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Exam (elaborations)

PNB 2274 Exam1 2 3 and 4

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PNB 2274 Exam1 2 3 and 4 QUESTIONS AD CORRECT ANSWERS LATEST 2025

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PNB 2274 Exam1 2 3 and 4
Microvilli

✓ folding of the membrane that increase surface area for absorption



Function of Microvilli

✓ to increase surface area for absorption



Location of microvilli

✓ transport epithelia; kidney, intestine, some parts of the brain



Symporter

✓ secondary active transporter that allows two substances to travel in the same direction



Antiporter

✓ primary active pump that moves substances in opposite directions (ex. Na+ K+ pump)



Uniporter

✓ passive movement of one substance with concentration gradient



Epithelial Tissue Types

✓ secretory, protective, transport, ciliated, exchange



Secretory Epithelia

✓ cells are lined up in gland (as in sweat glands) and release sweat and other substances via
vesicles



Secretory Epithelia have a lot of (organelle types)

✓ golgi and endoplasmic reticulum (rough ER for protein, smooth ER for fat)

,Protective Epithelia

✓ have a lot of keratin and desmosomes that provide very strong, staple-like junctions



Function of Protective Epithelia

✓ to make sure our cells do not come apart with movement of the body



Type of junction in protective epithelia

✓ desmosomes



type of junction in transport epithelia

✓ tight junctions



4 Types of Junctions

✓ tight, adhering, desmosomes, gap junctions



Tight Junctions location

✓ more toward the apical surface of transporting epithelia



function of tight junctions

✓ prevent substances from moving between cells



structure of tight junctions

✓ ZO-1 binds with occludin (?)



Components of adhering junctions

✓ actin (intra) and cadherins (extracellular)



Location of adhering junctions

, ✓ deep to tight junctions, they encircle the cell immediately adjacent to all its neighbors



Location of desmosomes

✓ very common in epithelial cells



function of desmosomes

✓ hold together cells under a lot of stress



Button desmosomes function

✓ make sure the cells stay in place and do not pull off from one another and allow bending and
twisting



Mutation of proteins in hemidesmosomes can cause

✓ digestive issues (epithelial lining) as well as skin conditions



Structure of gap junctions

✓ provide a pore through the membrane to allow rapid communication between cells through
diffusion



How are gap junctions controlled

✓ transcription and translation



function of gap junctions

✓ homeostasis, cell growth and regeneration, embryonic development, electrical and metabolic
coupling



structure of a pore of a gap junction

✓ each pore has two hemichannels, each made up of 6 pore proteins



Exchange Epithelia

, ✓ have gaps but NOT gap junctions to allow for exchange of gases



location of exchange epithelia

✓ lungs, digestive system



Fact of Connective Tissues

✓ most abundant and widely distributed tissue type in the body



What can we call connective tissues

✓ the "glue" of the body



Structural components of connective tissues

✓ specialized cells, protein fibers, ground substance



extracellular matrix of connective tissue is made up of

✓ protein fibers and ground substance



specialized cell in bone

✓ osteocyte



specialized cell in cartilage

✓ chondrocyte



specialized cell in fat

✓ adipocyte



specific protein fibers in connective tissue

✓ elastic fibers, collagen, reticular fibers

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