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• 2025 NURS 6230 Advanced Pathophysiology Exam – Midterm Test Questions

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• 2025 NURS 6230 Advanced Pathophysiology Exam – Midterm Test Questions

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1. What is the primary cause of atherosclerosis?
A. Decreased calcium intake
B. Chronic inflammation of the blood vessels
C. Increased HDL cholesterol
D. Vitamin D deficiency
Answer: B) Chronic inflammation of the blood vessels
Rationale: Atherosclerosis is primarily caused by the build-up of
plaque in the arteries, often triggered by chronic inflammation
and high levels of LDL cholesterol in the bloodstream.

2. What is the most common cause of secondary osteoporosis?
A. Calcium deficiency
B. Hyperparathyroidism
C. Long-term use of corticosteroids
D. Vitamin D deficiency
Answer: C) Long-term use of corticosteroids
Rationale: Long-term corticosteroid use is a major cause of
secondary osteoporosis due to its effect on bone metabolism,
leading to decreased bone density and increased fracture risk.

3. Which of the following would you expect in a patient with
Addison’s disease?
A. Increased blood pressure
B. Hyperkalemia
C. Weight gain
D. Increased appetite
Answer: B) Hyperkalemia
Rationale: Addison’s disease, a disorder of the adrenal glands,
leads to decreased cortisol and aldosterone production. This
results in fluid and sodium loss and potassium retention, causing
hyperkalemia.

,4. Which of the following is a common cause of hypoxemia?
A. Anemia
B. Asthma
C. Hypertension
D. Diabetes
Answer: B) Asthma
Rationale: Asthma causes bronchoconstriction and inflammation
in the airways, leading to decreased oxygen exchange and
resulting in hypoxemia.

5. In which condition would you expect to find a low white blood
cell (WBC) count?
A. Viral infection
B. Leukemia
C. Bacterial infection
D. Bone marrow suppression
Answer: D) Bone marrow suppression
Rationale: Bone marrow suppression, often caused by
chemotherapy or certain diseases, can result in low WBC counts
(leukopenia).

6. A patient with hypothyroidism is most likely to have which of
the following symptoms?
A. Weight loss
B. Increased heart rate
C. Cold intolerance
D. Heat intolerance
Answer: C) Cold intolerance
Rationale: Hypothyroidism leads to reduced metabolism, causing
symptoms such as cold intolerance, weight gain, and fatigue.

7. A nurse is caring for a patient with pneumonia. Which of the

, following is a common sign of pneumonia?
A. Cough with sputum production
B. Sudden weight gain
C. Seizures
D. Hemoptysis without cough
Answer: A) Cough with sputum production
Rationale: Pneumonia typically presents with symptoms such as a
productive cough with purulent sputum, fever, and difficulty
breathing due to inflammation in the lungs.

8. What is the main cause of liver cirrhosis?
A. Alcohol abuse
B. High-fat diet
C. Viral infections (e.g., hepatitis B or C)
D. Obesity
Answer: A) Alcohol abuse
Rationale: Chronic alcohol use is the leading cause of cirrhosis,
leading to liver fibrosis and eventual liver failure.

9. A patient with a diagnosis of schizophrenia may experience
which of the following symptoms?
A. Auditory hallucinations
B. Extreme fatigue
C. Increased blood pressure
D. Chronic cough
Answer: A) Auditory hallucinations
Rationale: Schizophrenia is often associated with psychotic
symptoms, including auditory hallucinations, delusions, and
disorganized thinking.

10. A patient with diabetes mellitus presents with polyuria,
polydipsia, and weight loss. What condition might these
symptoms indicate?

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