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• 2025 NURS 6230 Midterm Advanced Pathophysiology Exam Guide

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• 2025 NURS 6230 Midterm Advanced Pathophysiology Exam Guide

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1. A patient with chronic kidney disease (CKD) is most at risk for
which of the following electrolyte imbalances?
A. Hyperkalemia
B. Hypokalemia
C. Hypercalcemia
D. Hypocalcemia
Answer: A) Hyperkalemia
Rationale: In CKD, the kidneys are unable to excrete potassium
effectively, leading to the accumulation of potassium in the blood,
resulting in hyperkalemia.

2. Which of the following is a primary complication of untreated
hypertension?
A. Diabetes
B. Stroke
C. Asthma
D. Hyperthyroidism
Answer: B) Stroke
Rationale: Untreated hypertension can cause damage to blood
vessels, increasing the risk of a stroke due to the development of
atherosclerosis or rupture of a weakened vessel.

3. What is the most common cause of secondary hypertension?
A. Excessive salt intake
B. Renal disease
C. High cholesterol levels
D. Alcohol consumption
Answer: B) Renal disease
Rationale: Secondary hypertension is often caused by another
condition, with renal disease being a leading factor due to
impaired kidney function affecting fluid balance and blood

,pressure regulation.

4. A patient with acute blood loss from a traumatic injury may
experience which of the following?
A. Decreased heart rate
B. Decreased respiratory rate
C. Increased blood pressure
D. Increased heart rate
Answer: D) Increased heart rate
Rationale: Acute blood loss leads to a decrease in circulating
blood volume, which triggers compensatory tachycardia
(increased heart rate) to maintain cardiac output.

5. A patient with a history of chronic pancreatitis is at increased
risk for which of the following complications?
A. Diabetes mellitus
B. Hypoglycemia
C. Hyperkalemia
D. Asthma
Answer: A) Diabetes mellitus
Rationale: Chronic pancreatitis can damage the pancreas' ability
to secrete insulin, leading to insulin resistance and an increased
risk of diabetes mellitus.

6. Which of the following would you expect in a patient with
Addison’s disease?
A. Increased blood pressure
B. Hyperkalemia
C. Weight gain
D. Increased appetite
Answer: B) Hyperkalemia
Rationale: Addison’s disease, a disorder of the adrenal glands,
leads to decreased cortisol and aldosterone production. This

, results in fluid and sodium loss and potassium retention, causing
hyperkalemia.

7. Which of the following is a common sign of hypovolemic
shock?
A. Bradycardia
B. Tachycardia
C. Warm skin
D. Hypertension
Answer: B) Tachycardia
Rationale: In hypovolemic shock, blood volume decreases, and the
body compensates by increasing the heart rate (tachycardia) to
maintain blood flow to vital organs.

8. Which of the following is the most likely cause of anaphylactic
shock?
A. Blood loss
B. Allergic reaction
C. Bacterial infection
D. Spinal cord injury
Answer: B) Allergic reaction
Rationale: Anaphylactic shock is a severe allergic reaction that
causes vasodilation and fluid leakage, leading to hypotension and
shock.

9. A nurse is assessing a client with a suspected myocardial
infarction (MI). Which finding would be most indicative of an MI?
A. Severe sharp chest pain that radiates to the left shoulder
B. Shortness of breath with a productive cough
C. Gradual onset of bilateral lower leg edema
D. Sudden dizziness with no associated chest pain
Answer: A) Severe sharp chest pain that radiates to the left
shoulder

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