Medical biochemistry final exam questions
with correct answers
Competitive |inhibition |- |VERIFIED |ANSWER✔✔-competes |w/ |substrate |for |binding |to |the |active |site |
but |does |not |effect |catalysis |
- |Vmax |= |no |change
- |Km |= |increases |
- |LWB= |lines |intersect |at |y-axis
Uncompetitive |inhibition |- |VERIFIED |ANSWER✔✔-only |binds |to |the |ES |complex |and |does |not |affect |
substrate |binding |but |inhibits |catalytic |functions |
- |Vmax |= |decrease |
-Km= |decrease |
- |no |change |in |km/Vmax |
-LWB |= |lines |are |parallel
noncompetitve |inhibitor |- |VERIFIED |ANSWER✔✔-- |Vmax |= |decrease |
-Km |= |no |change
Free |energy |change |- |VERIFIED |ANSWER✔✔-(delta |G |) |the |amount |of |free |energy |released |(-DeltaG) |
or |absorbed |(+ |Delta |G) |in |a |reaction |at |constant |temperature |and |pressure |
- |Exergonic |= |- |Delta |G |
- |endergonic |= |+ |Delta |G
Enthalpy |(H) |- |VERIFIED |ANSWER✔✔-The |heat |content |of |a |system |at |constant |pressure
Entropy |(S) |- |VERIFIED |ANSWER✔✔-the |extent |of |randomness |or |disorder |in |a |system
When |Delta |H |and |Delta |S |are |both |negative |the |reaction |. |. |. |- |VERIFIED |ANSWER✔✔-enthalpically |
favored |but |entropically |opposed, |it |is |spontaneous |only |at |temperatures |below |T= |deltaH/deltaS
with correct answers
Competitive |inhibition |- |VERIFIED |ANSWER✔✔-competes |w/ |substrate |for |binding |to |the |active |site |
but |does |not |effect |catalysis |
- |Vmax |= |no |change
- |Km |= |increases |
- |LWB= |lines |intersect |at |y-axis
Uncompetitive |inhibition |- |VERIFIED |ANSWER✔✔-only |binds |to |the |ES |complex |and |does |not |affect |
substrate |binding |but |inhibits |catalytic |functions |
- |Vmax |= |decrease |
-Km= |decrease |
- |no |change |in |km/Vmax |
-LWB |= |lines |are |parallel
noncompetitve |inhibitor |- |VERIFIED |ANSWER✔✔-- |Vmax |= |decrease |
-Km |= |no |change
Free |energy |change |- |VERIFIED |ANSWER✔✔-(delta |G |) |the |amount |of |free |energy |released |(-DeltaG) |
or |absorbed |(+ |Delta |G) |in |a |reaction |at |constant |temperature |and |pressure |
- |Exergonic |= |- |Delta |G |
- |endergonic |= |+ |Delta |G
Enthalpy |(H) |- |VERIFIED |ANSWER✔✔-The |heat |content |of |a |system |at |constant |pressure
Entropy |(S) |- |VERIFIED |ANSWER✔✔-the |extent |of |randomness |or |disorder |in |a |system
When |Delta |H |and |Delta |S |are |both |negative |the |reaction |. |. |. |- |VERIFIED |ANSWER✔✔-enthalpically |
favored |but |entropically |opposed, |it |is |spontaneous |only |at |temperatures |below |T= |deltaH/deltaS