Mccance pathophysiology the biologic basis for disease in adults and children 8th edition kathryn l mccance test bank

TESTBANK
PATHOPHYSIOLOGY
TheBiologic Basis ForDiseaseInAdults
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And Children
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8THEDITIONBYKATHRYNL.
MCCANCE

,McCance:Pathophysiology:TheBiologicBasisforDiseaseinAdultsandChildren(8thEdition)TESTBANK
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CONTENTS:
Chapter i#01:Cellular i#Biology
Chapteri#02:AlteredtCellularandTissuei#Biology:Environmentali#Agents
Chapteri#03:The i#Cellulari#Environment: i#Fluidsand i#Electrolytes, i#Acidstand i#Bases
Chapteri#04:Genesandi#Genetici#Diseases
Chapter05:Genes,Environment-Lifestyle,andtCommontDiseases
Chapteri#06:EpigeneticsandtDisease
Chapter07:InnatetImmunity: i# Inflammationand i# WoundtHealing
Chapter i#08:Adaptive i#Immunity
Chapteri#09:AlterationsinImmunityandtInflammation
Chapteri#10:Infection
Chapter i#11:Stresstand i#Disease
Chapter i#12:Cancer i#Biology
Chapter i#13:Cancer i#Epidemiology
Chapteri#14:i#Canceri#ini#Children
Chapter i#15:Structuretand i#FunctiontofthetNeurologictSystem
Chapter i#16:Pain, i#Temperature i#Regulation, i#Sleep,and i#SensoryFunction
Chapter i#17:AlterationsintCognitivetSystems, i#CerebraltHemodynamics,andMotorFunction
Chapter i#18:Disorderstofthe i# CentralandtPeripheral i#NervousSystemstandthe i#Neuromuscular i#Junction
Chapteri#19:NeurobiologyofSchizophrenia,i#MoodtDisorders,andtAnxietyDisorders
Chapteri#20:AlterationsofNeurologici#FunctiontinChildren
Chapteri#21:MechanismsofHormonal i#Regulation
Chapteri#22:AlterationsofHormonal i#Regulation
Chapteri#23:Obesityandi#DisordersofNutrition
Chapter i#24:Structuretand i#FunctiontofthetReproductive i#Systems
Chapteri#25:Alterationsofthei#FemaletReproductivei#System
Chapteri#26:Alterationsofthe i#MaleReproductivetSystem
Chapteri#27:SexuallyTransmittedi#Infections
Chapteri#28:StructuretandtFunctionofthei#HematologictSystem
Chapter i#29:AlterationsofErythrocytes, i#Platelets, i#and i#Hemostatic i#Function
Chapteri#30:AlterationsofLeukocyteandtLymphoid i#Function
Chapteri#31:AlterationsofHematologici#Functiontini#Children
Chapter i#32:StructuretandtFunctionofthe i#Cardiovascularand i#Lymphatic i#Systems
Chapteri#33:AlterationsofCardiovasculari#Function
Chapteri#34:AlterationsofCardiovascular i#FunctionintChildren
Chapter i#35:Structuretand i#FunctiontofthetPulmonarySystem
Chapteri#36:AlterationsofPulmonaryFunction
Chapteri#37:i#AlterationsofPulmonaryFunctiontini#Children
Chapter i#38:Structuretand i#FunctiontofthetRenaltand i#UrologictSystems
Chapteri#39:i#AlterationsofRenalandi#UrinaryTracti#Function
Chapter i#40: i#AlterationsofRenaltand i#UrinaryTract i#Functiontin i#Children
Chapter i#41:Structuretand i#FunctiontofthetDigestivetSystem
Chapteri#42:AlterationsofDigestive i#Function
Chapter i#43:AlterationsofDigestivetFunctionin i#Children
Chapteri#44:StructuretandtFunctionofthei#MusculoskeletaltSystem
Chapteri#45:AlterationsofMusculoskeletali#Function
Chapteri#46:AlterationsofMusculoskeletali#FunctionintChildren
Chapteri#47:Structure,i#Function,i#andi#Disordersofthei#Integument
Chapteri#48:i#Alterationsofthei#IntegumentintChildren
Chapter i#49:Shock, i#MultipletOrgantDysfunctiontSyndrome, i#andtBurnsintAdults
Chapteri#50:Shock,MultipletOrgantDysfunctiontSyndrome,andtBurnsintChildren

, McCance:Pathophysiology:TheBiologicBasisforDiseaseinAdultsandChildren(8thEdition)TESTBANK
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Part 1:i#CENTRALCONCEPTSOFPATHOPHYSIOLOGY:CELLSANDTISSUES i#Uniti#I:
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i#THECELL




CHAPTER 01:i#CELLULARBIOLOGY
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MULTIPLECHOICE

1. Whichstatementbestdescribesthe cellularfunction ofmetabolicabsorption?
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a. Cellscanproduceproteins.
b. Cellscansecretei#digestive enzymes. t


c. Cellsi#cani#takeinanduse nutrients. t


d. Cellscansynthesizefats.

ANS: i#C
Ini#metabolicabsorption,i#allcellstake inand use nutrients andothersubstancesfrom theirsurrounding
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i#s.Theremaining options arenotinclusivein theirdescriptions ofcellularmetabolicabsorption.
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PTS: i # 1 DIF: CognitiveLevel:Remembering

2. Whereis mostofa cell’s i#geneticinformation, i#includingRNAand i#DNA, i#contained?
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a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome

ANS: i#C
The nucleuscontainsthenucleolus, asmalldensestructurecomposed largelyofRNA,mostofthe cell
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i # i # ularDNA,i#andthei#DNA-

binding proteins,i#suchi#as thei#histones,i#whichregulateits activity.i#Themitochondriaareresponsiblei#fo
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i#rcellularrespiration andenergyproduction.
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Ribosomes’chieffunctionistoprovidesites forcellularproteinsynthesis.i#Lysosomesfunction asi#thei
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i#ntracellulardigestivesystem.




PTS: i # 1 DIF: CognitiveLevel:Remembering

3. Whichcomponentofthecellproduceshydrogenperoxide(H2O2) byusing oxygentoi#removehydr t t


ogenatomsfromspecificsubstratesini#ani#oxidativereaction?
i#

a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome

ANS: i#B

, McCance:Pathophysiology:TheBiologicBasisforDiseaseinAdultsandChildren(8thEdition)TESTBANK t t t




Peroxisomesaresonamedbecausetheyusuallycontainenzymesthatuseoxygen toremovehydroge t


i#natoms fromspecificsubstratesin anoxidative reactionthatproducesH2O2,whichisapowerful i#oxid
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i#ant andpotentiallydestructiveif it accumulatesorescapesfromperoxisomes.
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RibosomesareRNA-
proteincomplexes(nucleoproteins) i#thataresynthesizedin thenucleolusandsecretedintothe cytopla t t


i#smthroughporesinthe nuclearenvelopecalled t i#nuclearporecomplexes.

i#Lysosomesaresaclikestruc i#turesthatoriginatefromtheGolgicomplexand containmorethan40 t


i#digestiveenzymescalled hydrol i#ases, whichcatalyze bonds inproteins, lipids,
t i#nucleicacids, t t t t


i#and carbohydrates. i#An i#endosomeis aves i#icalthat hasbeenpinchedofffromthe cellularmembrane.
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PTS: i # 1 DIF: i # i # CognitiveLevel:Remembering

4. Whichcellcomponentiscapableofcellularautodigestionwhen itisreleasedduringcellinjury? t


a. Ribosome
b. Golgicomplex
c. Smoothendoplasmic reticulum t


d. Lysosomes

ANS: i#D
The lysosomalmembraneacts i#as i#aprotectiveshieldbetweenthepowerfuldigestiveenzymeswithint
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i#helysosome andthecytoplasm, t i#preventingtheirleakage intothecytoplasmicmatrix. t


i#Disruption ofth t


i#emembranebyvarious treatments orcellularinjuryleadstoarelease ofthelysosomalenzymes,
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i # whic i # hi#can then reacti#withtheirspecificsubstrates, i#causingi#cellularself-
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digestion.The chieffunctionofa ribosome is toprovidesitesforcellularprotein synthesis.
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i#Golgi i#complexisanetworkofflattened,

i#smoothvesicles andmembranesoftenlocatednearthe cellnucleus.
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i#The smoothendoplasmic reticulum is involved insteroidhormoneproduction andremovingtoxicsu
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i#bstances fromthecell. t




PTS: i # 1 DIF: i # i # CognitiveLevel:Remembering

5. WhichcAMP-mediatedresponseisrelated toantidiuretic hormone? t t


a. Increased heart rate andforce ofcontraction
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b. Secretionofcortisol
c. Increased retentionofwater t


d. Breakdownof fat t




ANS: i#C
Antidiuretichormone leads toincreasedretentionofwaterinthebody. i#Epinephrinecauses increases i
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i#nheartrateandforceofcontraction. i#Increasedcortisolsecretion isduetoACTH. i#Breakdownoffatisd t


i#ueto glucagon.t




PTS: i # 1 DIF: i # i # CognitiveLevel:Remembering

6. Duringwhichphaseofthecellcycleisi#DNAsynthesized?
a. G1
b. S
c. G2
d. M