Final Exam Review UNE medical
biochemistry Questions with correct answers
Under |fasting |conditions |(ratio |of |insulin: |glucagon |<1), |elevated |glucagon |will |activate |which |of |the |
following |enzymes? |- |VERIFIED |ANSWER✔✔-hormone |sensitive |lipase
Ketonuria, |hypoglycemia, |and |severe |acidosis |are |prime |diagnostic |indicators |of |the |presentation |of |
type |1 |diabetic |ketoacidosis. |Which |of |the |following |compounds |are |"ketone |bodies" |that |would |be |
elevated |in |serum |of |urine |of |a |patient |in |this |condition? |- |VERIFIED |ANSWER✔✔-D-3-
hydroxybutyrate |and |acetoacetate
What |is |the |purpose |of |cholesterol |esterification |within |the |cell? |(the |conversion |of |cholesterol |to |
cholesteryl |ester)
a. |this |modification |makes |cholesterol |more |soluble |in |the |plasma |membrane
b. |this |modification |does |not |change |the |chemical |properties |of |cholesterol
c. |esterification |is |the |first |step |in |the |synthesis |of |cortisol
d. |esterification |traps |cholesterol |in |the |cell |- |VERIFIED |ANSWER✔✔-esterification |traps |cholesterol |in
|the |cell
An |individual |goes |to |bed |around |8 |pm |and |doesn't |wake |up |until |9 |am |the |next |morning. |During |this
|time, |which |of |the |following |is |the |primary |oxidizable |substrate |in |the |skeletal |muscle?
a. |free |fatty |acids
b. |glycogen
c. |amino |acids
d. |lactate |- |VERIFIED |ANSWER✔✔-free |fatty |acids
A |22-year-old |woman |engaging |in |a |political |protest |goes |on |a |hunger |strike |on |a |prominent |corner |in
|a |city |park. |She |refuses |all |offers |of |food |for |except |for |water |through |the |first |2 |weeks. |Under |these
|conditions |there |is |a |decreased |reliance |on |which |of |the |following |pathways |for |fuel?
a. |β-oxidation
b. |ketogenesis
, c. |gluconeogenesis
d. |lipolysis |- |VERIFIED |ANSWER✔✔-gluconeogenesis
In |reverse |cholesterol |transport |HDL |interacts |with |the |ABCA1 |transporter |to |move |cholesterol |from |
the |cell |to |the |HDL. |This |also |requires |the |activity |of |which |of |the |following |enzyme?
a. |lipoprotein |lipase
b. |cholesteryl |ester |transfer |protein |(CETP)
c. |lecithin |cholesterol |acyltransferase |(LCAT)
d. |LDL |receptor |- |VERIFIED |ANSWER✔✔-lecithin |cholesterol |acyltransferase |(LCAT)
A |16-year-old |woman |presents |to |her |primary |care |physician |for |a |follow |up |visit. |At |her |initial |visit, |3
|months |ago, |her |serum |cholesterol |was |255 |mg/dL |(above |normal). |She |finds |this |very |disappointing |
as |she |started |a |strict |dietary |regime |reducing |all |fats |and |cholesterol, |replacing |them |with |a |high |
carbohydrate |diet. |You |tell |her |that |high |carbohydrate |diets |can |increase |serum |triglyceride |levels |in |
some |individuals. |This |can |be |attributed |in |an |increase |in |the |synthesis |of |which |of |the |following |
lipoproteins?
a. |chylomicrons
b. |VLDL
c. |IDL
d. |HDL
e. |LDL |- |VERIFIED |ANSWER✔✔-VLDL
a |5-year-old |presents |to |her |primary |care |physician. |Her |mother |is |concerned |due |to |persistent |
diarrhea |which |is |worse |when |eating |fatty |foods. |The |child |also |has |some |clinical |signs |of |a |deficiency
|in |fat-soluble |vitamins. |Based |on |this |information |the |child |likely |has |a |deficiency |in |the |ability |to |
synthesize |which |of |the |following |lipoproteins?
a. |chylomicrons
b. |VLDLs
c. |LDLs
d. |HDLs |- |VERIFIED |ANSWER✔✔-chylomicrons
biochemistry Questions with correct answers
Under |fasting |conditions |(ratio |of |insulin: |glucagon |<1), |elevated |glucagon |will |activate |which |of |the |
following |enzymes? |- |VERIFIED |ANSWER✔✔-hormone |sensitive |lipase
Ketonuria, |hypoglycemia, |and |severe |acidosis |are |prime |diagnostic |indicators |of |the |presentation |of |
type |1 |diabetic |ketoacidosis. |Which |of |the |following |compounds |are |"ketone |bodies" |that |would |be |
elevated |in |serum |of |urine |of |a |patient |in |this |condition? |- |VERIFIED |ANSWER✔✔-D-3-
hydroxybutyrate |and |acetoacetate
What |is |the |purpose |of |cholesterol |esterification |within |the |cell? |(the |conversion |of |cholesterol |to |
cholesteryl |ester)
a. |this |modification |makes |cholesterol |more |soluble |in |the |plasma |membrane
b. |this |modification |does |not |change |the |chemical |properties |of |cholesterol
c. |esterification |is |the |first |step |in |the |synthesis |of |cortisol
d. |esterification |traps |cholesterol |in |the |cell |- |VERIFIED |ANSWER✔✔-esterification |traps |cholesterol |in
|the |cell
An |individual |goes |to |bed |around |8 |pm |and |doesn't |wake |up |until |9 |am |the |next |morning. |During |this
|time, |which |of |the |following |is |the |primary |oxidizable |substrate |in |the |skeletal |muscle?
a. |free |fatty |acids
b. |glycogen
c. |amino |acids
d. |lactate |- |VERIFIED |ANSWER✔✔-free |fatty |acids
A |22-year-old |woman |engaging |in |a |political |protest |goes |on |a |hunger |strike |on |a |prominent |corner |in
|a |city |park. |She |refuses |all |offers |of |food |for |except |for |water |through |the |first |2 |weeks. |Under |these
|conditions |there |is |a |decreased |reliance |on |which |of |the |following |pathways |for |fuel?
a. |β-oxidation
b. |ketogenesis
, c. |gluconeogenesis
d. |lipolysis |- |VERIFIED |ANSWER✔✔-gluconeogenesis
In |reverse |cholesterol |transport |HDL |interacts |with |the |ABCA1 |transporter |to |move |cholesterol |from |
the |cell |to |the |HDL. |This |also |requires |the |activity |of |which |of |the |following |enzyme?
a. |lipoprotein |lipase
b. |cholesteryl |ester |transfer |protein |(CETP)
c. |lecithin |cholesterol |acyltransferase |(LCAT)
d. |LDL |receptor |- |VERIFIED |ANSWER✔✔-lecithin |cholesterol |acyltransferase |(LCAT)
A |16-year-old |woman |presents |to |her |primary |care |physician |for |a |follow |up |visit. |At |her |initial |visit, |3
|months |ago, |her |serum |cholesterol |was |255 |mg/dL |(above |normal). |She |finds |this |very |disappointing |
as |she |started |a |strict |dietary |regime |reducing |all |fats |and |cholesterol, |replacing |them |with |a |high |
carbohydrate |diet. |You |tell |her |that |high |carbohydrate |diets |can |increase |serum |triglyceride |levels |in |
some |individuals. |This |can |be |attributed |in |an |increase |in |the |synthesis |of |which |of |the |following |
lipoproteins?
a. |chylomicrons
b. |VLDL
c. |IDL
d. |HDL
e. |LDL |- |VERIFIED |ANSWER✔✔-VLDL
a |5-year-old |presents |to |her |primary |care |physician. |Her |mother |is |concerned |due |to |persistent |
diarrhea |which |is |worse |when |eating |fatty |foods. |The |child |also |has |some |clinical |signs |of |a |deficiency
|in |fat-soluble |vitamins. |Based |on |this |information |the |child |likely |has |a |deficiency |in |the |ability |to |
synthesize |which |of |the |following |lipoproteins?
a. |chylomicrons
b. |VLDLs
c. |LDLs
d. |HDLs |- |VERIFIED |ANSWER✔✔-chylomicrons
