Part I: Basic Immunologic Mechanisms
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1. Highlights of Innate and Adaptive Immune Systems
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2. Soluble Mediators of the Immune System
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3. Antigens and Antibodies
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4. Cellular Activities and Clinical Disorders of Innate and Adaptive Immunity
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Part II: The Theory of Immunologic and Serologic Procedures
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5. Basic Safety in the Immunology-Serology Laboratory
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6. Quality Assurance and Quality Control Practices
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7. Basic Serologic Laboratory: Techniques and Clinical Applications
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8. Precipitation and Particle Agglutination Methods
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9. Electrophoresis Techniques
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10. Labeling Techniques in Immunoassay
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11. Flow Cytometry
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12. Molecular Laboratory Techniques
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Part III: Immunologic Manifestations of Infectious Diseases
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13. Infectious Diseases: Overview & TORCH Diseases
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14. Streptococcal Infections
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15. Syphilis
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16. Vector-Borne Diseases
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17. Infectious Mononucleosis
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18. Viral Hepatitis
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Part IV: Immune Disorders
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19. Primary and Acquired (Secondary) Immune Deficiencies
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20. Hypersensitivity Reactions
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21. Immunoproliferative Disorders
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22. Tolerance, Autoimmunity and Autoimmune Disorders
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23. Systemic Lupus Erythematosus
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,24. Rheumatoid Arthritis
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Part V: Transplantation & Tumor Immunology
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25. Transplantation: HLA, Solid Organ, and Hematopoietic Stem Cells
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26. Tumor Immunology and Up-to-Date Applications of Next Generation Sequencing
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Part VI: Vaccines
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27. Primer on Vaccines
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hapter 01: Highlights of the Innate and Adaptive Immune Systems
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MULTIPLE CHOICE a
1. The ―father‖ of immunology is generally considered to be
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a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS: B a
Louis Pasteur is generally considered to be the ―father of immunology.‖
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DIF: Cognitive Level: I a a
2. An early form of immunization was practiced by the
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a. Romans.
b. Greeks.
c. Chinese.
d. Native Americans. a
ANS: C a
Beginning about 1000 AD, the Chinese practiced a form of immunization by inhaling dried powde
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rs derived from the crusts of smallpox lesions.
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DIF: Cognitive Level: I a a
3. A specific function of the immune system is to
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a. recognize self from nonself. a a a
b. defend the body against nonself. a a a a
c. amplify specific functions. a a
d. Both A and B. a a a
ANS: D a
The function of the immune system is to recognize self from nonself and defend the body against n
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onself. Such a system is necessary for survival. The immune system also has nonspecific effector
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mechanisms that usually amplify the specific functions. Nonspecific components of the immune s
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ystem include mononuclear phagocytes, polymorphonuclear leukocytes, and soluble factors (e.g.
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, complement).
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DIF: Cognitive Level: I a a
, 4. An undesirable consequence of immunity is
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a. natural resistance.
a
b. acquired resistance to infectious diseases.
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