NSG4330 Exam | QUESTIONS WITH 100% CORRECT ANSWERS| LATEST UPDATE 100%
VERIFIED
HIV: Pharmacological Treatment Goals:
Decrease viral load and retain CD4+ T cells
Delay symptoms and opportunistic infections
Prevent transmission (by decreasing viral load)
3+ ARTs best to suppress replication and limit resistance
Combination ARTs reduces viral loads by 90-99% WHEN USED PROPERLY
Expense (not covered), side effects and strict schedules decrease adherence
NRTIs/NtRTIs Always used in combination ART
Blocks developing HIV DNA chain by inserting a protein, leaving HIV DNA incomplete. RNA
phase unaffected
S/E:
- lipodystrophy... redistribution of lipids from face and extremities to trunk and back
- Lactic acidosis with hepatic involvement
NNRTIs Can be used in combination ART
Stops viral replication from RNA to DNA
S/E:
,- rash
- hypersensitivity
- increased LFTs
- pancreatitis
Protease Inhibitor Can be used in combination ART
Prevents protease enzyme from cutting HIV into lengths required to assemble in cell
S/E:
- dysglycemia
- lipodystrophy
- hyperlipidemia
Integrase Inhibitor Can be used in combination ART
Prevents viral DNA integration into CD4+ T cell chromosomes
S/E:
- diarrhea
- nausea
- fatigue
- headache
- insomnia
Fusion Inhibitors Can be used in combination ART
, Prevents binding of HIV into healthy cells
S/E:
- diarrhea
- N/V
- fatigue
HIV: Metabolic Disorders Lipodystrophy: fat deposits into abdomen, upper back, breasts...
fat loss in arms, legs and face
Dyslipidemia (incr TG, decr HDLs)
Insulin resistance
Bone disease
Causes: HIV infection, ART, genetics, chronic stress creates pseudodiabetic state (cortisol
release incr BG + TG).
HIV: Nursing Care Planned based on stage of infection, risk of/actual infx, social factors
Assessment includes: risk behaviour, knowledge, skills
Nutritional support (vitamins and macronutrients)
VERIFIED
HIV: Pharmacological Treatment Goals:
Decrease viral load and retain CD4+ T cells
Delay symptoms and opportunistic infections
Prevent transmission (by decreasing viral load)
3+ ARTs best to suppress replication and limit resistance
Combination ARTs reduces viral loads by 90-99% WHEN USED PROPERLY
Expense (not covered), side effects and strict schedules decrease adherence
NRTIs/NtRTIs Always used in combination ART
Blocks developing HIV DNA chain by inserting a protein, leaving HIV DNA incomplete. RNA
phase unaffected
S/E:
- lipodystrophy... redistribution of lipids from face and extremities to trunk and back
- Lactic acidosis with hepatic involvement
NNRTIs Can be used in combination ART
Stops viral replication from RNA to DNA
S/E:
,- rash
- hypersensitivity
- increased LFTs
- pancreatitis
Protease Inhibitor Can be used in combination ART
Prevents protease enzyme from cutting HIV into lengths required to assemble in cell
S/E:
- dysglycemia
- lipodystrophy
- hyperlipidemia
Integrase Inhibitor Can be used in combination ART
Prevents viral DNA integration into CD4+ T cell chromosomes
S/E:
- diarrhea
- nausea
- fatigue
- headache
- insomnia
Fusion Inhibitors Can be used in combination ART
, Prevents binding of HIV into healthy cells
S/E:
- diarrhea
- N/V
- fatigue
HIV: Metabolic Disorders Lipodystrophy: fat deposits into abdomen, upper back, breasts...
fat loss in arms, legs and face
Dyslipidemia (incr TG, decr HDLs)
Insulin resistance
Bone disease
Causes: HIV infection, ART, genetics, chronic stress creates pseudodiabetic state (cortisol
release incr BG + TG).
HIV: Nursing Care Planned based on stage of infection, risk of/actual infx, social factors
Assessment includes: risk behaviour, knowledge, skills
Nutritional support (vitamins and macronutrients)
