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characteristics that describe a specialty drug - ANSWER - high cost\n-
complex treatment\n- special handling, storage, delivery\n-
limited/exclusive availability for distributions\n- treat rare diseases\n-
treat long-term/severe side effects or increased fatality diseases\n- payer
may define what they consider to be a specialty med\n- biologically
derived and available on injections, infusion, or oral form
common additional req that SPECIALITY PHARMACY must offer -
ANSWER - coordinate care and facilitate drug access\n- facilitate mail
order delivery logistics\n- work w. health insurances to determine
coverage\n- investigate pt assistance programs for those w/o insurance\n-
case management- disease state management\n- data management\n- call
center development
process pt would need to follow in order to obtain a specialty med -
ANSWER - Rx would be send to specialty pharm\n- Specialty pharm
would be responsible in making sure patient receives medication, knows
the risks, is able to afford it, take responsibly.\n- connected with a case
manager on a monthly basis to make sure there are no issues with the
medications\n- happens every month prior to sending out the next
month's worth of medications to minimize waste, ensure safety, and
assess for efficacy
most chronic disease states that are treated with specialty medications -
ANSWER - oncology\n- multiple sclerosis\n- rheumatoid arthritis\n-
Crohn's disease\n- hepatitis C\n- HIV/AIDs
description of the basic disease process including common symptoms of
following disease states: Rheumatoid arthritis, Multiple Sclerosis, Crohn's
disease, Hepatitis C, and HIV - ANSWER - RA- chronic autoimmune
disease causing inflammation and tissure damage to cell; pain, stiffness,
reduced ROM\n\n- MS- disrupts flow of info within brain and btw brain
and body; fatigue, difficulty walking, stiffness, weakness, pain,
depression\n\n- Crohn's Disease- inflammatory bowel disease; abdominal
, pain, fatigue, weight loss, malnutrition\n\n- Hep C- viral infection
causing liver inflammation that can lead to liver disease; bleeding and
bruising easily, dark urine, fatigue, confusion\n\n- HIV - retrovirus that
attacks immune syst.; destroy CD4 cells (T cells) and pt no longer able to
fight off bateria
Define the following terms related to the immune system: Humoral
immunity, cell mediated immunity, Antibodies, T-cells and cytokines. -
ANSWER - Humural immunity- immune response mediated by B cells,
production of antibodies that target specific agents\n\n- cell mediated
immunity - in collaboration with humoral and its mediated by T- cell\n\n-
antibodies- molecules that have the ability to bind to and inactivate
antigen molecules\n\n- T-cells- T lymphocytes that act through the
production of cytokines\n\nCytokines - non-antibody products
Describe the impact on the immune system of the more common
immunomodulating drugs such as: interferons, anti-TNF monoclonal
antibodies, interleukins (specifically IL-2). - ANSWER - Interferons:
have three different effects on the immune system and can restore
function if it's not working properly\n\n- IL-2: restores immune response
by binding to receptor sites on T-Cells\n\n- anti-TFN monoclonal
antibodies: designated to attack certain aspects of immune system
List two of the new hepatitis C treatment options and describe how they
improve previous treatment options. - ANSWER Harvoni and Viekira
Pak.\n\n- targets the hepatitis C virus specifically\n- chance for a cure is
now close to 96%\n- treatment is not chronic\n- treatment: 8-12 weeks
long
Explain what the HIV virus does once it enters the body. - ANSWER
HIV is a retrovirus. Takes over the process of DNA transcription
Explain why it is not recommended to treat HIV with only one
medication. - ANSWER monotherapy cant counter development of of
drug resistance and missed dose can quickly lead to a poor outcome
List the primary antiretroviral classes covered in this module and provide
a brief description at how they target the HIV virus. - ANSWER - NRTIs-
incoorperate self into DNA and inhibit reverse transcriptase\n\n-
NNRITS- bind to enzyme and reverse transcriptase\n\n- Protase
Inhibitors- inhibits protase\n\n- intergrase inhibitor- blocks integrase
enzyme\n\n- fusion inhibitor- prevents complete fusion of HIV to host
cell