Peptic Ulcer Disease (PUD) 2025
Questions and Answers 100% Pass
PUD is caused by... - ✔✔the imbalance between gastric mucosal defenses and
antagonistic factors such as H. pylori, NSAIDs, and secretions including gastric acid
and pepsin.
The five groups of medications used in PUD managements are? - ✔✔- Antibiotics
(amoxicillin, bismuth, clarithromycin, metornidazole, tetracycline)
- Antisecretory Agents: Histamine 2 receptor antagonists (tidine) and Proton Pump
Inhbitors (prazole)
- Mucosal Protectants (sucralfate)
- Antacids
- Prostaglandin E Analog (misoprostol)
5 Antibiotics - ✔✔Amoxicillin
Bismuth
Clarithromycin
Metronidazole
Tetracycline
Antibiotics ____ further development of PUD and ____ or ____ the disease process.
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, They ____ ____ and ____ the growth of H. Pylori. - ✔✔- INHIBIT, stop or alter
- Break down and Decrease
Expected Pharmacologic Actions of Antibiotics? - ✔✔Eradication of H Pylori
Therapy should include what for Antibiotics (amoxicillin, bismuth, clarithromycin,
metornidazole, tetracycline) ? - ✔✔a combination of 2-3 antibiotics for 14 days to
increase effectiveness and to minimize the development of drug resistance
In regards to antibiotics (amoxicillin, bismuth, clarithromycin, metornidazole,
tetracycline) advise patients of.... - ✔✔-decreased effectiveness of birth control
- nausea and diarrhea are common
- take the full course of medications as prescribed
What drugs are classified as Histamine 2 receptor antagonists, PUD Therapy? What
is the common ending? - ✔✔-Ranitidine, cimetidine, famotidine, nizatidine.
- TIDINE
Histamine 2 receptor antagonists, PUD Therapy, are most commonly found where? -
✔✔OTC
Mechanism of Action for Histamine 2 receptor antagonists, PUD Therapy,? -
✔✔suppress the secretion of gastric acid by selectively blocking H2 receptors in
parietal cells lining the stomach
Histamine 2 receptor antagonists, PUD Therapy, TIDINE's, are used for? and can be
used in conjunction with? - ✔✔GUD/PUD/GERD and are used in conjunction with
antibiotics to treat ulcers caused by H pylori.
Histamine 2 receptor antagonists, PUD Therapy, "tidine's" promote ____ ____ and
suppress the ____ ____. - ✔✔promotes bacterial growth and suppress the gastric acid
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