2024/25|MATERIAL
PHARMACOLOGY PRINCIPLES
NUR 210 EXAM 1|2025-2026
LATEST VERSION|
COMPREHENSIVE QUESTIONS
AND VERIFIED
ANSWERS/ACCURATE
SOLUTIONS|ALREADY
GRADED A+
drug response correct answers >> the intensity
of the drug response is directly related to the
concentration of the drug at the SITE OF ACTION
Goal is to:
- maximize the beneficial effects- concentration
high enough for desired response
- minimize harm- avoid to high a concentration
GRADED A+
,Three phases of drug action correct answers >>
1. pharmaceutic phase (dissolution)
2. pharmacokinetic phase (drug moving through
the body)
3. pharmacodynamic phase (what the drug does to
the body)
1. pharmaceutic phase correct answers >> the
drug goes into solution
- Dissolution: the process by which a drug goes into
solution and becomes available for absorption
- must be dissolved before it can be absorbed
- most absorption takes place in the small intestine
2. pharmacokinetic phase: four processes correct
answers >> "what the BODY does to the drug"
- absorption
- distribution
- metabolism/ biotransformation
- exertion
GRADED A+
,pharmacokinetic phase: Absorption correct
answers >> (small intestine) the movement of a
drug from its site of administration into the blood
pharmacokinetic phase: Distribution correct
answers >> drug moves from blood --> cell
membrane
pharmacokinetic phase:
Metabolism/biotransformation correct answers
>> lipid soluble metabolite (liver) --> a water
soluble metabolite
pharmacokinetic phase: Excretion correct
answers >> water soluble metabolite (kidneys)
liver correct answers >> breaks down the drug
kidneys correct answers >> excretes the drug
Pharmacokinetic phase movement process
correct answers >> orally --> stomach --> SI -->
bloodstream --> site of action --> liver (broken
down) --> kidneys (excreted)
GRADED A+
, IV --> bloodstream --> cite of action --> liver -->
kidneys
drugs crossing the cell membranes phospholipid
cell layer correct answers >> -drugs must be
LIPID SOLUBLE in order to pass through the
membrane
- WATER SOLUBLE drugs penetrate the cell
membrane through channels and pores
Absorption
1. direct penetration of the membranes
2. channels and pores
3. transport systems correct answers >> the
movement of a drug from its site of administration
to the blood
How do drugs cross membranes?
GRADED A+
PHARMACOLOGY PRINCIPLES
NUR 210 EXAM 1|2025-2026
LATEST VERSION|
COMPREHENSIVE QUESTIONS
AND VERIFIED
ANSWERS/ACCURATE
SOLUTIONS|ALREADY
GRADED A+
drug response correct answers >> the intensity
of the drug response is directly related to the
concentration of the drug at the SITE OF ACTION
Goal is to:
- maximize the beneficial effects- concentration
high enough for desired response
- minimize harm- avoid to high a concentration
GRADED A+
,Three phases of drug action correct answers >>
1. pharmaceutic phase (dissolution)
2. pharmacokinetic phase (drug moving through
the body)
3. pharmacodynamic phase (what the drug does to
the body)
1. pharmaceutic phase correct answers >> the
drug goes into solution
- Dissolution: the process by which a drug goes into
solution and becomes available for absorption
- must be dissolved before it can be absorbed
- most absorption takes place in the small intestine
2. pharmacokinetic phase: four processes correct
answers >> "what the BODY does to the drug"
- absorption
- distribution
- metabolism/ biotransformation
- exertion
GRADED A+
,pharmacokinetic phase: Absorption correct
answers >> (small intestine) the movement of a
drug from its site of administration into the blood
pharmacokinetic phase: Distribution correct
answers >> drug moves from blood --> cell
membrane
pharmacokinetic phase:
Metabolism/biotransformation correct answers
>> lipid soluble metabolite (liver) --> a water
soluble metabolite
pharmacokinetic phase: Excretion correct
answers >> water soluble metabolite (kidneys)
liver correct answers >> breaks down the drug
kidneys correct answers >> excretes the drug
Pharmacokinetic phase movement process
correct answers >> orally --> stomach --> SI -->
bloodstream --> site of action --> liver (broken
down) --> kidneys (excreted)
GRADED A+
, IV --> bloodstream --> cite of action --> liver -->
kidneys
drugs crossing the cell membranes phospholipid
cell layer correct answers >> -drugs must be
LIPID SOLUBLE in order to pass through the
membrane
- WATER SOLUBLE drugs penetrate the cell
membrane through channels and pores
Absorption
1. direct penetration of the membranes
2. channels and pores
3. transport systems correct answers >> the
movement of a drug from its site of administration
to the blood
How do drugs cross membranes?
GRADED A+