NURS 615 Pharm Exam 1 – Maryville Questions with Correct Answers 2025

NURS 615 Pharm Exam 1 – Maryville
Questions with Correct Answers 2025

HowBdoesBhypoalbuminemiaBaffectBtheBprocessBofBprescribing?B-BCORRECTBANSWERB-
LowBalbuminB=BmoreBfreeBdrugB(bcBtheBdrugBcan'tBbindBtoBalbuminBakaBprotein)B=BincreasedBadver
seBeffects



WhatBisBaBBlackBBoxBWarning:B-BCORRECTBANSWERB-
isBconsideredBaBcontraindicationBtoBadministerBthatBdrug.



WhatBisBtheBdrugsBhalf-life?B-BCORRECTBANSWERB-Half-
lifeBspecificallyBmeansBtheBamountBofBtimeBitBtakesBforBanBadministeredBdrugBtoBbeBhalfwayBcleare
dBfromBtheBsystem.



PeakBofBaction:B-BCORRECTBANSWERB-
theBtimeBbetweenBdrugBadministrationBandBmaximumBconcentrationBofBdrugBinBtheBbloodBstream.
BBestBtherapeuticBeffect.




DurationBofBaction:B-BCORRECTBANSWERB-
theBtimeBbetweenBonsetBofBactionBandBmetabolismBofBdrugBbelowBtheBminimumBneededBforBanBef
fect.BTheBlengthBofBtimeByouBhaveBtheBdrugBinByourBsystem.



AccordingBtoBtheBWHOBwhatBisBtheBfirstBstepBinBtheBprescribingBprocess?B-BCORRECTBANSWERB-
TheBfirstBstepBisBtoBdefineBtheBpatient'sBproblem



TheBsecondBstepBisBtoB-BCORRECTBANSWERB-specifyBtheBtherapeuticBobjective



TheBthirdBstepBisBtoB-BCORRECTBANSWERB-chooseBwhichBdrugBorBtreatmentBisBneeded.

,StepB4BofBtheBWHOBapproach:B-BCORRECTBANSWERB-StartBtheBtreatment



StepB5BofBtheBWHOBapproach:B-BCORRECTBANSWERB-EducateBtheBpatient



StepB6BofBtheBWHOBapproach:B-BCORRECTBANSWERB-MonitorBtheBtreatment



PhaseB1BofBdrugBdevelopment:B-BCORRECTBANSWERB-TheBdrugBisBtestedBonBhealthyBvolunteers



PhaseB2BofBdrugBdevelopment:B-BCORRECTBANSWERB-
trialsBwithBpeopleBwhoBhaveBtheBdiseaseBforBwhichBtheBdrugBisBthoughtBtoBbeBeffective



PhaseB3BofBdrugBdevelopment:B-BCORRECTBANSWERB-
LargeBnumbersBofBpatientsBinBmedicalBresearchBcentersBreceiveBtheBdrugBinBphaseB3.BThisBlargerBsa
mplingBprovidesBinformationBaboutBinfrequentBorBrareBadverseBeffects.BTheBFFABwillBapproveBaBne
wBdrugBapplicationBifBphaseB3BstudiesBareBsatisfactory.



PhaseB4BofBdrugBdevelopment:B-BCORRECTBANSWERB-
ThisBphaseBisBvoluntaryBandBinvolvesBpostmarketBsurveillanceBofBtheBdrug'sBtherapeuticBeffectsBatB
theBcompletionBofBphaseB3.BTheBpharmaceuticalBcompanyBreceivesBreportsBfromBdoctorsBandBoth
erBhealthBcareBprofessionalsBaboutBtheBtherapeuticBresultsBandBadverseBeffectsBofBtheBdrug.BSome
Bmedications,BforBexample,BhaveBbeenBfoundBtoBbeBtoxicBandBhaveBbeenBremovedBfromBtheBmarke


tBafterBtheirBinitialBrelease.



ExplainBfirstBpassBmetabolismB-BCORRECTBANSWERB-
muchBofBtheBdrugBisBlostBinBtheBabsorptionBprocess.BTheBliverBmetabolizesBmanyBdrugs,BthusBreduc
esBtheBbioavailabiltyBofBtheBdrug.

, WhatBisBtheBfastedBrouteBofBabsorption:B-BCORRECTBANSWERB-
TheBfastestBrouteBofBabsorptionBisBinhalation,BandBnotBasBmistakenlyBconsideredBtheBIVBadministra
tion.



WhyBdoesBtheBGIBtractBtakeBlongerBtoBabsorb?B-BCORRECTBANSWERB-
TheBGIBtractBisBlinedBwithBepithelialBcells;BdrugsBmustBpermeateBthroughBtheseBcellsBinBorderBtoBbe
BabsorbedBintoBtheBcirculatoryBsystem.




WhatBisBOneBparticularBcellularBbarrierBthatBmayBpreventBabsorptionBofBaBgivenBdrug?B-
BCORRECTBANSWERB-


theBcellBmembrane.BCellBmembranesBareBessentiallyBlipidBbilayersBwhichBformBaBsemipermeableB
membrane.BPureBlipidBbilayersBareBgenerallyBpermeableBonlyBtoBsmallBandBunchargedBsolutes,Bhe
nceBwhetherBorBnotBaBmoleculeBisBionizedBwillBaffectBitsBabsorption,BsinceBionicBmoleculesBareBcha
rged.



WhatBisBsolubility?B-BCORRECTBANSWERB-
SolubilityBfavorsBchargedBspecies,BpermeabilityBfavorsBneutralBspecies.BSomeBmoleculesBhaveBspe
cialBexchangeBproteinsBandBchannelsBtoBfacilitateBmovementBfromBtheBlumenBintoBtheBcirculation.



WhyBdoesBabsorptionBoccurBatBaBslowerBrateBforBoral,BIM,BSQBroutes?B-BCORRECTBANSWERB-
AbsorptionBoccursBatBaBslowerBrateBbecauseBtheBcomplexBmembraneBsystemsBofBGIBmucosalBlayer
s,Bmuscle,BandBskinBdelayBdrugBpassage.



TheBabilityBofBaBdrugBtoBcrossBaBcellBmembraneBdependsBon:B-BCORRECTBANSWERB-
whetherBtheBdrugBisBwaterBorBlipidB(fat)Bsoluble.BLipid-
solubleBdrugsBeasilyBcrossBthroughBcellBmembranes;Bwater-solubleBdrugsBcan't.BLipid-
solubleBdrugsBcanBalsoBcrossBtheBblood-brainBbarrierBandBenterBtheBbrain.



AsBaBdrugBtravelsBthroughBtheBbody,BitBcomesBinBcontactBwith?B-BCORRECTBANSWERB-
proteinsBsuchBasBtheBplasmaBproteinBalbumin.BTheBdrugBcanBremainBfreeBorBbindBtoBtheBprotein.BT
heBportionBofBaBdrugBthat'sBboundBtoBaBproteinBisBinactiveBandBcan'tBexertBaBtherapeuticBeffect.BOnl