CHAMBERLAIN NR507 MIDTERM
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Terms in this set (63)
, - "Allergic reaction"
- Mediated by IgE.
- Inflammation d/t mast cell
degranulation.
Type 1 - Hay fever, hives (uticaria).
Hypersensitivity - Local s/s: itching, rash.
Reaction - Systemic: wheezing.
- Severe, systemic reaction: anaphylaxis:
hypotension, severe
bronchoconstriction.
- Main tx: epinephrine.
- Cytotoxic reaction; tissue specific
- Macrophages are the primary
effectors cells involved
- Causes tissue damage or alters
function
Type 2 - Examples: 1) Grave's disease- example
Hypersensitivity of altering thyroid function, doesn't
Reaction destroy thyroid tissue. 2) ABO
incompatibility- example of cell/tissue
damage; severe transfusion reaction
occurs & the transfused erythrocytes
are destroyed by agglutination or
complement-mediated lysis.
, - Type 2: organ specific; antibody binds
to the antigen on the cell surface.
Difference
- Type 3: not organ specific; antibody
between type 2 &
binds to soluble antigen outside the cell
3 hypersensitivity
surface that was released into the
reactions
blood or body fluids, and the complex
is then deposited in the tissues.
- Immune complex
- Antigen-antibody complex deposited
in the tissues
Type 3 - Neutrophils are the primary effector
Hypersensitivity cell
Reaction - Causes autoimmune diseases
- Examples: rheumatoid arthritis ( joints),
systemic lupus erythematosus (SLE,
organs)
EXAM GUIDE /COMPREHENSIVE
STUDY GUIDE ACTUAL LATEST
VERSION /QUESTIONS AND
CORRECT ANSWERS / A GRADE
SCORE SOLUTION.
Save
Terms in this set (63)
, - "Allergic reaction"
- Mediated by IgE.
- Inflammation d/t mast cell
degranulation.
Type 1 - Hay fever, hives (uticaria).
Hypersensitivity - Local s/s: itching, rash.
Reaction - Systemic: wheezing.
- Severe, systemic reaction: anaphylaxis:
hypotension, severe
bronchoconstriction.
- Main tx: epinephrine.
- Cytotoxic reaction; tissue specific
- Macrophages are the primary
effectors cells involved
- Causes tissue damage or alters
function
Type 2 - Examples: 1) Grave's disease- example
Hypersensitivity of altering thyroid function, doesn't
Reaction destroy thyroid tissue. 2) ABO
incompatibility- example of cell/tissue
damage; severe transfusion reaction
occurs & the transfused erythrocytes
are destroyed by agglutination or
complement-mediated lysis.
, - Type 2: organ specific; antibody binds
to the antigen on the cell surface.
Difference
- Type 3: not organ specific; antibody
between type 2 &
binds to soluble antigen outside the cell
3 hypersensitivity
surface that was released into the
reactions
blood or body fluids, and the complex
is then deposited in the tissues.
- Immune complex
- Antigen-antibody complex deposited
in the tissues
Type 3 - Neutrophils are the primary effector
Hypersensitivity cell
Reaction - Causes autoimmune diseases
- Examples: rheumatoid arthritis ( joints),
systemic lupus erythematosus (SLE,
organs)
