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• Advanced Pathophysiology Exam 3 (NURS 5350) – 2025 Edition

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• Advanced Pathophysiology Exam 3 (NURS 5350) – 2025 Edition

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1. A patient with acute bacterial meningitis is likely to experience
which of the following?
A. Increased thirst and urination
B. Severe headache and neck stiffness
C. Joint pain and swelling
D. Abdominal pain and bloating
Answer: B) Severe headache and neck stiffness
Rationale: Acute bacterial meningitis causes inflammation of the
meninges, leading to symptoms like severe headache, neck
stiffness, photophobia, and fever.

2. What condition is characterized by the failure of the heart to
pump effectively, leading to inadequate tissue perfusion?
A. Stroke
B. Coronary artery disease (CAD)
C. Heart failure
D. Hypertension
Answer: C) Heart failure
Rationale: Heart failure occurs when the heart is unable to pump
blood efficiently, leading to reduced perfusion of tissues and
organs.

3. What is a classic symptom of Parkinson’s disease?
A. Muscle rigidity
B. Hypotension
C. Polyuria
D. Weight gain
Answer: A) Muscle rigidity
Rationale: Parkinson’s disease is characterized by symptoms such
as muscle rigidity, tremors, and bradykinesia due to a loss of
dopaminergic neurons in the brain.

,4. A nurse is assessing a client with a suspected myocardial
infarction (MI). Which finding would be most indicative of an MI?
A. Severe sharp chest pain that radiates to the left shoulder
B. Shortness of breath with a productive cough
C. Gradual onset of bilateral lower leg edema
D. Sudden dizziness with no associated chest pain
Answer: A) Severe sharp chest pain that radiates to the left
shoulder
Rationale: A common symptom of myocardial infarction is chest
pain that radiates to the left shoulder or arm. This is due to
ischemia affecting the heart muscle.

5. A patient presents with a chronic cough, wheezing, and
shortness of breath. Which condition should the nurse suspect?
A. Bronchitis
B. Emphysema
C. Asthma
D. Pulmonary embolism
Answer: C) Asthma
Rationale: Asthma is characterized by inflammation and
constriction of the airways, leading to symptoms like chronic
cough, wheezing, and difficulty breathing.

6. A patient with acute blood loss from a traumatic injury may
experience which of the following?
A. Decreased heart rate
B. Decreased respiratory rate
C. Increased blood pressure
D. Increased heart rate
Answer: D) Increased heart rate
Rationale: Acute blood loss leads to a decrease in circulating
blood volume, which triggers compensatory tachycardia

, (increased heart rate) to maintain cardiac output.

7. What is the main cause of liver cirrhosis?
A. Alcohol abuse
B. High-fat diet
C. Viral infections (e.g., hepatitis B or C)
D. Obesity
Answer: A) Alcohol abuse
Rationale: Chronic alcohol use is the leading cause of cirrhosis,
leading to liver fibrosis and eventual liver failure.

8. Which of the following is a classic sign of hyperthyroidism?
A. Weight gain
B. Cold intolerance
C. Tachycardia
D. Bradycardia
Answer: C) Tachycardia
Rationale: Hyperthyroidism is characterized by an overproduction
of thyroid hormones, leading to symptoms like tachycardia, heat
intolerance, and weight loss.

9. What is the most common cause of secondary osteoporosis?
A. Calcium deficiency
B. Hyperparathyroidism
C. Long-term use of corticosteroids
D. Vitamin D deficiency
Answer: C) Long-term use of corticosteroids
Rationale: Long-term corticosteroid use is a major cause of
secondary osteoporosis due to its effect on bone metabolism,
leading to decreased bone density and increased fracture risk.

10. A patient presents with fever, jaundice, and dark urine. Which
condition might this indicate?

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