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Psio 305 Keen Quizzes Questions & Answers

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PSIO 305 KEEN QUIZZES QUESTIONS & ANSWERS

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PSIO 305 KEEN QUIZZES QUESTIONS & ANSWERS

To study factors that affect determination of the ectoderm, which of the following could
you do to get a decrease in volume of neural tissue in the developing animal

-- increase the release of nerve growth factor
-- decrease the release of noggin
-- increase the release of chordin
-- decrease the release of bine morphogenic proteins - answers :-- decrease the release
of noggin

The experiment that crossed the nerve from a muscle that had a short contraction time
"a fast muscle" to a muscle w/ a slower contraction profile and from the slower muscle
to the faster muscle demonstrated that the nerve or activity of the muscle had no effect
on properties of the muscle fibers

-- true
-- false - answers :-- false

Which skeletal muscle fiber type requires continuous neural input or activation to retain
its fiber type properties?

-- the pattern and extent of activity throughout life (type of exercise one does) fast twitch
fibers
-- slow twitch fibers - answers :-- slow twitch fibers

Nerve growth factor binds to which type of receptor?

-- receptor serine/threonine kinase
-- receptor guanylyl cyclase
-- receptor tyrosine kinase
-- receptor tyrosine phosphatases - answers :-- receptor tyrosine kinase

A rube goldberg device does which of the following

-- is used in biochemistry for mixing reagents
-- is a type of statistical approach to discern if an effect in significant in physiology
-- is used in neurophysiology for current injection into a cell
-- makes a complex approach out of a simple task - answers :-- makes a complex
approach out of a simple task

Most trophic factors work in an endocrine fashion

-- true
-- false - answers :-- false

,The neuromuscular junction is similar to synapses in the cns in that (select all that
apply)

-- a wave of depolarization in the presynaptic terminal opens voltage gated ca++
channels
-- calcium entry through voltage-gated channels in the presynaptic terminal is necessary
for the release of neurotransmitter
-- the neurotransmitter released from the pre-synaptic terminal binds to specific
receptors on the post-synaptic side
-- the release at the neuromuscular junction of acetylcholine results in just a fraction of a
mv depolarization on the post-synaptic membrane which is similar to what is seen at
synapses in the cns - answers :-- a wave of depolarization in the presynaptic terminal
opens voltage gated ca++ channels
-- calcium entry through voltage-gated channels in the presynaptic terminal is necessary
for the release of neurotransmitter
-- the neurotransmitter released from the pre-synaptic terminal binds to specific
receptors on the post-synaptic side

Small amines and amino acids that are released a neurotransmitter tend to have their
effect on the post-synaptic membrane acting through ionotropic receptors

-- true
-- false - answers :-- true

The molecule responsible for aggregation of nicotinic acetylcholine receptors on the
post-synaptic junctional folds of the muscle fiber is

-- hepatocyte growth factor
-- norepinephrine
-- agrin
-- human growth factor - answers :-- agrin

Which of the following is a special piece of the mesoderm that releases neural
inducers?

-- spemann organizer
-- neural organizer
-- bone morphogenic organizer
-- differentiation organizer - answers :-- spemann organizer

Bone morphogenic proteins activate which pathway?

-- calcium-calmodulin pathway
-- protein kinase a pathway
-- neural induction pathway

, -- smad pathway - answers :-- smad pathway

The germ layer that ultimately gives rise to skeletal muscle tissue is the

-- endoderm
-- mesoderm
-- ectoderm - answers :-- mesoderm

Myogenic regulatory factors include all of the following except

-- hepatocyte growth factor
-- myogenic determining factor
-- myogenic factor 5
-- myogenic regulatory factor - answers :-- hepatocyte growth factor

Which is the correct order for the development of muscle tissue?

-- determination, differentiation, proliferation, maturation
-- differentiation, determination, proliferation, maturation
-- determination, proliferation, differentiation, maturation
-- differentiation, proliferation, determination, maturation - answers :-- determination,
proliferation, differentiation, maturation

What type of cells sit outside the sarcolemma of a muscle fiber but below the basement
membrane of the muscle fiber and retain their ability to divide?

-- myotubes
-- myostatin cells
-- satellite cells
-- myoblasts - answers :-- satellite cells

Retrograde signaling or transmission can have a variety of actions that impact the 'pre-
synaptic' neuron. These actions could include which of the following? (select all that
apply)

-- promote cell survival
-- enhance synthesis of the neurotransmitter normally released by that neuron
-- inhibit or reduce the amount of neurotransmitter released
-- impact synaptic efficacy - answers :-- promote cell survival
-- enhance synthesis of the neurotransmitter normally released by that neuron
-- inhibit or reduce the amount of neurotransmitter released
-- impact synaptic efficacy

Botox has become popular for reducing wrinkles. It is a dilute solution of a toxin which
inhibits muscle contraction by working at the presynaptic portion of the nmj. Which of
the following could be a possible mechanism for botox wrinkle-reducing action?

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