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HESI Mental Health NGN Study Guide – 2025/2026 Edition | Comprehensive Review for Next Generation NCLEX Mental Health Questions

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This 2025/2026 edition of the Mental Health NGN Study Guide provides a detailed and structured review tailored to the mental health section of the Next Generation NCLEX (NGN). It covers critical topics such as therapeutic communication, psychiatric disorders, crisis intervention, legal/ethical considerations, and psychopharmacology. The guide includes NGN-style case studies, clinical judgment questions, and evidence-based rationales to help nursing students build confidence and critical thinking skills for mental health scenarios.

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Mental Health NGN Study Guide - 2025 Edition
Comprehensive Review for Next Generation NCLEX Mental Health Questions

Table of Contents
1. Introduction to Mental Health NGN

2. Anxiety and Mood Disorders

3. Psychotic Disorders

4. Substance Use Disorders

5. Personality Disorders
6. Therapeutic Communication

7. Psychopharmacology

8. Crisis Intervention
9. Legal and Ethical Issues

10. NGN Question Formats Guide



Introduction to Mental Health NGN
The Next Generation NCLEX (NGN) emphasizes clinical judgment and decision-making in mental
health nursing. This study guide provides practice questions in various NGN formats to help you
develop critical thinking skills essential for safe psychiatric nursing practice.

Key Mental Health Nursing Concepts:
Therapeutic relationship building

Safety assessment and management

Medication administration and monitoring

Crisis de-escalation techniques

Patient advocacy and rights
Evidence-based interventions



Anxiety and Mood Disorders
Case Study 1: Major Depressive Disorder

, Clinical Scenario: Sarah, a 28-year-old teacher, is admitted to the psychiatric unit with major
depressive disorder. She reports feeling hopeless, has lost 15 pounds in the past month, sleeps only 2-
3 hours per night, and states "I can't concentrate on anything anymore. My students deserve better."

NGN Question 1 (Multiple Response - Select All That Apply)
Which assessment findings are consistent with major depressive disorder? Select all that apply.

A) ☐ Significant weight loss
B) ☐ Insomnia
C) ☐ Difficulty concentrating
D) ☐ Feelings of worthlessness
E) ☐ Increased energy levels
F) ☐ Psychomotor agitation or retardation
G) ☐ Euphoric mood

Correct Answers: A, B, C, D, F

Rationale:

A) Weight loss is a common symptom of depression due to appetite changes

B) Sleep disturbances, including insomnia, are core symptoms
C) Concentration difficulties are cognitive symptoms of depression
D) Feelings of worthlessness and guilt are characteristic

E) INCORRECT - Depression typically involves decreased energy (fatigue)

F) Psychomotor changes (agitation or retardation) are diagnostic criteria
G) INCORRECT - Euphoric mood would suggest mania, not depression

NGN Question 2 (Drag and Drop - Prioritization)
Drag the nursing interventions in order of priority for Sarah's care (1 = highest priority, 5 = lowest
priority):

Available Options:

Assess suicide risk and implement safety measures
Encourage participation in group therapy

Monitor food and fluid intake
Administer prescribed antidepressant medication

Establish therapeutic rapport

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