NSG 552- psychopharmacology Quiz #1,2AND3 (Wilkes University)
Comprehensive Practice Questions Graded A 2025
1. The study of what the body does to drugs: Pharmacokinetics
2. The study of what the drugs does to the Pharmacodynamics
body:
3. Involves the absorption, distribution, me- First Pass Metabolism (C.Y.P. 450)
tabolism and excretion of meds:
4. Increase serum levels of other drugs that are Enzyme inhibitors will slow down metab-
substrates of that enzyme: olism causing toxic levels
5. Decreases serum levels of other drugs that Enzyme inducers cause fast metabolism
are substrates of that enzyme: and create subtherapeutic drug levels
6. Part of the brain that regulates powerful Amygdala
emotions such as fear, rage, sexual desires:
7. The relay station for sensory information: Thalamus
8. Essential for maintaining homeostasis, con- Hypothalamus
trols basic needs such as sleep- wake cycles:
9. This lobe is involved in executive function- Frontal Lobe/ Prefrontal cortex
ing, high order planning, speech and moti-
vation:
10. Derived from Tryptophan and made in the Serotonin
Ralphe Nuclei:
11. Norepinephrine
, NSG 552- psychopharmacology Quiz #1,2AND3 (Wilkes University)
Comprehensive Practice Questions Graded A 2025
Made in the Locus Ceruleus and involved in
the noradrenergic pathways:
12. 90% of serotonin receptors are found in the: GI tract
13. Produced in the V.T.A. (Reward Pathway) and Dopamine
involved in the four major pathways:
14. Dopamine inhibits prolactin in this pathway: Tuberoinfundibular
15. Increase dopamine in this pathway is associ- Mesolimbic Pathway
ated with positive symptoms:
16. Decrease dopamine in this pathway is asso- Mesocortical Pathway
ciated with negative symptoms:
17. Decrease dopamine in this pathway pro- Nigrostriatal Pathway
duces motor symptoms:
18. Main inhibitory neurotransmitter that in- Gamma- aminobutyric acid (GABA), Ott
duces calmness and relaxation: switch
19. Main excitatory neurotransmitter: Glutamate, On Switch
20. Major organ that breaks down drugs in the Liver
body:
21. Electrolyte imbalance commonly associated Hyponatremia
with psychotropic medication use:
22. The time needed to clear 50% if drugs from Half-life
the plasma:
23. Tolerance
, NSG 552- psychopharmacology Quiz #1,2AND3 (Wilkes University)
Comprehensive Practice Questions Graded A 2025
The process of becoming desensitized and
less responsive to a particular medication
dose overtime necessitating an increase:
24. A ration describing toxic dose to effective Therapeutic Index
dose:
25. A chemical that binds to a receptor to pro- Agonist
duce a biologic response:
26. A chemical that binds to a receptor but does Partial Agonist
not fully activate the receptor:
27. A chemical that binds to a receptor, blocking Antagonist
it to inhibit a biologic response:
28. An agent that binds to the same receptor as Inverse Agonist
an agonist but induces an opposite biologi-
cal response:
29. A usually undesired but foreseeable effect Side Ettects
that occurs regardless of dose and often re-
solves after continued therapy:
30. S/S opposite of what it was meant to treat: Paradoxical Reaction
31. The four main dopamine pathways: Mesolimbic, mesocortical, nigrostriatal,
tuberoinfundibular
32. Symptoms of Schizophrenia are divided into positive and negative symptoms
BLANK and BLANK:
33. True or False: Antipsychotic polypharmacy True
can increase the risk of re-hospitalization, di-
, NSG 552- psychopharmacology Quiz #1
Study online at https://quizlet.com/_gsludv
abetes, E.P.S., sedation, seizures, metabolic
effects, mortality, and sudden cardiac death:
34. Alogia, Anhedonia, Avolition and cognitive Negative symptoms
symptoms:
35. Delusions, hallucinations, hostility, positive symptoms
grandiosity:
36. Another name for 1st generation antipsy- Typical
chotics:
37. Another name for 2nd generation antipsy- Atypical
chotics:
38. First line treatment for Schizophrenia: Atypical
39. This class is associated with fewer neurologi- Atypical
cal side effects and effective for both positive
and negative symptoms:
40. This class is effective for only positive symp- Typical
toms and can in fact worsen negative symp-
toms due to decrease DA in the Mesocortical
pathway:
41. Associated with metabolic side effects: Atypical
42. What are the metabolic side effects associat- Weight gain, Hyperlipidemia, diabetes,
ed with Atypical Antipsychotics: hypertension, cardiac and respiratory
side ettects.
43. Typical
Comprehensive Practice Questions Graded A 2025
1. The study of what the body does to drugs: Pharmacokinetics
2. The study of what the drugs does to the Pharmacodynamics
body:
3. Involves the absorption, distribution, me- First Pass Metabolism (C.Y.P. 450)
tabolism and excretion of meds:
4. Increase serum levels of other drugs that are Enzyme inhibitors will slow down metab-
substrates of that enzyme: olism causing toxic levels
5. Decreases serum levels of other drugs that Enzyme inducers cause fast metabolism
are substrates of that enzyme: and create subtherapeutic drug levels
6. Part of the brain that regulates powerful Amygdala
emotions such as fear, rage, sexual desires:
7. The relay station for sensory information: Thalamus
8. Essential for maintaining homeostasis, con- Hypothalamus
trols basic needs such as sleep- wake cycles:
9. This lobe is involved in executive function- Frontal Lobe/ Prefrontal cortex
ing, high order planning, speech and moti-
vation:
10. Derived from Tryptophan and made in the Serotonin
Ralphe Nuclei:
11. Norepinephrine
, NSG 552- psychopharmacology Quiz #1,2AND3 (Wilkes University)
Comprehensive Practice Questions Graded A 2025
Made in the Locus Ceruleus and involved in
the noradrenergic pathways:
12. 90% of serotonin receptors are found in the: GI tract
13. Produced in the V.T.A. (Reward Pathway) and Dopamine
involved in the four major pathways:
14. Dopamine inhibits prolactin in this pathway: Tuberoinfundibular
15. Increase dopamine in this pathway is associ- Mesolimbic Pathway
ated with positive symptoms:
16. Decrease dopamine in this pathway is asso- Mesocortical Pathway
ciated with negative symptoms:
17. Decrease dopamine in this pathway pro- Nigrostriatal Pathway
duces motor symptoms:
18. Main inhibitory neurotransmitter that in- Gamma- aminobutyric acid (GABA), Ott
duces calmness and relaxation: switch
19. Main excitatory neurotransmitter: Glutamate, On Switch
20. Major organ that breaks down drugs in the Liver
body:
21. Electrolyte imbalance commonly associated Hyponatremia
with psychotropic medication use:
22. The time needed to clear 50% if drugs from Half-life
the plasma:
23. Tolerance
, NSG 552- psychopharmacology Quiz #1,2AND3 (Wilkes University)
Comprehensive Practice Questions Graded A 2025
The process of becoming desensitized and
less responsive to a particular medication
dose overtime necessitating an increase:
24. A ration describing toxic dose to effective Therapeutic Index
dose:
25. A chemical that binds to a receptor to pro- Agonist
duce a biologic response:
26. A chemical that binds to a receptor but does Partial Agonist
not fully activate the receptor:
27. A chemical that binds to a receptor, blocking Antagonist
it to inhibit a biologic response:
28. An agent that binds to the same receptor as Inverse Agonist
an agonist but induces an opposite biologi-
cal response:
29. A usually undesired but foreseeable effect Side Ettects
that occurs regardless of dose and often re-
solves after continued therapy:
30. S/S opposite of what it was meant to treat: Paradoxical Reaction
31. The four main dopamine pathways: Mesolimbic, mesocortical, nigrostriatal,
tuberoinfundibular
32. Symptoms of Schizophrenia are divided into positive and negative symptoms
BLANK and BLANK:
33. True or False: Antipsychotic polypharmacy True
can increase the risk of re-hospitalization, di-
, NSG 552- psychopharmacology Quiz #1
Study online at https://quizlet.com/_gsludv
abetes, E.P.S., sedation, seizures, metabolic
effects, mortality, and sudden cardiac death:
34. Alogia, Anhedonia, Avolition and cognitive Negative symptoms
symptoms:
35. Delusions, hallucinations, hostility, positive symptoms
grandiosity:
36. Another name for 1st generation antipsy- Typical
chotics:
37. Another name for 2nd generation antipsy- Atypical
chotics:
38. First line treatment for Schizophrenia: Atypical
39. This class is associated with fewer neurologi- Atypical
cal side effects and effective for both positive
and negative symptoms:
40. This class is effective for only positive symp- Typical
toms and can in fact worsen negative symp-
toms due to decrease DA in the Mesocortical
pathway:
41. Associated with metabolic side effects: Atypical
42. What are the metabolic side effects associat- Weight gain, Hyperlipidemia, diabetes,
ed with Atypical Antipsychotics: hypertension, cardiac and respiratory
side ettects.
43. Typical
