answer
|! |! |! |! |! |! |! |! |! |! |!
✔Labs for Biliary Obstruction, Choledocholithiasis, cholangiocarcinoma,
|! |! |! |! |! |!
pancreatic cancer, Intrahepatic cholestatis, Sepsis, PBC, Sex Horm., Biliary
|! |! |! |! |! |! |! |! |!
Epitheleal Damage; related to cholestatic injury
|! |! |! |! |!
Synthetic Function/Hepatic Function - Correct answer ✔how well is the liver
|! |! |! |! |! |! |! |! |! |!
working. INR, albumin (low albumin can represent chronic problems were
|! |! |! |! |! |! |! |! |! |! |!
as normal albumin problem is more acute), and total bilirubin
|! |! |! |! |! |! |! |! |!
,Hepatitis A, B, C Full serologic work up - Correct answer ✔Hep A IgM, Hep
|! |! |! |! |! |! |! |! |! |! |! |! |! |! |!
A total, Hep B surface antigen, Hep B surface antibody, Hep B core IgM, Hep
|! |! |! |! |! |! |! |! |! |! |! |! |! |! |!
B core total, and Hep C antibody. ANA, smooth muscle antibody (one or both
|! |! |! |! |! |! |! |! |! |! |! |! |!
can be elevated), Serum gamma globulins - can also be elevated, ANCA can
|! |! |! |! |! |! |! |! |! |! |! |! |! |!
be present, Anti-LKM1
|! |!
Hepatotoxic Drugs - Correct answer ✔Dilantin, Tylenol Accutane,
|! |! |! |! |! |! |! |!
Allopurinol, HAART, Statin, Methotrexate, INH (TB med), Risperidone,
|! |! |! |! |! |! |! |!
Zoloft, Valproic acid, psych meds, Estrogen, Augmentin, Sulfonamides
|! |! |! |! |! |! |!
Hepatotoxic Herbs - Correct answer ✔Noni juice, Chinese remedies & teas,
|! |! |! |! |! |! |! |! |! |! |!
Valerian, Mistletoe, Herbalife. |! |!
Hepatoxic Toxins - Correct answer ✔, , ETOH |! |! |! |! |! |! |!
Acute Liver injury AST/ALT ratio - Correct answer ✔2:1
|! |! |! |! |! |! |! |!
Acute Liver Injury abdomen ultrasound shows - Correct answer ✔steatosis,
|! |! |! |! |! |! |! |! |! |!
cirrhosis, or focal lesions, Result in alcoholic fatty liver disease
|! |! |! |! |! |! |! |! |!
Vascular Liver Disorders - Correct answer ✔Budd-Chiari Syndrome,
|! |! |! |! |! |! |! |!
Obstruction of hepatic vein (thrombus) |! |! |! |!
Vascular Liver Disorders Work up - Correct answer ✔US of liver &
|! |! |! |! |! |! |! |! |! |! |! |!
hypercoagulable work up |! |!
, Congestive Hepatopathy - Correct answer ✔Related to right sided HF; Echo
|! |! |! |! |! |! |! |! |! |! |!
to look at heart function
|! |! |! |!
Causes of Congestive Hepatopathy - Correct answer ✔Ischemic (hypotension)
|! |! |! |! |! |! |! |!
(e.g. OR prolonged hypotensive) Shocked liver (suspected from prolonged
|! |! |! |! |! |! |! |! |! |!
Hypotensive Episodes) |!
Alpha 1 antitrypsin - Correct answer ✔inherited disorder (rare) that affect
|! |! |! |! |! |! |! |! |! |! |!
lung, liver and skin.
|! |! |!
Alpha antitrypsin Labs - Correct answer ✔antitrypsin phenotype (send out to
|! |! |! |! |! |! |! |! |! |! |!
Mayo Clinic) |!
Primary Biliary Cirrhosis - Correct answer ✔Autoimmune disorder that affect
|! |! |! |! |! |! |! |! |!
middle aged women
|! |! |!
Primary Biliary Cirrhosis Labs - Correct answer ✔Alk phos or Total bilirubin,
|! |! |! |! |! |! |! |! |! |! |!
anti-mitochondrial antibody and IgM (all
|! |! |! |! |!
elevated) - Correct answer ✔ |! |! |! |!
Hemochromatosis - Correct answer ✔Autosomal recessive disease; |! |! |! |! |! |! |!
Caucasians & Western European decent, resulting in very elevated Iron
|! |! |! |! |! |! |! |! |! |!
saturation or ferritin |! |!
with precise answers
|! |! |!
Cirrhotic - Correct answer ✔liver has all the nodularities that cause the
|! |! |! |! |! |! |! |! |! |! |! |!
fibrosis
Cirrhosis - Correct answer ✔Abnormal LFT/Transaminitis (elevated LFT)
|! |! |! |! |! |! |!
Transaminitis - Correct answer ✔Elevated LFT |! |! |! |! |!
Acute or chronic liver disease - Correct answer ✔alanime transaminase
|! |! |! |! |! |! |! |! |! |!
(ALT) & Aspartate transaminase (AST), Alk Phos, Total Bilirubin, Direct
|! |! |! |! |! |! |! |! |! |!
Bilirubin, occurs in acute or chronic liver disease
|! |! |! |! |! |! |!
H&P for transaminitis - Correct answer ✔Helps to determine acute or
|! |! |! |! |! |! |! |! |! |! |!
chronic
Cirrhosis risk factors - Correct answer ✔IV drug use: Intranasal cocaine - the
|! |! |! |! |! |! |! |! |! |! |! |! |!
straws used when using intranasal cocaine causes breakdown in the nasal
|! |! |! |! |! |! |! |! |! |! |!
mucosa and that is how the viruses are transmitted, Needle sticks such in
|! |! |! |! |! |! |! |! |! |! |! |! |!
health care providers,
|! |!
HD patients - Correct answer ✔higher risk for contracting Hep B
|! |! |! |! |! |! |! |! |! |!
,Blood transfusion prior to 1991/1992 - Correct answer ✔pt could have
|! |! |! |! |! |! |! |! |! |! |!
contracted hep C before we knew to test for hep C
|! |! |! |! |! |! |! |! |! |!
Acute liver Failure Work up for Transaminitis - Correct answer ✔Viral
|! |! |! |! |! |! |! |! |! |! |!
Serologies (hep ABC), Autoimmune marker |! |! |! |!
Doppler US of liver want to look at the plumbing of the liver - Correct
|! |! |! |! |! |! |! |! |! |! |! |! |! |! |!
answer ✔hepatic veins and arteries
|! |! |! |!
MRI/MRCP - Correct answer ✔MR that focuses on the biliary tree and bile
|! |! |! |! |! |! |! |! |! |! |! |! |!
ducts, intrahepatic and extrahepatic ductal dilatation) Liver biopsy
|! |! |! |! |! |! |!
↑↑Aminotransferases (AST/ALT), +/- ↑ in Bilirubin, AK - Correct answer |! |! |! |! |! |! |! |! |! |!
✔Labs for Severe viral Hepatitis, Acetaminophen overdose, Ischemia,
|! |! |! |! |! |! |! |!
Wilson's disease, AIH; related to liver injury
|! |! |! |! |! |!
↑↑ Alkaline Phosphate, GGT, Bilirubin, +/- ↑ AST/ALT - Correct answer
|! |! |! |! |! |! |! |! |! |! |!
✔Labs for Biliary Obstruction, Choledocholithiasis, cholangiocarcinoma,
|! |! |! |! |! |!
pancreatic cancer, Intrahepatic cholestatis, Sepsis, PBC, Sex Horm., Biliary
|! |! |! |! |! |! |! |! |!
Epitheleal Damage; related to cholestatic injury
|! |! |! |! |!
Synthetic Function/Hepatic Function - Correct answer ✔how well is the liver
|! |! |! |! |! |! |! |! |! |!
working. INR, albumin (low albumin can represent chronic problems were
|! |! |! |! |! |! |! |! |! |! |!
as normal albumin problem is more acute), and total bilirubin
|! |! |! |! |! |! |! |! |!
,Hepatitis A, B, C Full serologic work up - Correct answer ✔Hep A IgM, Hep
|! |! |! |! |! |! |! |! |! |! |! |! |! |! |!
A total, Hep B surface antigen, Hep B surface antibody, Hep B core IgM, Hep
|! |! |! |! |! |! |! |! |! |! |! |! |! |! |!
B core total, and Hep C antibody. ANA, smooth muscle antibody (one or both
|! |! |! |! |! |! |! |! |! |! |! |! |!
can be elevated), Serum gamma globulins - can also be elevated, ANCA can
|! |! |! |! |! |! |! |! |! |! |! |! |! |!
be present, Anti-LKM1
|! |!
Hepatotoxic Drugs - Correct answer ✔Dilantin, Tylenol Accutane,
|! |! |! |! |! |! |! |!
Allopurinol, HAART, Statin, Methotrexate, INH (TB med), Risperidone,
|! |! |! |! |! |! |! |!
Zoloft, Valproic acid, psych meds, Estrogen, Augmentin, Sulfonamides
|! |! |! |! |! |! |!
Hepatotoxic Herbs - Correct answer ✔Noni juice, Chinese remedies & teas,
|! |! |! |! |! |! |! |! |! |! |!
Valerian, Mistletoe, Herbalife. |! |!
Hepatoxic Toxins - Correct answer ✔, , ETOH |! |! |! |! |! |! |!
Acute Liver injury AST/ALT ratio - Correct answer ✔2:1
|! |! |! |! |! |! |! |!
Acute Liver Injury abdomen ultrasound shows - Correct answer ✔steatosis,
|! |! |! |! |! |! |! |! |! |!
cirrhosis, or focal lesions, Result in alcoholic fatty liver disease
|! |! |! |! |! |! |! |! |!
Vascular Liver Disorders - Correct answer ✔Budd-Chiari Syndrome,
|! |! |! |! |! |! |! |!
Obstruction of hepatic vein (thrombus) |! |! |! |!
Vascular Liver Disorders Work up - Correct answer ✔US of liver &
|! |! |! |! |! |! |! |! |! |! |! |!
hypercoagulable work up |! |!
, Congestive Hepatopathy - Correct answer ✔Related to right sided HF; Echo
|! |! |! |! |! |! |! |! |! |! |!
to look at heart function
|! |! |! |!
Causes of Congestive Hepatopathy - Correct answer ✔Ischemic (hypotension)
|! |! |! |! |! |! |! |!
(e.g. OR prolonged hypotensive) Shocked liver (suspected from prolonged
|! |! |! |! |! |! |! |! |! |!
Hypotensive Episodes) |!
Alpha 1 antitrypsin - Correct answer ✔inherited disorder (rare) that affect
|! |! |! |! |! |! |! |! |! |! |!
lung, liver and skin.
|! |! |!
Alpha antitrypsin Labs - Correct answer ✔antitrypsin phenotype (send out to
|! |! |! |! |! |! |! |! |! |! |!
Mayo Clinic) |!
Primary Biliary Cirrhosis - Correct answer ✔Autoimmune disorder that affect
|! |! |! |! |! |! |! |! |!
middle aged women
|! |! |!
Primary Biliary Cirrhosis Labs - Correct answer ✔Alk phos or Total bilirubin,
|! |! |! |! |! |! |! |! |! |! |!
anti-mitochondrial antibody and IgM (all
|! |! |! |! |!
elevated) - Correct answer ✔ |! |! |! |!
Hemochromatosis - Correct answer ✔Autosomal recessive disease; |! |! |! |! |! |! |!
Caucasians & Western European decent, resulting in very elevated Iron
|! |! |! |! |! |! |! |! |! |!
saturation or ferritin |! |!