1
C785 Biochemistry preassessment Questions
with Correct Answers for a Specific Exam Mail
Assuming 100% reaction efficiency, how many DNA copies are created after
the completion of four complete PCR cycles?
Ans: 16
What is the function of DNA polymerase in the process of PCR?
Ans: It recognizes the primers and uses the available dNTPs to replicate the
template DNA sequence.
What are possible blood types of the parents of a patient with blood type
AB?
Ans: A and B
115 116 117 118 − Amino Acid Number
Tyr Gly Thr Pro − Amino Acid Sequence
TAC GGG ACA CCA − DNA Sequence
What is the amino acid in position 118 that results from a single nucleotide
insertion immediately following the three guanines that encode for glycine
116?
Ans: Thr
Pretest - Stuvia US
, 2
In sickle-cell disease, the glutamic acid (Glu) at position number seven is
mutated to valine (Val).
What change in codons corresponds to this mutation?
Ans: GAA to GTA
Which type of mammalian DNA damage repair requires the presence of the
chromosome that is homologous to the damaged chromosome?
Ans: Recombination
Xeroderma pigmentosum (XP) is a recessive genetic disease that occurs
when one or more of the genes that perform nucleotide excision repair are
nonfunctional.
Why do XP patients have a much higher incidence of skin cancer than the
general population?
Ans: The mutation rate of all other genes is higher due to failure to repair.
Which mRNA sequence results in a polypeptide that contains three amino
acids?
Ans: 5' - CUU GAU ACU UAG - 3'
Which template strand DNA sequence would result in the amino acid (Ser)?
Ans: 5' - CGA - 3'
What is the complementary sequence for the following DNA sequence?
Pretest - Stuvia US
C785 Biochemistry preassessment Questions
with Correct Answers for a Specific Exam Mail
Assuming 100% reaction efficiency, how many DNA copies are created after
the completion of four complete PCR cycles?
Ans: 16
What is the function of DNA polymerase in the process of PCR?
Ans: It recognizes the primers and uses the available dNTPs to replicate the
template DNA sequence.
What are possible blood types of the parents of a patient with blood type
AB?
Ans: A and B
115 116 117 118 − Amino Acid Number
Tyr Gly Thr Pro − Amino Acid Sequence
TAC GGG ACA CCA − DNA Sequence
What is the amino acid in position 118 that results from a single nucleotide
insertion immediately following the three guanines that encode for glycine
116?
Ans: Thr
Pretest - Stuvia US
, 2
In sickle-cell disease, the glutamic acid (Glu) at position number seven is
mutated to valine (Val).
What change in codons corresponds to this mutation?
Ans: GAA to GTA
Which type of mammalian DNA damage repair requires the presence of the
chromosome that is homologous to the damaged chromosome?
Ans: Recombination
Xeroderma pigmentosum (XP) is a recessive genetic disease that occurs
when one or more of the genes that perform nucleotide excision repair are
nonfunctional.
Why do XP patients have a much higher incidence of skin cancer than the
general population?
Ans: The mutation rate of all other genes is higher due to failure to repair.
Which mRNA sequence results in a polypeptide that contains three amino
acids?
Ans: 5' - CUU GAU ACU UAG - 3'
Which template strand DNA sequence would result in the amino acid (Ser)?
Ans: 5' - CGA - 3'
What is the complementary sequence for the following DNA sequence?
Pretest - Stuvia US
