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Exam (elaborations)

Pathophys Exam 1 Lecture 4 and 5

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What is the typical cardiac output at rest? About 4 to 6 L/min at rest. It matches the demand of the body, as demand goes up (exercising) CO goes up 5-6 x more What is cardiac reserve? Cardiac reserve is the difference between a person's maximum and resting cardiac output. Increases with fitness, decreases with disease (can decrease to 0 in some disease states) What are the three variables that govern stroke volume? Preload (I.e. end diastolic volume, ~120 mL) Contractility Afterload (resistance (HTN, aortic stenosis))


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