ADVANCED PATHOPHYSIOLOGY
LATEST GUIDE 2025/2026 GRADED
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, 1. A patient was diagnosed as HIV positive several years ago. Which of the following blood tests is most
clinically useful for determining the stage and severity of her disease? CORRECT ANSWERS CD4+ cell counts
2. When the maternal immune system becomes sensitized against antigens expressed by the fetus, what type of
immune reaction occurs? (transfusions, transplant tissues, pregnancy) CORRECT ANSWERS Alloimmune
3. A 10-year-old male is stung by a bee while playing in the yard. He begins itching and develops pains, swelling,
redness and respiratory difficulties. He is suffering from CORRECT ANSWERS anaphylaxis
4. When a patient presents at the ED for an allergic reaction, the nurse rec- ognized the most severe
consequences of a type I hypersensitivity reaction is CORRECT ANSWERS anaphylaxis
5. A nurse recalls that an example of an immune-complex-mediated disease is CORRECT ANSWERS serum
sickness
6. When a nurse cares for a patient with systemic lupus erythematosus (SLE), the nurse remembers this disease is
an example of CORRECT ANSWERS autoimmunity (disturbance in immunologic tolerance of self-antigens)
7. A 30-year-old female c/o fatigue, arthritis, rash and changes in urine color. Laboratory testing reveals anemia,
lymphopenia and kidney inflammation. Assuming a diagnosis of SLE, which of the following is also likely to be
present? CORRECT ANSWERS Autoantibodies
8. A 40-year-old is diagnosed with SLE. Which of the following findings would be considered a symptom of this
disease? CORRECT ANSWERS Photosensitivity + facial rash con- fined to cheeks (malar rash)
9. A person is given an attenuated antigen as a vaccine.When the person asks what was given in the vaccine, how
should the nurse respond? The antigen is CORRECT ANSWERS alive, but less infectious.
10. An immunologist is discussing endotoxin production. Which information should the immunologist include?
Endotoxins are produced by CORRECT ANSWERS gram-nega- tive bacteria.
11. A 50-year-old female experiences decreased blood pressure, decreased oxygen delivery, cardiovascular shock
and subsequent death. A complication of endotoxic shock is suspected. Which of the following is the most likely
cause? CORRECT ANSWERS Gram-negative bacteria
12. Which information indicates a correct understanding of viral vaccines? Most viral vaccines contain
CORRECT ANSWERS attenuated viruses.
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