ATI Pharmacology RN Exam Questions
And Answers
/. Digoxin (lanoxin) SE - Answer-blurred/double vision
/.Guaifenesin SE - Answer-can cause drowsiness
/.Estrogen (premarin) SE - Answer-↑ risk of Thromboembolism with s/s: SOB, severe
headache, vomiting, sudden acute pain in the calves, legs, chest, abdomen.
/.Doxepin (Sinequan) [anticholinergic] SE - Answer-urinary retension, constipation,
drying of nasal/oral secretons, ↑HR
/.Albuterol (Proventil) [sympathomimetic/ adrenergic beta-2 agonist] Contraindicated -
Answer-with MAOIs (can↑ action of albuterol and → HTN crisis); β-blockers can inhibit
the therapeutic effects Use: invert canister, shake before use, rinse mouth after use,
w/new inhaler perform test spray
/.Levothryoxine (T4) Indication - Answer-hypothyroidism RT dysfxn of hypothalamus,
pituitary, or thyroid gland
/.Cephalosporins (Keflex) - Answer-allergy to cephalosporins is considered a precaution
for taking penicillins
/.Phenobarbital [Barbiturates]; interventions for anticonvulsant therapy - Answer-assess
for resp. depression, excess sedation from toxic effects, IV at < 50mg/min, avoid
extravasation (alkaline→skin damage)
/.Sumatriptan (Imitrex) use - Answer-when migraine symptoms appear and again in 1 hr
if symptoms persist
/.Route—fastest/most effective - Answer-intravenous
/.Narcan [opioid antagonist] - Answer-therapeutic action: improvement of respiratory
rate
/.Baclofen (Lioresal) Therapeutic action - Answer-↓ frequency & severity of muscle
spasms
/.Erythromycin (Erythrocin) [macrolide] SE - Answer-liver toxicity
/.What do need to avoid when taking Spironolactone (Aldactone) [K sparing diuretic] -
Answer-foods w/ ↑ K such as salt substitutes
, /.Chloroquine phosphate (Aralen): Indication - Answer-malaria prevention; Use: take
weekly starting 1 week before departure and continued for 4 weeks after return.
/.Heparin (anticoagulant) Use - Answer-w/alteplase for acute MI
/.Warfarin (Coumadin) Use - Answer-long-term prophylaxis of thrombosis [antidote—Vit
K]
/.Clopidogrel (Plavix) Use - Answer-reduce long-term risk of clotting w/ atherosclerosis
and recent MI of CVA
/.Alteplase (Activase) [antithrombolytic] Use - Answer-Acute MI/CVA (has short half-life)
/.Methylphenidate (Concerta) Use - Answer-marcolepsy Precaution: avoid caffeine use
/.Testosterone IM use - Answer-If use to correct delayed puberty→assess bone
maturation with bi-annual x-rays of hand and wrist; monitor liver function (can ↑
hypoglycemia, potentiate sleep apnea, exacerbate heart failure due to fluid retention.
/.Diphenoxylate & Atropine (Lomotil) Caution - Answer-With Renal impairment ↓
elimination of atropine → ↑ anticholinergic effects of atropine like confusion
/.Loperamide (Imodium) use - Answer-anti-diarrheal (poorly absorbed from GI tract;
difficulty crossing the blood-brain barrier)
/.Methylcellulose (Citrucel) use - Answer-bulk-forming agent with minimal Side Effects
(SE)
/.Psyllium (Metamucil) use - Answer-bulk-forming agent with minimal Side Effects (SE)
/.Acetazolamide (Diamox) [diuretic] indication - Answer-edema, epilepsy, acute
mountain sickness, glaucoma (↓ intraocular pressure by ↓ amount of aqueous humor in
the eye) Contra: allergy to sulfonamides
/.Metoprolol (Lopressor) [β-blocker] use and side effects - Answer-Hold dose for
dyspnea (sign of exacerbation of CHF) Propanolol (Inderal) Use. Dysrhythmia, HTN,
angina; SE: bronchoconstriction/bronchospasm; can block glyconeogenesis
/.Norgestrel (Ovrette) use and contraindication - Answer-contraception; SE: excess
progestin →weight gain from ↑ appetite; deficiency of progestin: late breakthrough
bleeding, amenorrhea; excess estrogen → edema Medroxyprogesterone (Provera);
Contra: smoking/tobacco products; Risks: Thromboembolism & Cardiovascular
complications; Interventions: use additional contraceptive measures w/antibiotic therapy
/.IM injection site - Answer-locate dorsogluteal site
And Answers
/. Digoxin (lanoxin) SE - Answer-blurred/double vision
/.Guaifenesin SE - Answer-can cause drowsiness
/.Estrogen (premarin) SE - Answer-↑ risk of Thromboembolism with s/s: SOB, severe
headache, vomiting, sudden acute pain in the calves, legs, chest, abdomen.
/.Doxepin (Sinequan) [anticholinergic] SE - Answer-urinary retension, constipation,
drying of nasal/oral secretons, ↑HR
/.Albuterol (Proventil) [sympathomimetic/ adrenergic beta-2 agonist] Contraindicated -
Answer-with MAOIs (can↑ action of albuterol and → HTN crisis); β-blockers can inhibit
the therapeutic effects Use: invert canister, shake before use, rinse mouth after use,
w/new inhaler perform test spray
/.Levothryoxine (T4) Indication - Answer-hypothyroidism RT dysfxn of hypothalamus,
pituitary, or thyroid gland
/.Cephalosporins (Keflex) - Answer-allergy to cephalosporins is considered a precaution
for taking penicillins
/.Phenobarbital [Barbiturates]; interventions for anticonvulsant therapy - Answer-assess
for resp. depression, excess sedation from toxic effects, IV at < 50mg/min, avoid
extravasation (alkaline→skin damage)
/.Sumatriptan (Imitrex) use - Answer-when migraine symptoms appear and again in 1 hr
if symptoms persist
/.Route—fastest/most effective - Answer-intravenous
/.Narcan [opioid antagonist] - Answer-therapeutic action: improvement of respiratory
rate
/.Baclofen (Lioresal) Therapeutic action - Answer-↓ frequency & severity of muscle
spasms
/.Erythromycin (Erythrocin) [macrolide] SE - Answer-liver toxicity
/.What do need to avoid when taking Spironolactone (Aldactone) [K sparing diuretic] -
Answer-foods w/ ↑ K such as salt substitutes
, /.Chloroquine phosphate (Aralen): Indication - Answer-malaria prevention; Use: take
weekly starting 1 week before departure and continued for 4 weeks after return.
/.Heparin (anticoagulant) Use - Answer-w/alteplase for acute MI
/.Warfarin (Coumadin) Use - Answer-long-term prophylaxis of thrombosis [antidote—Vit
K]
/.Clopidogrel (Plavix) Use - Answer-reduce long-term risk of clotting w/ atherosclerosis
and recent MI of CVA
/.Alteplase (Activase) [antithrombolytic] Use - Answer-Acute MI/CVA (has short half-life)
/.Methylphenidate (Concerta) Use - Answer-marcolepsy Precaution: avoid caffeine use
/.Testosterone IM use - Answer-If use to correct delayed puberty→assess bone
maturation with bi-annual x-rays of hand and wrist; monitor liver function (can ↑
hypoglycemia, potentiate sleep apnea, exacerbate heart failure due to fluid retention.
/.Diphenoxylate & Atropine (Lomotil) Caution - Answer-With Renal impairment ↓
elimination of atropine → ↑ anticholinergic effects of atropine like confusion
/.Loperamide (Imodium) use - Answer-anti-diarrheal (poorly absorbed from GI tract;
difficulty crossing the blood-brain barrier)
/.Methylcellulose (Citrucel) use - Answer-bulk-forming agent with minimal Side Effects
(SE)
/.Psyllium (Metamucil) use - Answer-bulk-forming agent with minimal Side Effects (SE)
/.Acetazolamide (Diamox) [diuretic] indication - Answer-edema, epilepsy, acute
mountain sickness, glaucoma (↓ intraocular pressure by ↓ amount of aqueous humor in
the eye) Contra: allergy to sulfonamides
/.Metoprolol (Lopressor) [β-blocker] use and side effects - Answer-Hold dose for
dyspnea (sign of exacerbation of CHF) Propanolol (Inderal) Use. Dysrhythmia, HTN,
angina; SE: bronchoconstriction/bronchospasm; can block glyconeogenesis
/.Norgestrel (Ovrette) use and contraindication - Answer-contraception; SE: excess
progestin →weight gain from ↑ appetite; deficiency of progestin: late breakthrough
bleeding, amenorrhea; excess estrogen → edema Medroxyprogesterone (Provera);
Contra: smoking/tobacco products; Risks: Thromboembolism & Cardiovascular
complications; Interventions: use additional contraceptive measures w/antibiotic therapy
/.IM injection site - Answer-locate dorsogluteal site
