ONS CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATE
EXAMNEWST ACTUAL 2025/2026 QUESTIONS AND ANSWERS
VERIFIED /GRADED A+
Common constipation-causing agents: - -----Answers---
Vinca alkaloids (vincristine and vinorelbine)
Thalidomide
Lenalidomide
Bortezomib
6 main types of immunotherapy - -----Answers---1.
Monoclonal antibodies
2. Immune checkpoint inhibitors
3. Cancer vaccines
4. Nonspecific immunotherapies
5. Adoptive cell therapy (CAR T-cell therapy)
6. Oncolytic virus therapy
mAbs MOA - -----Answers---Mark cancer cell surface
receptor/antigen to make the cell visible to the immune
system to destroy
Different types of mAbs used in treatment of cancer - -----
Answers---Naked mAbs
Conjugated monoclonal antibodies
Bispecific monoclonal antibodies
,mAbs ending in "-ximab" source - -----Answers---Chimeric
human-mouse
mAbs ending in "-zumab" source - -----Answers---
Humanized mouse
mAbs ending in "-umab" source - -----Answers---Fully
human
mAbs ending in "-omab" source - -----Answers---Murine
mouse
Immune checkpoint inhibitors MOA - -----Answers---Prevent
cancer cells from turning off T cells --> allows T cells to
infiltrate a tumor and stop it from growing
Immune checkpoint inhibitors initially cause tumors to swell,
making it appear as if the tumor is growing. This is called
_____________ - -----Answers---Pseudoprogression
2 main types of cancer vaccines - -----Answers---
Preventative/prophylactic
Treatment/therapeutic
Nonspecific immunotherapies MOA - -----Answers---
Stimulating the immune system in a general way, hopefully
leading to a better immune response against cancer cells
, Adoptive cell therapy MOA - -----Answers---T cells collected
from patient
T cells grown in laboratory
*This increases amount of T cells able to kill cancer cells or
fight infections*
T cells given back to patient to help immune system
Oncolytic virus therapy MOA - -----Answers---Naturally
occurring or genetically engineered virus that can infect and
kill a cancer call without harming normal cells
Common side effects of immunotherapies - -----Answers---
Fatigue
Diarrhea
Colitis
Musculoskeletal pain
Dermatitis
Common treatment for immunotherapy side effects - -----
Answers---Corticosteroids
Results of immunotherapy agents most commonly occur
between ____________ after starting therapy - -----Answers---
12-16 weeks
EXAMNEWST ACTUAL 2025/2026 QUESTIONS AND ANSWERS
VERIFIED /GRADED A+
Common constipation-causing agents: - -----Answers---
Vinca alkaloids (vincristine and vinorelbine)
Thalidomide
Lenalidomide
Bortezomib
6 main types of immunotherapy - -----Answers---1.
Monoclonal antibodies
2. Immune checkpoint inhibitors
3. Cancer vaccines
4. Nonspecific immunotherapies
5. Adoptive cell therapy (CAR T-cell therapy)
6. Oncolytic virus therapy
mAbs MOA - -----Answers---Mark cancer cell surface
receptor/antigen to make the cell visible to the immune
system to destroy
Different types of mAbs used in treatment of cancer - -----
Answers---Naked mAbs
Conjugated monoclonal antibodies
Bispecific monoclonal antibodies
,mAbs ending in "-ximab" source - -----Answers---Chimeric
human-mouse
mAbs ending in "-zumab" source - -----Answers---
Humanized mouse
mAbs ending in "-umab" source - -----Answers---Fully
human
mAbs ending in "-omab" source - -----Answers---Murine
mouse
Immune checkpoint inhibitors MOA - -----Answers---Prevent
cancer cells from turning off T cells --> allows T cells to
infiltrate a tumor and stop it from growing
Immune checkpoint inhibitors initially cause tumors to swell,
making it appear as if the tumor is growing. This is called
_____________ - -----Answers---Pseudoprogression
2 main types of cancer vaccines - -----Answers---
Preventative/prophylactic
Treatment/therapeutic
Nonspecific immunotherapies MOA - -----Answers---
Stimulating the immune system in a general way, hopefully
leading to a better immune response against cancer cells
, Adoptive cell therapy MOA - -----Answers---T cells collected
from patient
T cells grown in laboratory
*This increases amount of T cells able to kill cancer cells or
fight infections*
T cells given back to patient to help immune system
Oncolytic virus therapy MOA - -----Answers---Naturally
occurring or genetically engineered virus that can infect and
kill a cancer call without harming normal cells
Common side effects of immunotherapies - -----Answers---
Fatigue
Diarrhea
Colitis
Musculoskeletal pain
Dermatitis
Common treatment for immunotherapy side effects - -----
Answers---Corticosteroids
Results of immunotherapy agents most commonly occur
between ____________ after starting therapy - -----Answers---
12-16 weeks
