Mood d/o ~CORRECT ANSWER~Serotonin, NE, Glutamate, and
Dopamine are implicated in mood regulation
Serotonin ~CORRECT ANSWER~low levels cause depression
Norepinephrine (NE) ~CORRECT ANSWER~imbalances contribute to
anxiety
Dopamine ~CORRECT ANSWER~plays a role in motivation and reward
elevated levels cause mania or hypomania
GABA (Gamm-Aminobutyric Acid) ~CORRECT ANSWER~the most
abundant inhibitory neurotransmitter in the brain
Glutamate ~CORRECT ANSWER~is an excitatory NT that can influence
mood and behavior
dysregulation can cause impulsivity and aggression
Acetylcholine ~CORRECT ANSWER~associated w/ cognitive function
, Endorphins ~CORRECT ANSWER~are involved in pain modulation
Histamine ~CORRECT ANSWER~plays a role in alertness and sleep-
wake cycle
Lithium ~CORRECT ANSWER~Normal 0.6-1.2 mEq/L
modulates glutamate receptors, reducing impulsivity
ETOH, NSAIDS, Hyponatremia may increase Lithium levels
Hypokalemia may decrease Lithium levels
Can cause congenital malformation, esp. in 1st trimester
Valproic acid (Depakote) ~CORRECT ANSWER~Mood stabilizer
May cause Hepatotoxicity, Pancreatitis, and Hyperammonemia (hand
tremor, polydipsia, polyuria)
Can cause neural tube defects and other congenital malformations in
pregnancy