PATHOLOGY ASSISTANT ASCP EXAM (actual 2025/2026)
QUESTIONS AND verified ANSWERS
Proteus vulgaris in kidney - ---Answers----Bacteria that
causes ammonium magnesium phosphate stones.
Staghorn (struvite) calculi
Alkaline urine
Kayser-Fleischer Ring - ---Answers----Wilson's disease
Build up of copper (decrease in serum ceruloplasmin)
Mallory Bodies - ---Answers----Cytoplasm of liver in
alcoholics
Negri bodies - ---Answers----Nerve cells of Rabies
Arcus Senilis - ---Answers----White, gray, blue opaque ring
in corneal margin
Present at birth and elderly
Hypercholeserolemia deposits
Gardner Syndrome - ---Answers----Autosomal dominate
Numerous adenomatous polyps, osteomas and soft tissue
tumors
Familial Polyposis - ---Answers----Autosomal dominate
,Adenomatous polyps, 100% malignant transformation
Turcot Syndrome - ---Answers----Adenomatous polyps
CNS tumors
Cronkhite-Canada Syndrome - ---Answers----Non-Inherited
Multiple polyps, idiopathic
2/3's Japanese men
Budd-Chiari Syndrome - ---Answers----Pregnant women,
Polycythemiavera, Hepatocellular carcinoma
Ascites, abd pain, hepatomegaly, elevated liver enzymes,
hepatic vein thrombotic occlusion
Arnold Chiari Malformation - ---Answers----Downward
displacement of cerebellar tonsils and medulla through
foreman magnum (displaced brain tissue atrophy).
Hydocephalus (CSF) obstructed
Thoracolumbar meningomyelocele
Oncocytomas - ---Answers----Large eosinophilic cells that
have small round nuclei and large nucleoli with numerous
mitochondria
Cystitis - ---Answers----Bladder inflammation
Hematuria, pyuria, no white cell casts
,Ureteritis cystica - ---Answers----Chronic inflammation of
ureters
mucosal cysts (0.1-0.5 cm)
Polypoid Cystitis - ---Answers----Longterm catheters,
mucosal bulges (not mistaken for papillary)
Malacoplakia - ---Answers----Chronic, bacterial, soft, yellow,
raised plaques up to 4 cm
Large foamy macrophages with scant giant cells and
lymphocytes
Interstitial Cystitis - ---Answers----Submucosal
hemorrhages, localized ulceration (Hunner ulcer),
inflammation and fibrosis of all bladder walls
Targetoid Michaelis-Gutmann bodies
E. coli
Identical lesions occur in other organs of the body
Diabetes Melitus Type 1 - ---Answers----Failure of insulin
synthesis
Increased thirst, extreme hunger and recent weight loss
Sarcoma Botryoides - ---Answers----0-5 yrs.
, Multiple polypoid masses on vulva project into the vagina
"bunches of grapes"
Variant of rhabdomyosarcoma
Prolactinoma - ---Answers----Most common anterior
pituitary tumor in women.
Causes anterior pituitary hyper function, amenorrhea and
galactorrhea, infertility
Chromophobic staining
Corticotropic Adenoma - ---Answers----Cushings
Somatotropic Adenoma - ---Answers----Giantism in children
Acromegaly in adults
Adamantinoma
Craniopharyngioma - ---Answers----Benign, not true pituitary
tumor
Remnants of Rathke pouch
Similar to ameloblastoma of the jaw, resembles embryonic
tooth bud enamel organ, cystic expands to papillary
projections, x-ray to see calcifications
Phimosis - ---Answers----Can't pull foreskin back over
glands penis
QUESTIONS AND verified ANSWERS
Proteus vulgaris in kidney - ---Answers----Bacteria that
causes ammonium magnesium phosphate stones.
Staghorn (struvite) calculi
Alkaline urine
Kayser-Fleischer Ring - ---Answers----Wilson's disease
Build up of copper (decrease in serum ceruloplasmin)
Mallory Bodies - ---Answers----Cytoplasm of liver in
alcoholics
Negri bodies - ---Answers----Nerve cells of Rabies
Arcus Senilis - ---Answers----White, gray, blue opaque ring
in corneal margin
Present at birth and elderly
Hypercholeserolemia deposits
Gardner Syndrome - ---Answers----Autosomal dominate
Numerous adenomatous polyps, osteomas and soft tissue
tumors
Familial Polyposis - ---Answers----Autosomal dominate
,Adenomatous polyps, 100% malignant transformation
Turcot Syndrome - ---Answers----Adenomatous polyps
CNS tumors
Cronkhite-Canada Syndrome - ---Answers----Non-Inherited
Multiple polyps, idiopathic
2/3's Japanese men
Budd-Chiari Syndrome - ---Answers----Pregnant women,
Polycythemiavera, Hepatocellular carcinoma
Ascites, abd pain, hepatomegaly, elevated liver enzymes,
hepatic vein thrombotic occlusion
Arnold Chiari Malformation - ---Answers----Downward
displacement of cerebellar tonsils and medulla through
foreman magnum (displaced brain tissue atrophy).
Hydocephalus (CSF) obstructed
Thoracolumbar meningomyelocele
Oncocytomas - ---Answers----Large eosinophilic cells that
have small round nuclei and large nucleoli with numerous
mitochondria
Cystitis - ---Answers----Bladder inflammation
Hematuria, pyuria, no white cell casts
,Ureteritis cystica - ---Answers----Chronic inflammation of
ureters
mucosal cysts (0.1-0.5 cm)
Polypoid Cystitis - ---Answers----Longterm catheters,
mucosal bulges (not mistaken for papillary)
Malacoplakia - ---Answers----Chronic, bacterial, soft, yellow,
raised plaques up to 4 cm
Large foamy macrophages with scant giant cells and
lymphocytes
Interstitial Cystitis - ---Answers----Submucosal
hemorrhages, localized ulceration (Hunner ulcer),
inflammation and fibrosis of all bladder walls
Targetoid Michaelis-Gutmann bodies
E. coli
Identical lesions occur in other organs of the body
Diabetes Melitus Type 1 - ---Answers----Failure of insulin
synthesis
Increased thirst, extreme hunger and recent weight loss
Sarcoma Botryoides - ---Answers----0-5 yrs.
, Multiple polypoid masses on vulva project into the vagina
"bunches of grapes"
Variant of rhabdomyosarcoma
Prolactinoma - ---Answers----Most common anterior
pituitary tumor in women.
Causes anterior pituitary hyper function, amenorrhea and
galactorrhea, infertility
Chromophobic staining
Corticotropic Adenoma - ---Answers----Cushings
Somatotropic Adenoma - ---Answers----Giantism in children
Acromegaly in adults
Adamantinoma
Craniopharyngioma - ---Answers----Benign, not true pituitary
tumor
Remnants of Rathke pouch
Similar to ameloblastoma of the jaw, resembles embryonic
tooth bud enamel organ, cystic expands to papillary
projections, x-ray to see calcifications
Phimosis - ---Answers----Can't pull foreskin back over
glands penis
