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NR 341 Pharmacology CJE Benchmark Exam 2026 – Chamberlain University – Complete Practice Exam with Rationales complex care

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This document contains a comprehensive NR 341 Pharmacology CJE Benchmark practice exam for Chamberlain University with rationales and nursing-focused pharmacology questions. Topics include medication administration, cardiovascular drugs, diabetes management, pain control, endocrine therapies, antibiotics, anticoagulants, respiratory medications, and medication safety principles. The material includes multiple-choice, select-all-that-apply, dosage calculation, and clinical application questions designed to strengthen pharmacology knowledge, nursing judgment, and exam preparation skills.NR341 Exam 1 Concept Review -- 60 questions Complex care (Chamberlain University) Pain Medications and reversal agents ● For opioid analgesics the antidote for overdose is nalaxone (Narcan) ● Morphine ○ Reversal agent: Narcan (naloxone) ■ Narcan half-life is shorter than morphine ■ Wears off before morphine ■ Must reassess patient RR ○ Side effects ■ Drowsiness, dizziness, constipation ○ Adverse effect ■ Hypotension, bradycardia, and respiratory depression ○ Nursing interventions ■ reassess : IV 5-15 min, PO 30-45 min, IM 15-30 min ○ Education ■ 1 .Change position slowly ■ 2 .Use the call light, do not try to get out of bed without help. ■ 3 .What for nausea and vomiting--antiemetics (ondansetron ● Benzodiazepines ○ Sedative -- NO ANALGESIC EFFECTS ○ Used for ventilator/anesthesia adjunct ○ AE: Monitor for respiratory depression ○ Reversal: flumazenil (Romazicon)

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NR341 Exam 1 Concept Review -- 60 questions
Complex care (Chamberlain University)



Chapters for this exam 11th edition
Chapter 65: Critical Care, pages 1533-1536 (Overview of Critical Care)
Chapter 9: Palliative Care at the end of Life
Chapter 18: Intraoperative Care, pages 322-324 Table 18-6 and 18-7 (Opioids, Benzodiazepines,
Neuromuscular Blocking Agents, Dexmedetomidine, Propofol)

Chapter 16: Fluid, Electrolyte, and Acid-Base Imbalances pages 286-291.
Chapter 26: Upper Respiratory Problems,pages 485-490
Chapter 65: Critical Care, pages 1547-1563 Beginning with Non-invasive
ventilation.
Chapter 67: Acute Respiratory Failure and Acute Respiratory Distress Syndrome, pages 1588-1603

Chapter 33: Coronary Artery Disease and Acute Coronary Syndrome
Chapter 34: Heart Failure
Chapter 35: Dysrhythmias


⭐MEDS
Pain Medications and reversal agents
● For opioid analgesics the antidote for overdose is nalaxone (Narcan)
● Morphine
○ Reversal agent: Narcan (naloxone)
■ Narcan half-life is shorter than morphine
■ Wears off before morphine
■ Must reassess patient RR
○ Side effects
■ Drowsiness, dizziness, constipation
○ Adverse effect
■ Hypotension, bradycardia, and respiratory depression
○ Nursing interventions
■ reassess : IV 5-15 min, PO 30-45 min, IM 15-30 min
○ Education
■ 1 .Change position slowly
■ 2 .Use the call light, do not try to get out of bed without help.
■ 3 .What for nausea and vomiting--antiemetics (ondansetron )




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■ 4 .May cause itching, call immediately if rash develops or throat starts swelling.
■ 5 . May cause constipation (increase fluids and fiber, stool softener )




● Benzodiazepines
○ Sedative -- NO ANALGESIC EFFECTS
○ Used for ventilator/anesthesia adjunct
○ AE: Monitor for respiratory depression
○ Reversal: flumazenil (Romazicon)
● Propofol (Diprivan) - non barbiturate hypnotic ○ Reversal agent: NONE
○ Sedative -- NO ANALGESIC EFFECTS
○ Used for ventilator/anesthesia adjunct
○ Very short half life
○ AE:
■ Resp depression (pt must be on ventilator or have someone in the room who can
intubate)
■ Severe hypotension
■ CNS depression
■ Hyperlipidemia
■ Infection risk (tubing changed q12h)
○ Interventions
■ MAINTAIN PATENT AIRWAY
● Dexmedetomidine (Precedex) -sedative
○ Antidote: Atipamezole
○ Adverse Effects: Hypotension, Nausea, Bradycardia
○ Should be used for no longer than 24 hours. Monitor HR, Liver, and Renal function.
○ No respiratory depression and anti-anxiety, can be used prior to surgery.
○ Analgesic and hypnotic, patient semi-arousable.
○ Rebound hypertension.








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Drugs to know: (therapeutic effects, adverse effects) -- WHEN THE QUESTION ASKS WHAT THE
MED IS FOR REMEMBER TO READ THE SCENARIO CAREFULLY -- SOME MEDS ARE
GENERALLY KNOWN TO DO 1 THING BUT CAN DO SOMETHING ELSE PERTAINING TO
THE SITUATION
● Dopamine
○ Inotropic, vasopressor
○ Therapeutic effect: increase BP, HR, cardiac output
○ ADVERSE EFFECTS
■ CNS: Headache, anxiety
■ CV: Palpitations, tachycardia, hypertension, ectopic beats, angina, wide QRS
complex, peripheral vasoconstriction, hypotension
■ GI: Nausea, vomiting, diarrhea
■ INTEG: Necrosis, tissue sloughing with extravasation, gangrene
■ RESP:Dyspnea
● Nitroglycerin
○ Nitrate
○ Treat or prevent angina (chest pain) -- caused by vasoconstriction of coronary arteries
○ Causes vasodilation in coronary arteries
■ SE: headache, orthostatic hypotension
○ 3 nitro 5 min in between SUBLINGUAL (Nitrostat)
■ Call 911 during 2nd nitro
○ Do not give with viagara (this drug causes vasodilation as well) -- if taken together will
be fatal
○ ADVERSE EFFECTS
■ CNS: Headache, flushing, dizziness
■ CV: Postural hypotension, tachycardia, collapse, syncope, palpitations




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■ GI: Nausea, vomiting
■ INTEG: Pallor, sweating, rash
● Atropine--antidysrhythmic
○ Blocks acetylcholine → increase cardiac output & HR by blocking vagal stimulation to
the heart
■ Increase HR in sinus bradycardia < 40-50*
○ Anticholinergic -- Dry up secretions
○ ADVERSE EFFECTS
■ CNS: Headache, dizziness, involuntary movement, confusion, psychosis,
anxiety, coma, flushing, drowsiness, insomnia, weakness, delirium (geriatric)
■ CV: Hypo/hypertension, paradoxical bradycardia, angina, PVCs, tachycardia,
ectopic ventricular beats, bradycardia, palpitations
■ EENT: Blurred vision, photophobia, glaucoma, eye pain, pupil dilatation, nasal
congestion, increased intraoccular pressure
■ GI: Dry mouth, nausea, vomiting, abdominal pain, anorexia, constipation,
paralytic ileus, abdominal distention, altered taste GU: Retention,
hesitancy, impotence, dysuria








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