MCB4271 Exam 3 Study Questions with
Verified Solutions 2025
Surveillance -Correct Answer ✔Allows us to better understand and respond to AMR
patterns and key drivers, information about incidence, prevalence and trends
Purpose of surveillance -Correct Answer ✔Determine the scope of the problem,
formulate effective responses to AMR, and monitor effectiveness of response to AMR
Conclusion about surveillance -Correct Answer ✔There are many gaps in information on
pathogens of major concern, surveillance isn't coordinated or harmonized, many
common treatment options for bacterial infections are becoming ineffective, ABR has
negative impact on outcomes for affected patients and healthcare expenditures, high
levels of resistance have been observed in bacteria that cause common HA and CA
across all WHO regions
Surveillance models -Correct Answer ✔We can use TB, malaria and HIV as models to
determine disease burdens and interventions
Assessment -Correct Answer ✔Diagnostic tools that identify resistance mechanisms and
determine sensitivity to antibiotics
Global Antimicrobial Resistance Surveillance System (GLASS) -Correct Answer ✔Goal is
to enable standardized, comparable and validated data on AMR to be collected, analyzed
and shared with countries in order to inform decision-making, drive local, national and
regional action, and provide evidence for action and advocacy
GLASS Objectives -Correct Answer ✔Foster national surveillance systems and
harmonized global standards, estimate extent and burden of AMR globally by selected
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indicators, analyze and report global data on AMR on a regular basis, detect emerging
resistance and international spread, inform implementation of targeted prevention and
control programs, and assess impacts of interventions
Surveillance Site -Correct Answer ✔Collect basic demographic, clinical, epidemiological
and microbiological information from patients
National Reference Library -Correct Answer ✔Promote good lab practices and support
labs in national surveillance system
National Coordinating Center -Correct Answer ✔Establish and oversee national
surveillance program; gathers national AMR data and communicates with GLASS
GLASS Important Data -Correct Answer ✔Priority pathogens- E. Coli, K. pneumoniae,
acinetobacter spp., S. aureus, S. pneumoniae, salmonella spp., shigella spp., Neisseria
gonorrhoeae
Specimen types- blood, urine, stool, genital swab
Global Antimicrobial Resistance Surveillance System -Correct Answer ✔WHO initiated it;
early implementation stage was 2016-2019 and the majority of countries are still not
registered and many don't report (funding and resources are limited)... surveillance can
even be difficult at the national level
Clinical and Laboratory Standards Institute -Correct Answer ✔Formerly the National
Committee for Clinical Laboratory Standards and it is a international organization with
over 60 countries that does test standardization and monitors test quality
Antibiotic Prescription Numbers -Correct Answer ✔Out of the 40 Million people annually
prescribed antibiotics, 27 Million get antibiotics unnecessarily
MCB4271