mcb4271 amr final

mcb4271 amr final
Study online at https://quizlet.com/_chvuhs

1. mechanism of ac- - mimics the dipeptide D-Alanyl-D-Alanine
tion and struc- - interrupts bacterial cell wall formation
ture: beta-lac- - binds to penicillin-binding proteins (PBP)
tams - house with a garage




2. types of beta lac- - penicillins
tams - cephalosporins
- carbapenems
- monobactams
- clavams

3. types of penicillin - penicillin g
- penicillin v
- methicillin
- ampicillin
- amoxicillin

4. mechanism of ac- - inhibits cell wall synthesis by blocking peptidoglycan polymerization
tion and struc- - vancomycin: caps D-Ala-D-Ala
ture: glycopep- - sugar molecule with amino acids and carboxyl groups
tides




5. mechanism of ac- - inhibits D-Ala-D-Ala synthesis
tion and struc-
ture: cycloserine



, mcb4271 amr final
Study online at https://quizlet.com/_chvuhs




6. mechanism of ac- - inhibits flippase; cannot flip back to the membrane to pick up new lipid
tion and struc- - ex. bacitracin
ture: lipopeptides - cyclical arrangement with a peptide side chain




7. mechanism of - targets folic acid synthesis (dihydropteroate synthase)
action: sulfon- - almost always given with trimethoprim (targets dihydrofolate reductase)
amides

8. mechanism of ac- - targets type II topoisomerase (gyrase and topo IV); basically inhibits DNA repli-
tion and struc- cation
ture: quinolones - ex. fluoroquinolone
- look for the fluoro




9. mechanism of ac- - binds to 30S subunit and inhibits protein synthesis
tion and struc- - can be given with beta-lactams to be stronger
ture: aminoglyco- - amino group with a glycoside (R-O-R); three cyclic rings
sides