ONS Chemotherapy Immunotherapy Certificate Questions and Correct Answers

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ONS Chemotherapy Immunotherapy
Certificate Questions and Correct
Answers

Question: Define neoadjuvant therapy
Answer: Treatment is given prior to surgery to shrink the tumor


Question: Define adjuvant therapy
Answer: Additional cancer treatment given after the primary treatment to
lower the risk that the cancer reoccur


Question: 3 subcategories of alkylating agents:
Answer: 1. Nitrogen mustards
2. Platinum-based agents (do not possess an alkyl group but still termed
alkylating agents as they work similarly)
3. Nitrosoureas


Question: Common alkylating agents:
Answer: Cyclophosphamide (Cytoxan)
Ifosfamide (Ifex)
Bendamustine (Treanda)


Question: Common platinum-based agents:
Answer: Cisplatin (Platinol)
Carboplatin (Paraplatin)


Question: What is unique about nitrosoureas agents?
Answer: Able to cross the blood-brain barrier; can be effective in treating
some brain tumors




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Question: Common nitrosoureas agents:
Answer: Carmustine (BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)


Question: Hypersensitivity can occur with late doses of:
Answer: Carboplatin


Question: These agents are typically categorized as highly emetogenic:
Answer: 1. Alkylating agents
2. Nitrosoureas


Question: Pre-administration labs for alkylating agents and
nitrosoureas:
Answer: BUN
Creatinine
CBC w/ diff


Question: What is the medication Mesna used for?
Answer: Bladder protectant with administration of cyclophosphamide or
ifosfamide


Question: Instruct pts receiving ________ to avoid exposure to cold air
and consuming cold fluids for 3-4 days following treatment
Answer: Oxaliplatin


Question: How do antimetabolites function?
Answer: By blocking DNA and RNA growth by interfering with enzymes
needed for normal cell metabolism


Question: Antimetabolites work in the ___ phase.
Answer: S



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Question: Common side effects of antimetabolites:
Answer: Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome


Question: Common antimetabolite drugs:
Answer: Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate


Question: The institute for Safe Medication Practices recommends what
route of administration for vincristine?
Answer: IV piggyback via gravity


Question: Anthracycline antitumor abx work by:
Answer: Interfering with enzymes necessary for DNA to replicate in ALL
phases of the cell cycle


Question: The two major classifications of antitumor antibiotics are:
Answer: Anthracyclines
Non-anthracyclines


Question: Common anthracycline antitumor abx:
Answer: Daunorubicin
Doxorubicin
Epirubicin
Idarubicin


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