ASCP Blood bank UPDATED Exam
Questions and CORRECT Answers
The use of the direct antiglobulin test is indicated in all the following EXCEPT: - CORRECT
ANSWER - Detection of alloantibodies in serum
Which one of the following blood group systems may show a cell typing change during
pregnancy? - CORRECT ANSWER - Lewis
What is the deferral period from donating blood for someone who is or has taken Tegison© for
severe psoriasis? - CORRECT ANSWER - Permanent deferral
Both hemoglobinuria and hemoglobinemia will be present in what type of reactions? -
CORRECT ANSWER - Acute hemolytic transfusion reactions
If the unit is going to be transfused within the collection facility, autologous blood must always
be tested for which of the following before transfusion? - CORRECT ANSWER - ABO,
Rh
Which of the following statements about high-frequency antigens is correct? - CORRECT
ANSWER - High-frequency antigens are common, but it is difficult to identify their
corresponding antibodies.
The immunoglobulin class responsible for the etiology of Hemolytic Disease of the Fetus and
Newborn (HDFN) is: - CORRECT ANSWER - IgG
Before testing, all cord cells should be thoroughly washed in order to: - CORRECT
ANSWER - Remove Wharton's jelly
An antibody screen utilizing polyethylene glycol (PEG) was performed. Reaction readings of
this antibody screen are analyzed after immediate spin and again at 37°C incubation with
,subsequent centrifugation. How will the centrifugation of the tubes affect the patient's results? -
CORRECT ANSWER - False positives may be seen
Which best describes an A1 individual? - CORRECT ANSWER - A and A1 antigens on
RBCs and anti-B antibodies in serum.
Platelet products will be prepared from a whole blood donation. What must be used to prevent
potential contamination of the platelets with skin cells and bacteria? - CORRECT
ANSWER - Diversion pouch
Which procedure used to obtain a fetal blood sample to monitor severity of hemolytic disease of
the fetus and newborn (HDFN) can also be used to deliver intrauterine transfusions? -
CORRECT ANSWER - Cordocentesis
One risk associated with patients that require chronic transfusions is: - CORRECT
ANSWER - Transfusion associated graft-versus-host disease (TA-GVHD)
What is the principle of the Kleihauer-Betke test? - CORRECT ANSWER - Fetal cells
present in the mother's blood smear contain fetal hemoglobin (Hgb F). When treated with acid
the fetal cells are resistant and will stain pink with the counter stain.
The accepted interval between whole blood donations is: - CORRECT ANSWER -8
weeks
How long after collection can a patient's sample be used for compatibility testing? - CORRECT
ANSWER - 72 hours
What is the rare phenotype found exclusively in male patients that is caused by X-linked
inheritance from a carrier mother, often demonstrating a chronic but well-compensated anemia
as well as muscle and nerve disorders? - CORRECT ANSWER - McLeod
, Why is Rh immune globulin (RhIg) administered within 72 hours of delivery to an Rh negative
mother if the newborn is found to be D-positive or weak-D positive? - CORRECT
ANSWER - Prevent fetal cells from initially sensitizing the mother
Which of the following consequences of severe hemolytic disease of the fetus and newborn
(HDFN) is most associated with neonatal death before or shortly after birth? - CORRECT
ANSWER - Cardiac failure
Following a major trauma event, a family of four walks into your donor center hoping to donate
blood. Which one of the following individuals may donate blood today? - CORRECT
ANSWER - A 22-year-old woman using oral contraceptives.
Which of the following is the most common type of autoimmune hemolytic anemia? -
CORRECT ANSWER - Paroxysmal cold hemoglobinuria.
All of the following are advantages of performing the computer crossmatch EXCEPT? -
CORRECT ANSWER - One determination of recipient's ABO group is made
Which of the following can be used to confirm if someone has the Bombay phenotype? -
CORRECT ANSWER - Ulex europaeus
Which of the following antigen groups is closely related to the ABO antigens on the red cell
membrane? - CORRECT ANSWER - I, i
What additional information is required on a label or tie tag of an autologous unit? - CORRECT
ANSWER - Identification of the recipient
When giving a whole blood donation to a patient, what consideration must be made in regards to
the ABO/Rh compatibility between the recipient and the donor? - CORRECT ANSWER -
The recipient and donor ABO and Rh types must be identical.
Questions and CORRECT Answers
The use of the direct antiglobulin test is indicated in all the following EXCEPT: - CORRECT
ANSWER - Detection of alloantibodies in serum
Which one of the following blood group systems may show a cell typing change during
pregnancy? - CORRECT ANSWER - Lewis
What is the deferral period from donating blood for someone who is or has taken Tegison© for
severe psoriasis? - CORRECT ANSWER - Permanent deferral
Both hemoglobinuria and hemoglobinemia will be present in what type of reactions? -
CORRECT ANSWER - Acute hemolytic transfusion reactions
If the unit is going to be transfused within the collection facility, autologous blood must always
be tested for which of the following before transfusion? - CORRECT ANSWER - ABO,
Rh
Which of the following statements about high-frequency antigens is correct? - CORRECT
ANSWER - High-frequency antigens are common, but it is difficult to identify their
corresponding antibodies.
The immunoglobulin class responsible for the etiology of Hemolytic Disease of the Fetus and
Newborn (HDFN) is: - CORRECT ANSWER - IgG
Before testing, all cord cells should be thoroughly washed in order to: - CORRECT
ANSWER - Remove Wharton's jelly
An antibody screen utilizing polyethylene glycol (PEG) was performed. Reaction readings of
this antibody screen are analyzed after immediate spin and again at 37°C incubation with
,subsequent centrifugation. How will the centrifugation of the tubes affect the patient's results? -
CORRECT ANSWER - False positives may be seen
Which best describes an A1 individual? - CORRECT ANSWER - A and A1 antigens on
RBCs and anti-B antibodies in serum.
Platelet products will be prepared from a whole blood donation. What must be used to prevent
potential contamination of the platelets with skin cells and bacteria? - CORRECT
ANSWER - Diversion pouch
Which procedure used to obtain a fetal blood sample to monitor severity of hemolytic disease of
the fetus and newborn (HDFN) can also be used to deliver intrauterine transfusions? -
CORRECT ANSWER - Cordocentesis
One risk associated with patients that require chronic transfusions is: - CORRECT
ANSWER - Transfusion associated graft-versus-host disease (TA-GVHD)
What is the principle of the Kleihauer-Betke test? - CORRECT ANSWER - Fetal cells
present in the mother's blood smear contain fetal hemoglobin (Hgb F). When treated with acid
the fetal cells are resistant and will stain pink with the counter stain.
The accepted interval between whole blood donations is: - CORRECT ANSWER -8
weeks
How long after collection can a patient's sample be used for compatibility testing? - CORRECT
ANSWER - 72 hours
What is the rare phenotype found exclusively in male patients that is caused by X-linked
inheritance from a carrier mother, often demonstrating a chronic but well-compensated anemia
as well as muscle and nerve disorders? - CORRECT ANSWER - McLeod
, Why is Rh immune globulin (RhIg) administered within 72 hours of delivery to an Rh negative
mother if the newborn is found to be D-positive or weak-D positive? - CORRECT
ANSWER - Prevent fetal cells from initially sensitizing the mother
Which of the following consequences of severe hemolytic disease of the fetus and newborn
(HDFN) is most associated with neonatal death before or shortly after birth? - CORRECT
ANSWER - Cardiac failure
Following a major trauma event, a family of four walks into your donor center hoping to donate
blood. Which one of the following individuals may donate blood today? - CORRECT
ANSWER - A 22-year-old woman using oral contraceptives.
Which of the following is the most common type of autoimmune hemolytic anemia? -
CORRECT ANSWER - Paroxysmal cold hemoglobinuria.
All of the following are advantages of performing the computer crossmatch EXCEPT? -
CORRECT ANSWER - One determination of recipient's ABO group is made
Which of the following can be used to confirm if someone has the Bombay phenotype? -
CORRECT ANSWER - Ulex europaeus
Which of the following antigen groups is closely related to the ABO antigens on the red cell
membrane? - CORRECT ANSWER - I, i
What additional information is required on a label or tie tag of an autologous unit? - CORRECT
ANSWER - Identification of the recipient
When giving a whole blood donation to a patient, what consideration must be made in regards to
the ABO/Rh compatibility between the recipient and the donor? - CORRECT ANSWER -
The recipient and donor ABO and Rh types must be identical.
