Exam 2: MH701 / MH 701 (Latest
Update )
Psychopharmacologic / Neuroscience
Foundations of Mental Health Care
| Test Review Questions and
Answers | 100% Correct - Frontier
Question:
Valproic acid (Depakote) is FDA approved for ______________
Answer:
acute mania and mixed episodes
Question:
Valproic acid (Depakote) is used off-label for _____________
Answer:
*Maintenance treatment of bipolar disorder
*Bipolar depression
*Psychosis, Schizophrenia (adjunctive) *Dementia with behavioral
disturbances
,Question:
Valproic Acid (Depakote) pharmacologic actions
Answer:
misunderstood
GABA activity possibly
sodium channels
extrahypothalamic neuropeptides
absorbed 1-2 hours
peak concentrations 4-5 hours
highly protein bound
plasma life is 10-16 hours
ER option produces lower peak concentrations and higher minimum
concentrations and can be given 1x/day
Question:
When treating people with valproic acid (Depakote) for acute mania, about
2/3 of people respond within ________ days of achieving serum
concentrations of ___________ mmol/L
Answer:
1-4, 50
,Question:
gradual dosing of valproic acid (Depakote) may achieve serum concentrations
within _________week(s); rapid loading achieve serum concentrations within
__________ day(s) and control symptoms within __________day(s)
Answer:
1, 1, 5
Question:
When used for acute mania, Valproic Acid (Depakote) can be augmented
with ____________ or ____________
Answer:
carbamazepine (Tegretol)
antipsychotics
Question:
When used for acute bipolar depression, valproic acid (Depakote) is more
effective in treating __________ than ___________
Answer:
agitation, dysphoria
, Question:
When used for schizoeffective/schizophrenia ___________________ may
accelerate the response to antipsychotic therapy but is ineffective if used
alone for psychotic symptoms
Answer:
valproic acid (Depakote)
Question:
These are other off-label uses for valproic acid (Depakote)
Answer:
• Alcohol withdrawal and relapse prevention
• Panic disorder
• PTSD
• Impulse control
• Personality disorders
• Behavioral agitation
• Dementia
Update )
Psychopharmacologic / Neuroscience
Foundations of Mental Health Care
| Test Review Questions and
Answers | 100% Correct - Frontier
Question:
Valproic acid (Depakote) is FDA approved for ______________
Answer:
acute mania and mixed episodes
Question:
Valproic acid (Depakote) is used off-label for _____________
Answer:
*Maintenance treatment of bipolar disorder
*Bipolar depression
*Psychosis, Schizophrenia (adjunctive) *Dementia with behavioral
disturbances
,Question:
Valproic Acid (Depakote) pharmacologic actions
Answer:
misunderstood
GABA activity possibly
sodium channels
extrahypothalamic neuropeptides
absorbed 1-2 hours
peak concentrations 4-5 hours
highly protein bound
plasma life is 10-16 hours
ER option produces lower peak concentrations and higher minimum
concentrations and can be given 1x/day
Question:
When treating people with valproic acid (Depakote) for acute mania, about
2/3 of people respond within ________ days of achieving serum
concentrations of ___________ mmol/L
Answer:
1-4, 50
,Question:
gradual dosing of valproic acid (Depakote) may achieve serum concentrations
within _________week(s); rapid loading achieve serum concentrations within
__________ day(s) and control symptoms within __________day(s)
Answer:
1, 1, 5
Question:
When used for acute mania, Valproic Acid (Depakote) can be augmented
with ____________ or ____________
Answer:
carbamazepine (Tegretol)
antipsychotics
Question:
When used for acute bipolar depression, valproic acid (Depakote) is more
effective in treating __________ than ___________
Answer:
agitation, dysphoria
, Question:
When used for schizoeffective/schizophrenia ___________________ may
accelerate the response to antipsychotic therapy but is ineffective if used
alone for psychotic symptoms
Answer:
valproic acid (Depakote)
Question:
These are other off-label uses for valproic acid (Depakote)
Answer:
• Alcohol withdrawal and relapse prevention
• Panic disorder
• PTSD
• Impulse control
• Personality disorders
• Behavioral agitation
• Dementia
