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MIC205A Exam 4 2025/2026 Exam Questions with 100% Correct Answers | Latest Update

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MIC205A Exam 4 2025/2026 Exam Questions with 100% Correct Answers | Latest Update Dancing with Microbes -

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MIC205A Exam 4 2025/2026 Exam
Questions with 100% Correct Answers |
Latest Update



Dancing with Microbes - 🧠 ANSWER ✔✔-Microbes are ubiquitous


-Microbes are breathed in, ingested, and picked up on skin

-Most do not harm us, many are beneficial

-Some colonize on skin and mucous membrane, most ingested microbes

die in stomach or excreted

-Some shed with dead epithelial cells

-Relatively few microbes evade defense and cause diseases -> distinct

characteristics allow avoidance of some body defenses


Normal microbiota - 🧠 ANSWER ✔✔-Not harmful


-Organisms that routinely reside on body's surfaces

-Relationship is delicate balance; some can cause disease if there is an

opportunity (weakness or defects n innate or adaptive defenses can leave



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,individuals vulnerable to invasion -> malnutrition, cancer, AIDS or other

disease, surgery, wounds, genetic defects, alcohol or drug abuse, and

immunosuppressive therapy)

-Permanently colonize the host


Symbiosis - 🧠 ANSWER ✔✔-Different organisms living together


-Mutualism - 🧠 ANSWER ✔✔-Kind of symbiosis


-Both partners benefit

-Example: in large intestine, some bacteria synthesize vitamin K and B

vitamins, which host can absorb; bacteria are supplied with warmth, energy

sources


Commensalism - 🧠 ANSWER ✔✔-Kind of symbiosis


-One partner benefits without harming the other partner

-Many microbes living on skin neither harmful nor helpful, but obtain food

and necessities from host


Parasitism - 🧠 ANSWER ✔✔-Type of symbiosis


-One organism benefits at expense of other




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,-All pathogens are parasites, but medical microbiologists often reserve for

eukaryotic pathogens (for example, protozoa, helminths)


Opportunistic pathogens - 🧠 ANSWER ✔✔-Take advantage of weakened

immune system


Microbiota/Microbiome - 🧠 ANSWER ✔✔-A collection of microbes in a

given ecological niche

-Important to human health

-Relatively little is known

-Human Microbiome Project studying microbiota using metagenomics,

analysis of DNA without culturing


Transient microbiota - 🧠 ANSWER ✔✔-May be present for days, weeks, or

months

-Inhabit temporarily


Composition of the Normal Microbiota - 🧠 ANSWER ✔✔-37 trillion human

cells

-100 trillion bacteria, 70-80% non-culturable




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, -Estimated bacterial species: 5,000-35,000 in intestine, 300-500 in mouth,

120 species on skin

-160-fold more gene in gut microbiome than in human genome

-We get our microbiomes at birth, during breast feeding, and from food and

the environment

-Obese people have more Firmicutes while lean people have more

Bacteroides

-Weight loss changes microbiota to resemble that of lean people

-Composition different among individuals and over time

-Changes with physiological state and life style of host


Normal Microbiota and Your Health - 🧠 ANSWER ✔✔-Microbial antagonism

or competitive exclusion: occupying sites of attachment; nutrient

competition; antibiotic compounds (bacteriocins); alter environment (lower

pH)

-Training adaptive immune system (hygiene hypothesis): activate B and T

cells; develop tolerance to routine microbes in guts, food, and on other

mucosal membranes -> insufficient exposure to microbes leads to allergies;




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