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• 2025 NURS 6230 Advanced Pathophysiology Midterm Review Guide

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• 2025 NURS 6230 Advanced Pathophysiology Midterm Review Guide

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1. A patient with acute blood loss from a traumatic injury may
experience which of the following?
A. Decreased heart rate
B. Decreased respiratory rate
C. Increased blood pressure
D. Increased heart rate
Answer: D) Increased heart rate
Rationale: Acute blood loss leads to a decrease in circulating
blood volume, which triggers compensatory tachycardia
(increased heart rate) to maintain cardiac output.

2. What is the main cause of type 2 diabetes?
A. Insulin resistance
B. Insulin deficiency
C. Autoimmune destruction of beta cells
D. Excessive glucagon secretion
Answer: A) Insulin resistance
Rationale: Type 2 diabetes is primarily caused by insulin
resistance, where the body’s cells do not respond effectively to
insulin, leading to elevated blood glucose levels.

3. A patient presents with a chronic cough, wheezing, and
shortness of breath. Which condition should the nurse suspect?
A. Bronchitis
B. Emphysema
C. Asthma
D. Pulmonary embolism
Answer: C) Asthma
Rationale: Asthma is characterized by inflammation and
constriction of the airways, leading to symptoms like chronic
cough, wheezing, and difficulty breathing.

,4. A patient has been diagnosed with tuberculosis (TB). Which of
the following is the most common symptom?
A. Night sweats
B. Joint pain
C. Hematuria
D. Abdominal pain
Answer: A) Night sweats
Rationale: Night sweats are a classic symptom of tuberculosis,
along with cough and weight loss.

5. A nurse is caring for a patient with rheumatoid arthritis. Which
of the following is a common manifestation of this condition?
A. Symmetrical joint pain and swelling
B. Morning dizziness and fatigue
C. Unilateral leg swelling
D. Chest pain
Answer: A) Symmetrical joint pain and swelling
Rationale: Rheumatoid arthritis typically causes symmetrical joint
pain, stiffness, and swelling, particularly in the hands and feet.

6. In which condition would you expect to find a low white blood
cell (WBC) count?
A. Viral infection
B. Leukemia
C. Bacterial infection
D. Bone marrow suppression
Answer: D) Bone marrow suppression
Rationale: Bone marrow suppression, often caused by
chemotherapy or certain diseases, can result in low WBC counts
(leukopenia).

7. A patient with a diagnosis of schizophrenia may experience

, which of the following symptoms?
A. Auditory hallucinations
B. Extreme fatigue
C. Increased blood pressure
D. Chronic cough
Answer: A) Auditory hallucinations
Rationale: Schizophrenia is often associated with psychotic
symptoms, including auditory hallucinations, delusions, and
disorganized thinking.

8. What is the most common cause of secondary hypertension?
A. Excessive salt intake
B. Renal disease
C. High cholesterol levels
D. Alcohol consumption
Answer: B) Renal disease
Rationale: Secondary hypertension is often caused by another
condition, with renal disease being a leading factor due to
impaired kidney function affecting fluid balance and blood
pressure regulation.

9. Which of the following is a common cause of hypoxemia?
A. Anemia
B. Asthma
C. Hypertension
D. Diabetes
Answer: B) Asthma
Rationale: Asthma causes bronchoconstriction and inflammation
in the airways, leading to decreased oxygen exchange and
resulting in hypoxemia.

10. What is a classic symptom of Parkinson’s disease?
A. Muscle rigidity

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