Nanomed Final QUESTIONS AND ASNWERS YEAR
2025.
What is nanomedicine? - the application of nanotechnology in addressing current issues
and problems that are faced in medicine and healthcare - ✅✅What is the primary
rationale of working at the nanoscale range? - it enables scientists to utilize the unique
physical, chemical, and biological properties possessed by the materials at such small
dimensions - ✅✅What are the key properties of the nanoscale range? - 1. high
surface area to volume ratio
2. quantum effects dominate at this scale
3. biological scale - ✅✅What is the rationale of using nanotechnology in medicine? -
at the nanoscale certain materials exhibit different and chemical properties that are
potentially beneficial - ✅✅When the bulk material is broken down into smaller
materials such that the volume of the particles remains the same as the bulk material,
the sum of the surface area of the smaller particles is less than the surface area of the
bulk material. True or False? - false - ✅✅Molecular self-assembly is a top down
approach for synthesis of nano-materials. True or False? - false - ✅✅What are the
three components of a nucleotide? - sugar, phosphate, nitrogen base - ✅✅DNA is the
only molecule that is capable of replicating itself? True or False? - true - ✅✅Can
proteins duplicate themselves? - no - ✅✅In replication, DNA polymerase adds bases
from 5' to 3' direction from scratch. True or False? - false - ✅✅State True of False:In
the figure two gene promoter constructs are shown A and B. Using genetic engineering
one flips the position of the genes and promoters in the construct resulting in the
construct shown in C. In the case C, on turning on the promoter 1 there will be
expression of gene 2.
A) promoter 1, gene 1
B) promoter 2, gene 2
C) promoter 1, gene 2 - true - ✅✅In the cell where does the processes of replication,
transcription and translation take place? - Replication-Nucleus, Transcription-Nucleus,
Translation-Cytoplasm - ✅✅It is desired to produce Keratinocyte Growth Factor
(KGF) recombinantly. To this end, a construct containing the gene encoding KGF in
front of the eukaryotic promoter CMV was created. Which host will you select for
producing large quantities of KGF using this construct? - eukaryotic host - ✅✅State
True or False. " A researcher is trying to identify the role of protein A in a particular
disease. He decides to look at expression of the gene encoding protein A in diseased
and healthy individuals. He finds that there are no differences in gene expression of A
and hence concludes that protein A plays no role in the pathogenesis of the described
disease" - false - ✅✅recombinant protein production - produce proteins that are
lacking or non-functional in a particular disease then administer it to the cell (ex. insulin
and growth factors) - ✅✅gene therapy - somehow change the existing cells in the
2025.
What is nanomedicine? - the application of nanotechnology in addressing current issues
and problems that are faced in medicine and healthcare - ✅✅What is the primary
rationale of working at the nanoscale range? - it enables scientists to utilize the unique
physical, chemical, and biological properties possessed by the materials at such small
dimensions - ✅✅What are the key properties of the nanoscale range? - 1. high
surface area to volume ratio
2. quantum effects dominate at this scale
3. biological scale - ✅✅What is the rationale of using nanotechnology in medicine? -
at the nanoscale certain materials exhibit different and chemical properties that are
potentially beneficial - ✅✅When the bulk material is broken down into smaller
materials such that the volume of the particles remains the same as the bulk material,
the sum of the surface area of the smaller particles is less than the surface area of the
bulk material. True or False? - false - ✅✅Molecular self-assembly is a top down
approach for synthesis of nano-materials. True or False? - false - ✅✅What are the
three components of a nucleotide? - sugar, phosphate, nitrogen base - ✅✅DNA is the
only molecule that is capable of replicating itself? True or False? - true - ✅✅Can
proteins duplicate themselves? - no - ✅✅In replication, DNA polymerase adds bases
from 5' to 3' direction from scratch. True or False? - false - ✅✅State True of False:In
the figure two gene promoter constructs are shown A and B. Using genetic engineering
one flips the position of the genes and promoters in the construct resulting in the
construct shown in C. In the case C, on turning on the promoter 1 there will be
expression of gene 2.
A) promoter 1, gene 1
B) promoter 2, gene 2
C) promoter 1, gene 2 - true - ✅✅In the cell where does the processes of replication,
transcription and translation take place? - Replication-Nucleus, Transcription-Nucleus,
Translation-Cytoplasm - ✅✅It is desired to produce Keratinocyte Growth Factor
(KGF) recombinantly. To this end, a construct containing the gene encoding KGF in
front of the eukaryotic promoter CMV was created. Which host will you select for
producing large quantities of KGF using this construct? - eukaryotic host - ✅✅State
True or False. " A researcher is trying to identify the role of protein A in a particular
disease. He decides to look at expression of the gene encoding protein A in diseased
and healthy individuals. He finds that there are no differences in gene expression of A
and hence concludes that protein A plays no role in the pathogenesis of the described
disease" - false - ✅✅recombinant protein production - produce proteins that are
lacking or non-functional in a particular disease then administer it to the cell (ex. insulin
and growth factors) - ✅✅gene therapy - somehow change the existing cells in the
