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ONS/ONCC CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATION LATEST EXAM 2024 QUESTIONS AND CORRECT DETAILED ANSWERS |GRADED A+

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ONS/ONCC CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATION LATEST EXAM 2024 QUESTIONS AND CORRECT DETAILED ANSWERS |GRADED A+

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ONS/ONCC CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATION
LATEST EXAM 2025 QUESTIONS AND CORRECT DETAILED ANSWERS
|GRADED A+|| PROFESSOR VERIFIED




Lesson 1: Foundations to Set the Stage -CORRECT ANSWER



Focusing on Cellular Structure and Function -CORRECT ANSWER



The Normal Cell Cycle -CORRECT ANSWER-The cell cycle refers to the ordered seres of
processes of DNA replication and mitosis, or cell division



-Cell nucleus regulates these processes by gathering and processing complexes molecular
information



Interphase and Mitotic Phase -CORRECT ANSWERCell division produces two identical cells
through these two major phases



During interphase: -CORRECT ANSWERCell grows and DNA is replicated through the
following three steps:



1: First growth phase (G1 or first gap)



2: Synthesis phase (S phase)



3:Mitotic Phse (M phase)

,First Growth Phase (G1 or first gap) -CORRECT ANSWER-cells increase in size



-reproduce RNA



-"quality assurance" test that the cell will be ready to synthesis DNA



-Length of time is variable, can be from hours to days



Synthesis Phase (S phase) -CORRECT ANSWER-DNA replicates



-Results in the formation of identical pairs of DNA (chromatids)



-which are attached a t the centromere



-lasts 2-10 hours



Mitotic Phase (M phase) -CORRECT ANSWER-Replicated chromosomes are aligned,
separated, and move into 2 new, identical daughter cells



-takes about 30-60 minutes



Major points of cell regulation are entry and exit from -CORRECT ANSWER-G1 checkpoint



-S Phase

,-G2 checkpoint



-M phase



Restriction Point -CORRECT ANSWER-The transition from the resting phase into an actively
dividing phase (G0-G1) is a point where cellular transformation can occur



-During this time, cells pass through a transition phase known as a restriction point



-Extracellular growth factors trigger reentry into G1, and GF are required to send the cells past
the restriction point, or the point of no return



G0 Phase (resting phase) -CORRECT ANSWER-After mitosis, cells may enter back into the
G1 phase or go into a resting phase, known as G0



-Most cells in the human body reside in G0



-Exceptions to this are those that are (Resting in G0 phase) -CORRECT ANSWER-Exceptions
to this are those that are metabollically active, such as



-granulocytes



-and the epithelium of the GI tract



Cell Cycling Time -CORRECT ANSWERAmount of time from mitosis to mitosis

, Cell cycle video and image -CORRECT
ANSWERhttp://highered.mheducation.com/sites/0072495855/student_view0/chapter2/anim
ation__how_the_cell_cycle_works.html



Check points in the Cell Cycle: Keeping it All Under Control -CORRECT ANSWER-The cell
cycle is carefully controlled through a series of checkpoints



-Variation in duplication or distribution of chromosomes during cell division can alter the
genetic information passed on to daughter cells, leading to cellular dysfunction and disease,
such as cancer



-These checkpoints monitor for DNA integrity and control progression through mitosis



Progression through the cell cycle is controlled through two proteins: -CORRECT ANSWER1.
cyclines (D, E, A, B)



2. Cyclin-dependent kinases (CDKs)



-Cyclin-CDK complex allows the cell to progress through each phase of the cell cycle



Locations of proteins Cyclins (D, E, A, B) and CDKs -CORRECT ANSWER-(G0-G1) : Cyclin D
and CDK 4/6



-Early S: Cyclin E and CDK 1/2



-Late S: Cyclin A and CDK 1/2



-G2: CDK 1/2 and cyclin A

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