Compensatory Mechanisms to Correct Fluid Overload
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Natriuretic Peptide System (NPS)
If water is pathologically gained by the body, or protein is lost, the concentration of
the plasma space (blood) _______________, and this causes a blood to tissue fluid shift.
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Decreases
Causes of Hypoproteinemia
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Diminished protein production (liver diseases like cirrhosis), diminished
protein intake (kwashiorkor), or plasma protein loss (glomerulonephritis).
A person's body, left alone, will institute RAAS to help with dehydration. But if we
were to step in with a medical intervention for someone with water loss and high
osmolality (hyperosmolality), which IV bag would you choose as best to begin the
patient's return to osmolar homeostasis?
a) 3% NS
b) A hypertonic bag
c) A gin and tonic bag
d) 0.45% NS
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d) 0.45% NS
S/S caused by tissue to blood fluid shift:
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, Dehydration (fluid volume deficit); dry mucous membranes, poor skin
turgor, sunken eyes, sunken fontanels in babies, oliguria (diminished urine
output), increased urine concentration, low BP (if dehydration is bad
enough), and acute CNS changes (restlessness, confusion,
unconsciousness, convulsions).
Osmosis
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Diffusion of water through a selectively permeable membrane.
A patient has a disease process; labs show osmolality of 305 (normal osmolality range
= 280-295). Which compartment is more concentrated in the beginning - blood or
tissue? Which is hyperosmolar? Which way will water shift?
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Blood; blood; the water will shift from tissue to blood (moving low to high
concentration).
Where is renin produced?
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The kidneys
Give this one a try later!
Natriuretic Peptide System (NPS)
If water is pathologically gained by the body, or protein is lost, the concentration of
the plasma space (blood) _______________, and this causes a blood to tissue fluid shift.
,Give this one a try later!
Decreases
Causes of Hypoproteinemia
Give this one a try later!
Diminished protein production (liver diseases like cirrhosis), diminished
protein intake (kwashiorkor), or plasma protein loss (glomerulonephritis).
A person's body, left alone, will institute RAAS to help with dehydration. But if we
were to step in with a medical intervention for someone with water loss and high
osmolality (hyperosmolality), which IV bag would you choose as best to begin the
patient's return to osmolar homeostasis?
a) 3% NS
b) A hypertonic bag
c) A gin and tonic bag
d) 0.45% NS
Give this one a try later!
d) 0.45% NS
S/S caused by tissue to blood fluid shift:
Give this one a try later!
, Dehydration (fluid volume deficit); dry mucous membranes, poor skin
turgor, sunken eyes, sunken fontanels in babies, oliguria (diminished urine
output), increased urine concentration, low BP (if dehydration is bad
enough), and acute CNS changes (restlessness, confusion,
unconsciousness, convulsions).
Osmosis
Give this one a try later!
Diffusion of water through a selectively permeable membrane.
A patient has a disease process; labs show osmolality of 305 (normal osmolality range
= 280-295). Which compartment is more concentrated in the beginning - blood or
tissue? Which is hyperosmolar? Which way will water shift?
Give this one a try later!
Blood; blood; the water will shift from tissue to blood (moving low to high
concentration).
Where is renin produced?
Give this one a try later!
The kidneys
