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MCB4271 FINAL EXAM 2025 | MOLECULAR AND CELL BIOLOGY
EXAM | UPDATED QUESTIONS AND ANSWERS | GRADED A+ |
VERIFIED ANSWERS (JUST RELEASED)
Which of the following antibiotics can be inactivated by beta-
lactamases? - ANSWER-ampicillin, penicillin, cephalosporin
What is the functional consequence of drugs that inhibit the
generation of muropeptides? - ANSWER-an increase in
efficiencies of beta-lactam antibiotics
Efflux pumps permit diffusion of molecules across the plasma
membrane. Hence, they do not require energy. - ANSWER-False
Which of the following statements best describes porins -
ANSWER-provide the first line of defense against toxic
compounds
E. coli efflux pumps increase MIC of antibiotics - ANSWER-
increase
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What are some of the factors contributing to clinical resistance? -
ANSWER-type of bacteria, infection site, antibiotic pharmokinetics
In 1942, penicillin became commercially available. First official
signs of penicillin resistance mechanism were observed: -
ANSWER-in 1940 by Abraham and Chain
MIC stands for - ANSWER-minimum inhibitory concentration
What of the following is an example of antibiotic target
modification - ANSWER-23s rRNA mutation of the 50S ribosomal
subunit, D-ala-D-ala to D-ala-D-lac substitution, positively
charging envelope
Which of the following is not an example of antibiotic target
modification? - ANSWER-drug linearization
Bacteria gain resistance to trimethoprim mainly by which of the
following mechanisms? - ANSWER-mutation in DHFR?
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Biofilms are _____. Check all that apply - ANSWER-resistant to
antibiotics, resistant to antiseptics
What are planktonic bacteria? - ANSWER-single cells floating in
liquid
What does VRE stand for? - ANSWER-Vancomycin resistant
Enterococci
Staphylococcus aureus is the cause of the most common
hospital-acquired infections - ANSWER-True
ESKAPE pathogens attack only immunocompromised individuals
- ANSWER-False
What do all ESKAPE pathogens have in common? - ANSWER-
Highly resistant, transmissible, pathogenic
Which of the following statements is NOT true? - ANSWER-The
clinical ecosystem is the major reservoir of AMR
MCB4271 FINAL EXAM 2025 | MOLECULAR AND CELL BIOLOGY
EXAM | UPDATED QUESTIONS AND ANSWERS | GRADED A+ |
VERIFIED ANSWERS (JUST RELEASED)
Which of the following antibiotics can be inactivated by beta-
lactamases? - ANSWER-ampicillin, penicillin, cephalosporin
What is the functional consequence of drugs that inhibit the
generation of muropeptides? - ANSWER-an increase in
efficiencies of beta-lactam antibiotics
Efflux pumps permit diffusion of molecules across the plasma
membrane. Hence, they do not require energy. - ANSWER-False
Which of the following statements best describes porins -
ANSWER-provide the first line of defense against toxic
compounds
E. coli efflux pumps increase MIC of antibiotics - ANSWER-
increase
,2|Page
What are some of the factors contributing to clinical resistance? -
ANSWER-type of bacteria, infection site, antibiotic pharmokinetics
In 1942, penicillin became commercially available. First official
signs of penicillin resistance mechanism were observed: -
ANSWER-in 1940 by Abraham and Chain
MIC stands for - ANSWER-minimum inhibitory concentration
What of the following is an example of antibiotic target
modification - ANSWER-23s rRNA mutation of the 50S ribosomal
subunit, D-ala-D-ala to D-ala-D-lac substitution, positively
charging envelope
Which of the following is not an example of antibiotic target
modification? - ANSWER-drug linearization
Bacteria gain resistance to trimethoprim mainly by which of the
following mechanisms? - ANSWER-mutation in DHFR?
, 3|Page
Biofilms are _____. Check all that apply - ANSWER-resistant to
antibiotics, resistant to antiseptics
What are planktonic bacteria? - ANSWER-single cells floating in
liquid
What does VRE stand for? - ANSWER-Vancomycin resistant
Enterococci
Staphylococcus aureus is the cause of the most common
hospital-acquired infections - ANSWER-True
ESKAPE pathogens attack only immunocompromised individuals
- ANSWER-False
What do all ESKAPE pathogens have in common? - ANSWER-
Highly resistant, transmissible, pathogenic
Which of the following statements is NOT true? - ANSWER-The
clinical ecosystem is the major reservoir of AMR
