set with Questions and correct/verified
Answers
Which statement is TRUE?
a. the sarcoplasmic reticulum is where actin and myosin are stored
b. a skeletal muscle cell is a very long, multi-nucleated cell
c. terminal cisternae are enlarged portions of the transverse tubules - ANSWER-b. a skeletal muscle cell is
a very long, multi-nucleated cell
When a sarcomere shortens, the protein(s) in the sarcomere that get(s) compressed is/are
a. Myosin
c. Titin
b. Nebulin
d. Titin and Nebulin - ANSWER-c. Titin
Which one of the following is FALSE?
a. Muscle cells membranes cannot produce APs
b. Membranes of skeletal muscle cells voltage-gated Na+ ion channels
c. Membranes at skeletal muscle cell motor endplates have ligand-gated Na+ ion channels - ANSWER-a.
Muscle cells membranes cannot produce APs
During cross-bridge cycling in STRIATED muscle cells, calcium ions must be fully bound
a. to actin
b. to myosin
c. to troponin
d. to tropomyosin - ANSWER-c. to troponin
Which correctly describes part of the "length-tension" relationship in SKELETAL muscle?
Note: length refers to current position or "length" immediately before the next contraction.
a. Maximal length results in optimal amount of overlap between thick & thin filaments
b. Maximal length results in maximal overlap between thick & thin filaments
c. Peak tension is generated at a medium amount of length
d. Peak tension is generated at maximum length - ANSWER-c. Peak tension is generated at a medium
amount of length
At the shortest possible sarcomere length...
a. each Z disk is as close as possible to myosin bundles and no more sliding can occur
b. there is optimal actin and myosin overlap for force production
c. there is little actin overlapping the nearby myosin, so force cannot be generated - ANSWER-a. each Z
disk is as close as possible to myosin bundles and no more sliding can occur
, Compared to when the cell is relaxed, when a Skeletal Muscle cell is generating force there is relatively
higher Ca2+ ion concentration in the
a. cytoplasm
b. sarcoplasmic reticulum
c. synaptic vesicles - ANSWER-a. cytoplasm
In a SKELETAL muscle cell, Ca2+ ion channels in the sarcoplasmic reticulum are
a. Voltage-gated
b. Ca2+ ion-gated
c. Mechano-gated - ANSWER-c. Mechano-gated
In a CARDIAC muscle cell, Ca2+ ion channels in the sarcoplasmic reticulum are
a. Voltage-gated
b. Ca2+ ion-gated
c. Mechano-gated - ANSWER-b. Ca2+ ion-gated
In SKELETAL muscles, cells that are specialized for very high ENDURANCE are called
a. Fast- glycolytic cells
b. Slow-oxidative cells
c. Slow-glycolytic cells - ANSWER-b. Slow-oxidative cells
SKELETAL muscle cells have
a. branched cells
b. gap junctions
c. uni-nucleated cells
d. transverse tubules
e. all of the above - ANSWER-d. transverse tubules
Which is the most correct statement? In skeletal muscle, the protein titin
a. runs the entire length of the actin filament
b. runs the entire length of the myosin filament
c. runs only from the end of myosin filament to the Z disk
d. runs from the end of actin filament to the M-line
e. runs along wrapping around the long wire-like nebulin protein - ANSWER-b. runs the entire length of
the myosin filament
Which is NOT a role for ATP in SKELETAL muscle cells?
a. energizing the CB head allowing it to bind and move the attached filament
b. modulating the CB head allowing it to unbind from the attached filament
c. used to gate RYR Ca2+ ion channels in the sarcoplasmic reticulum
d. used by Calcium-ion pumps to move Ca2+ into the sarcoplasmic reticulum
e. used by Na+/K+ ion pumps in the cell membrane - ANSWER-c. used to gate RYR Ca2+ ion channels in
the sarcoplasmic reticulum
Which is a FALSE statement about a CB cycle and the four steps of the cycle?