CCTN General Exam Questions with
Correct Solutions
#1 reason for kidney dysfunction post [any] transplant? - ANSWER immunosuppressants (CNI),
a nephrotoxic med
#1 reason for hyperlipidemia post [any] transplant? - ANSWER pre existing hyperlipidemia
other reasons:
-cyclosporins (increases cholesterol AND TG). prograf not as
much -rapamycin
statins lower cholesterol but at risk of rhabdomyolysis. Check CK value for that
Post transplant med that contribute to osteoporosis? - ANSWER -steroids
-cyclosprin
-prograf
-azathioprine
-cellcept
-sirolimus
What do you take biphosphonates for? - ANSWER -to prevent loss of bone density. take if
dx with osteoporosis. take in conjunction with calcium and Vit D.
-taken in morning with full glass of water
-30 min before food
,-sit upright for 30 min after
-don't drink for 30 min after
What post tx meds contribute to post tx diabetes? - ANSWER -steroids
-cyclosporin
-prograf
goal BG < 126
What meds do you treat PTLD with? - ANSWER a. acyclovir AND
b. gangcyclovir
c. radiation therapy OR
d. surgical excision of lymph node
e. decrease immunosuppressive therapy
What does MELD consist of? - ANSWER -dialysis twice in the past week?
-creatinine
-bilirubin
-INR
-sodium
Causes of impotence in men pre transplant? What post transplant meds add to impotence
post transplant? - ANSWER -diabetes
-CAD
-HTN
, -Beta Blockers for CHF management
-immunosuppressants can cause impotence
What are common infections in the 1st month post transplant? - ANSWER -post
op complications, ie, UTI from foley
-allograft infection from donor
-HSV reactivation
-HH6
-toxoplasma gondii (in heart tx)
-candida (in lung tx)
What are common infection in months 2-6 post transplant? - ANSWER -opportunistic organisms
-CMV
-EBV
-PJP pna
-listeria monocytogenes
-karposi's sarcoma
What are common infection in months 6+ post transplant? - ANSWER -from public exposure
-upper respiratory tract infection, i.e., flu
-UTI
-pneumococca pna
-varicella
What does HHV6 cause in a post tx patient? - ANSWER *affects stem cell transplant patients*
-bone marrow suppression
Correct Solutions
#1 reason for kidney dysfunction post [any] transplant? - ANSWER immunosuppressants (CNI),
a nephrotoxic med
#1 reason for hyperlipidemia post [any] transplant? - ANSWER pre existing hyperlipidemia
other reasons:
-cyclosporins (increases cholesterol AND TG). prograf not as
much -rapamycin
statins lower cholesterol but at risk of rhabdomyolysis. Check CK value for that
Post transplant med that contribute to osteoporosis? - ANSWER -steroids
-cyclosprin
-prograf
-azathioprine
-cellcept
-sirolimus
What do you take biphosphonates for? - ANSWER -to prevent loss of bone density. take if
dx with osteoporosis. take in conjunction with calcium and Vit D.
-taken in morning with full glass of water
-30 min before food
,-sit upright for 30 min after
-don't drink for 30 min after
What post tx meds contribute to post tx diabetes? - ANSWER -steroids
-cyclosporin
-prograf
goal BG < 126
What meds do you treat PTLD with? - ANSWER a. acyclovir AND
b. gangcyclovir
c. radiation therapy OR
d. surgical excision of lymph node
e. decrease immunosuppressive therapy
What does MELD consist of? - ANSWER -dialysis twice in the past week?
-creatinine
-bilirubin
-INR
-sodium
Causes of impotence in men pre transplant? What post transplant meds add to impotence
post transplant? - ANSWER -diabetes
-CAD
-HTN
, -Beta Blockers for CHF management
-immunosuppressants can cause impotence
What are common infections in the 1st month post transplant? - ANSWER -post
op complications, ie, UTI from foley
-allograft infection from donor
-HSV reactivation
-HH6
-toxoplasma gondii (in heart tx)
-candida (in lung tx)
What are common infection in months 2-6 post transplant? - ANSWER -opportunistic organisms
-CMV
-EBV
-PJP pna
-listeria monocytogenes
-karposi's sarcoma
What are common infection in months 6+ post transplant? - ANSWER -from public exposure
-upper respiratory tract infection, i.e., flu
-UTI
-pneumococca pna
-varicella
What does HHV6 cause in a post tx patient? - ANSWER *affects stem cell transplant patients*
-bone marrow suppression
