MDSC 515 FINAL EXAM STUDY GUIDE LATEST UPDATE ALL WITH 580 QUESTIONS AND CORRECT SOLUTIONS JUST RELEASED THIS YEAR

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MDSC 515 FINAL EXAM STUDY GUIDE LATEST
UPDATE ALL WITH 580 QUESTIONS AND
CORRECT SOLUTIONS JUST RELEASED THIS
YEAR
Question: fibrinous inflammation - CORRECT ANSWER✔✔-pericarditis

-stiffening of the pericardial sac

-heart failure - back flow of blood




Question: antigens - CORRECT ANSWER✔✔-molecules originating from foreign entities
(pathogens, foreign organisms or tissues) that provoke a specific immune response

-most are proteins or large polysaccharides

-microbes: capsules, cell walls, toxins, flagella, viral capsids

-non-microbes: pollen, red blood cell surface molecules, and surface molecules from
transplanted tissues




Question: epitope - CORRECT ANSWER✔✔-physical part of an antigen that interacts with an
antibody/T cell receptor

-any given antigen may have several epitopes and not every epitope is the same for all antigens




Question: antibodies - CORRECT ANSWER✔✔-proteins made by B lymphocytes

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-recognize and bind to a particular antigen with high specificity




Question: suppurative inflammation - CORRECT ANSWER✔✔-pus or abscess

-abscess contains neutrophils and cellular debris and is surrounded by congested blood vessels -
deep and cannot be cleared




Question: chronic duodenal ulcer - CORRECT ANSWER✔✔-crater with acute inflammatory
exudate (fluid) at the base - hole where there is normally epithelial tissue




Question: outcomes of acute inflammation - CORRECT ANSWER✔✔-complete resolution (ideal)

-healing/fibrosis (scarring or build up of tissue where a severe injury was)

-chronic inflammation (could not remove the inflammatory stimulus and there is now a systemic
effect on the metabolic system




Question: excessive inflammation - CORRECT ANSWER✔✔-extreme reaction to acute stimulus

-allergies

-autoimmune diseases

-atherosclerosis -plaques alone blood vessels of the heart

-alzheimer disease

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Question: leukocyte-induced chronic inflammation - CORRECT ANSWER✔✔-athritis

-atherosclerosis

-chronic transplat rejection

-pulmonary fibrosis




Question: defects in leukocyte function - CORRECT ANSWER✔✔inherited (parental or
congenital defects):

-leukocyte adhesion

-phagolysosome function (reduced pH in environment to make it acidic to kill microbes)

-microbicidal activity (lethal environment for microbes)

Acquired:

-bone marrow suppression - abnormal WBC production - inability to fight inflammation and
infection

defective inflammation:

-increased susceptibility to infection

-delayed wound healing




Question: chronic inflammation - CORRECT ANSWER✔✔-inflammation of prolonged duration in
which inflammation, tissue injury and attempts to repair coexist, in trying combinations

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Question: chronic inflammation causes - CORRECT ANSWER✔✔-persistent infection

-immune-mediated inflammatory disease (self, x-reactive (when the body accidentally attacks
its own tissues, common environmental substances)

-prolonged exposure to toxic agents (silica (cell damage in the lungs and eventually fibrosis from
the build up of scar tissue, cholesterol (builds up on inflammatory cell walls unto plaque and
eventually fibrosis)




Question: chronic inflammation morphologic features - CORRECT ANSWER✔✔-infiltration with
mononuclear cells

-tissue destruction

-attempts at healing - fibrosis, angiogenesis (production of new blood vessels from old ones)




Question: innate immunity - CORRECT ANSWER✔✔-rapid and non-specific

-physical barriers: skin, mucosa

-phagocytic cells: neutrophils and monocytes/macrophages

-natural killer and dendritic cells

-plasma proteins and the complement system




Question: adaptive - CORRECT ANSWER✔✔-acquired with exposure