Introduction to Genetic Analysis
Anthony J.F. Griffiths, John Doebley, Catherine Peichel, and David A. Wassarman
12th Edition
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,TablehlofhlContents
Chapterhl01hlThehlGeneticshlRevolution 1
Chapterhl02hlSinglehlGenehlInheritance 6
Chapterhl03hlIndependenthlAssortmenthlofhlGenes 26
Chapterhl04hlMappinghlEukaryotehlChromosomeshlbyhlRecombination 43
Chapterhl05hlGenehlInteraction 63
Chapterhl06hlThehlGeneticshlofhlBacteriahlandhlTheirhlViruses 84
Chapterhl07hlDNAhlStructurehlandhlReplication 104
Chapterhl08hlRNAhlTranscriptionhlProcessinghlandhlDecay 117
Chapterhl09hlProteinshlandhlTheirhlSynthesis 130
Chapterhl10hlGenehlIsolationhlandhlManipulation 141
Chapterhl11hlRegulationhlofhlGenehlExpressionhlinhlBacteriahlandhlTheirhlViruses 160
Chapterhl12hlRegulationhlofhlGenehlExpressionhlinhlEukaryotes 175
Chapterhl13hlThehlGenetichlControlhlofhlDevelopment 184
Chapterhl14hlGenomeshlandhlGenomics 192
Chapterhl15hlDNAhlDamagehlRepairhlandhlRecombination 197
Chapterhl16hlThehlDynamichlGenomehlTransposablehlElements 216
Chapterhl17hlLargehlScalehlChromosomalhlChanges 225
Chapterhl18hlPopulationhlGenetics 243
Chapterhl19hlThehlInheritancehlofhlComplexhlTraits 258
Chapterhl20hlEvolutionhlofhlGeneshlandhlTraits 270
PlusBay.Plus
, TesthlBankhl-hlIntroductionhltohlGenetichlAnalysis,hl12thhlEditionhl(Griffiths,hl2021)
Chapterhl01:hlThehlGeneticshlRevolution
1. Thehlearlyhl1900shlwashlanhlimportanthlperiodhlforhlgeneticshlduehltohlwhichhlofhlthehlfollowinghlmajorhlevents?
a. thehlrediscoveryhlofhlGregorhlMendel'shlscientifichlfindings
b. WatsonhlandhlCrickhlsolvinghlthehlstructurehlofhlDNA
c. WalterhlSuttonhlandhlTheodorehlBoverihlhypothesizinghlthathlchromosomeshlarehlthehlhereditaryhlelements
d. thehlrediscoveryhlofhlGregorhlMendel'shlscientifichlfindingshlandhlWalterhlSuttonhlandhlTheodoreh
lBoverihlhypothesizinghlthathlchromosomeshlarehlthehlhereditaryhlelements
e. Allhlofhlthehlanswerhloptionshlarehlcorrect.
ANSWER:h l e
2. Ahlsamplehlofhlnormalhldouble-
strandedhlDNAhlwashlfoundhltohlhavehlahlguaninehlcontenthlofhl18%.hlWhathlishlthehlexpectedhlproportionhlofhladeni
ne?
a. 9%
b. 32%
c. 36%
d. 68%
e. 82%
ANSWER:h l b
3. InhlonehlstrandhlofhlDNA,hlthehlnucleotidehlsequencehlishl5'-ATGC-
3'.hlThehlcomplementaryhlsequencehlinhlthehlotherhlstrandhlmusthlbe
a. 3'-ATGC-5'.
b. 3'-TACG-5'.
c. 5'-ATCG-3'.
d. 5'-CGTA-3'.
e. 5'-TACG-3'.
ANSWER:h l b
4. HowhlmanyhldifferenthlDNAhlmoleculeshlthathlarehleight-nucleotide-pairshllonghlarehltheoreticallyhlpossible?
a. 24
b. 32
c. 64
d. 256
e. 65,536
ANSWER:h l e
5. Whichhlofhlthehlfollowinghlis/arehlTRUEhlabouthlgenes?
a. Geneshlarehllocatedhlonhlchromosomes.
b. Geneshlcomehlinhlvariantshlknownhlashlalleles.
c. Geneshlusuallyhlencodehlproteinhlproducts.
d. Allhlofhlthehlanswerhloptionshlarehlcorrect.
e. Nonehlofhlthehlanswerhloptionshlishlcorrect.
ANSWER:h l d
1 |hlPhlahlghle
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, TesthlBankhl-hlIntroductionhltohlGenetichlAnalysis,hl12thhlEditionhl(Griffiths,hl2021)
6. Wildhlcatshl(Felishlsilvestris)hlandhlcommonhlmicehl(Mushlmusculus)hlarehldiploid.hlInhlwildhlcats,hl2nhl=hl3
8,hlwhilehlinhlcommonhlmice,hl2nhl=hl40.hlBasedhlonhlthishlinformation,hlwehlcanhlconcludehlthathlwild-
cathlcellshlhave
a. lesshlDNAhlthanhlcommon-mousehlcells.
b. smallerhlgenomeshlthanhlcommon-mousehlcells.
c. fewerhlDNAhlmoleculeshlthanhlcommon-mousehlcells.
d. fewerhlgeneshlthanhlcommon-mousehlcells.
e. fewerhlsetshlofhlchromosomeshlthanhlcommon-mousehlcells.
ANSWER:h l c
7. WhichhlofhlthehlfollowinghlishlahlcomponenthlofhlDNA?
a. alanine
b. arginine
c. cysteine
d. guanine
e. tyrosine
ANSWER:h l d
8. Whichhlofhlthehlfollowinghlis/arehlTRUEhlofhlthehlDNAhlstructurehlsolvedhlbyhlWatsonhlandhlCrick?
a. Ithlishlahldouble-helicalhlstructure.
b. Sugar–phosphatehlbackbonehlishlalwayshltowardhlthehloutsidehlofhlthehlDNA.
c. TherehlarehltwohlhydrogenhlbondshlbetweenhlAhlandhlThlandhlthreehlhydrogenhlbondshlbetweenhlChlandhlG.
d. Therehlarehlfourhltypeshlofhlnitrogenoushlbases.
e. Allhlofhlthehlanswerhloptionshlarehlcorrect.
ANSWER:h l e
9. WhichhlofhlthehlfollowinghlishlahlCORRECThlrepresentationhlofhlthehlcentralhldogma?
a. RNAhl→hlDNAhl→hlprotein
b. proteinhl→hlDNAhl→hlRNA
c. DNAhl→hlRNAhl→hlprotein
d. DNAhl→hlproteinhl→hlDNA
e. Nonehlofhlthehlanswerhloptionshlishlcorrect.
ANSWER:h l c
10. Youhlhavehlcomehlacrosshlahldoghl(namedhlCindy)hlthathldoeshlnothlhavehlahltail.hlInterestingly,hlallhlthehlpuppie
shlproducedhlbyhlthishldoghldon'thlhavehlahltail.hlIfhlthehllackhlofhltailhlishlcausedhlbyhlahlgenetichlmutation,hlwherehl
hashlthishlmutationhlmosthllikelyhltakenhlplace?
a. inhlCindy'shlgametes
b. inhlthehlcellshlthathlshouldhlnormallyhlhavehlgivenhlrisehltohlCindy'shltail
c. inhlthehlcellshlthathlshouldhlnormallyhlhavehlgivenhlrisehltohlCindy'shlandhlherhlpuppies'hltails
d. inhlallhlofhlCindy'shlcellshl(includinghlherhlgametes)
e. inhlahlgametehlofhlonehlofhlCindy'shlparents
ANSWER:h l a
11. Whichhlofhlthehlfollowinghlfeatureshlmakeshlahlspecieshlsuitablehlashlahlmodelhlorganism?
2 |hlPhlahlghle
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