Test Bank For Psychopharmacology: Drugs, the Brain and Behavior 4th Edition By Meyer,ISBN;9781605359878 All Chapters Covered,Complete Guide A+.

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, Chapter 1: Principles of Pharmacology
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Multiple Choice

1. refer(s) to specific molecular changes that occur when a drug binds to a
particular target site or receptor, while are the resulting widespread alterations
in function.
a. Drug action; therapeutic effects
b. Side effects; drug effects
c. Therapeutic effects; side effects
d. Drug action; drug effects
Answer: d
Textbook Reference: Pharmacology: The Science of Drug Action

2. After drug administration has occurred, the amount of drug in the blood that is free to
bind at specific target sites is referred to as
a. the therapeutic dose.
b. first-pass effects.
c. bioavailability.
d. ED50.
Answer: c
Textbook Reference: Pharmacokinetic Factors Determining Drug Action

3. The specific molecular changes that occur when a drug binds to a particular target site
or receptor are referred to as
a. drug effects.
b. drug action.
c. side effects.
d. placebo effects.
Answer: b
Textbook Reference: Pharmacology: The Science of Drug Action

4. Which of the following is not a possible explanation for placebo effects?
a. Pavlovian conditioning
b. Genetic variation
c. Drug competition
d. Expectation of outcome
Answer: c
Textbook Reference: Pharmacology: The Science of Drug Action




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,5. The administration $rof $roxytocin $rhas $rbeen $rproposed $ras $ra $rtreatment $rfor $rautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: $rc
Textbook $rReference: $rPharmacokinetic $rFactors $rDetermining $rDrug $rAction

6. Which $rfactor $rdoes $rnot $raffect $rthe $rpharmacokinetics $rof $ra $rdrug?
a. Route $rof $radministration
b. Lipid $rsolubility
c. Depot $rbinding
d. Drug $raction
Answer: $rd
Textbook $rReference: $rPharmacokinetic $rFactors $rDetermining $rDrug $rAction

7. First-pass $rmetabolism $roccurs $rwhen $rdrugs $rare $rtaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: $ra
Textbook $rReference: $rPharmacokinetic $rFactors $rDetermining $rDrug $rAction

8. The $rarea $rpostrema $ris $rone $rarea $rin $rthe $rbrain $rwhere $rthe is $rnot $rcomplete.
a. cerebrospinal $rfluid
b. blood–brain $rbarrier
c. choroid $rplexus
d. phospholipid $rmembrane
Answer: $rb
Textbook $rReference: $rPharmacokinetic $rFactors $rDetermining $rDrug $rAction

9. First-pass $rmetabolism $roccurs $rwith $rorally $radministered $rdrugs $rbecause
a. their $rabsorption $ris $rslowed $rby $rfood.
b. drugs $rabsorbed $rinto $rthe $rbloodstream $rfrom $rthe $rstomach $rgo $rto $rthe $rliver $ron $rthe
$rway $rto $rgeneral $rcirculation.

c. drugs $rmust $rfirst $rsurvive $rthe $racidic $renvironment $rof $rthe $rstomach.
d. salivary $renzymes $rin $rthe $rmouth $rbegin $rthe $rprocess $rof $rmetabolism.
Answer: $rb
Textbook $rReference: $rPharmacokinetic $rFactors $rDetermining $rDrug $rAction

10. Toxic $rsubstances $rin $rthe $rblood $rtrigger $ra $rvomiting $rresponse $rby $ractivating $rthe
a. blood–brain $rbarrier.
b. choroid $rplexus.
c. area $rpostrema.
d. median $reminence.



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, Answer: $rc
Textbook $rReference: $rPharmacokinetic $rFactors $rDetermining $rDrug $rAction

11. Drugs $radministered $r_ have $rthe $rmost $rrapid $ronset $rof $raction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: $rd
Textbook $rReference: $rPharmacokinetic $rFactors $rDetermining $rDrug $rAction

12. Ionization $rof $ra $rdrug $rdepends $ron $rthe of $rthe $rsolution $rand $rthe of
$rthe $rdrug.

a. pH; $rpKa
b. pKa; $rpH
c. concentration; $rlipid $rsolubility
d. pH; $rconcentration
Answer: $ra
Textbook $rReference: $rPharmacokinetic $rFactors $rDetermining $rDrug $rAction

13. The $rabsorption $rof $ra $rdrug $rdepends $ron $rall $rof $rthe $rfollowing $rexcept
a. lipid $rsolubility.
b. ionization.
c. body $rtemperature.
d. the $rconcentration $rof $rthe $rdrug.
Answer: $rc
Textbook $rReference: $rPharmacokinetic $rFactors $rDetermining $rDrug $rAction

14. Drugs $rthat $rare should $rbe $ravoided $rby $rwomen $rof $rchildbearing $rage.
a. teratogenic
b. able $rto $rcross $rthe $rplacental $rbarrier
c. psychoactive
d. highly $rlipid-soluble
Answer: $ra
Textbook $rReference: $rPharmacokinetic $rFactors $rDetermining $rDrug $rAction

15. Agents $rthat $rinduce $rdevelopmental $rabnormalities $rin $ra $rfetus $rare $rknown $ras
a. psychoactive $rdrugs.
b. illicit $rdrugs.
c. teratogens.
d. placental $rdrugs.
Answer: $rc
Textbook $rReference: $rPharmacokinetic $rFactors $rDetermining $rDrug $rAction

16. Depot $rbinding $ris $rsaid $rto $roccur $rwhen $rdrugs
a. bind $rto $rtheir $rtarget $rsites.



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