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SARAH MICHELLE LIVE REVIEW STUDY GUIDE

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SARAH MICHELLE LIVE REVIEW STUDY GUIDE
(COMPLETE)
What is the screening tool for the thyroid? - ANS-TSH Level

What is the normal range for TSH? - ANS-0.5-5.0

When do you order a full thyroid profile? - ANS-If thyroid screening of TSH comes back
abnormal, then we will reorder TSH and T3, T4.

What disorder demonstrates a low TSH level and high T3 and T4 levels? - ANS-
Hyperthyroidism

What disorder demonstrates a high TSH level and low T3 and T4 levels? - ANS-
Hypothyroidism

What medication is used to treat hypothyroidism? - ANS-Levothyroxine (Synthroid)

What dose of Synthroid do you want to start your patient on? - ANS-If patient is elderly
or if they have a significant cardiac history then we are going to start at a lower dose of
12.5-25 mcg po daily.
In a normal healthy patient, we will start at 25-50 mcg po daily.

After initiation of medication for treatment of hypothyroidism, when do you recheck TSH
level? - ANS-6-8 weeks

When TSH level is stabilized, how often do you recheck their level? - ANS-Every 6-12
months

What is the go to medication for treatment of hyperthyroidism? - ANS-Tapazole and
PTU

How do you manage treatment for hyperthyroidism in a pregnant patient? - ANS-We
need to use PTU instead if they are in their first trimester. After first trimester, then they
can be switched to tapazole.

What medication class is used to treat symptoms of hyperthyroidism? - ANS-Beta-
blockers- these help manage tachycardia and palpitations

What are 2 other treatments for the hyperthyroidism? - ANS-Thyroidectomy and
radioactive iodine

What labs are used to measure and evaluate kidney function? - ANS-GFR, BUN,
Creatinine

,What lab value is most accurate description of kidney function? - ANS-GFR- this is
going to tell us how the kidneys are filtering the blood and how well they are removing
waste.

What is a normal GFR value? - ANS->90

What GFR value indicates an absolute need to start a patient on dialysis? - ANS-<15-
this means that patient is in CKD stage 5

What is the second most important lab value to measure kidney function? - ANS-
Creatinine

What is creatinine? - ANS-A waste product in the blood. If your kidneys are functioning
properly, then this waste product is removed by your kidneys. When kidney function
decreases, your creatinine level starts to rise.

What is a normal creatine value? - ANS-Around 1

Why is BUN least telling for kidney function? - ANS-Blood urea nitrogen is a normal
waste product when your body breaks down urea. However, this is not specific to the
kidneys. It can also indicate liver issues.

What is a normal BUN level? - ANS-10-20

With which first-line BP medication do we want to check the BUN/Cr? - ANS-ACE
Inhibitors

What finding on a UA id indicative of true kidney damage? - ANS-Casts- WBC or RBC
casts always need to be referred out

When do we screen for microalbumin in the urine? - ANS-We're always going to screen
when DM and HTN is first diagnosed.

What are the most common causes of CKD? - ANS-HTN and DM

Why is it important to perform early screening for microalbumin in the urine? - ANS-
Patients who have mild kidney damage do not have symptoms, this screening will
ideally identify damage early and prevent progression.

What stage of CKD do patients show true symptoms? - ANS-Stage 3 or worse

How often are we screening for micro albumin? - ANS-Bare minimum is going to be
annually for patients with DM or HTN or both.

What is the normal range of microalbumin? - ANS-< 30

,What is the most common symptom of all anemias? - ANS-Fatigue

What is a normal hemoglobin level? - ANS-12-18
Women are on the lower end, and men are on the higher end

What is a normal hemoglobin to hematocrit ratio? - ANS-3 to 1
36-54%

What does MCV stand for? - ANS-mean corpuscular volume

What is a normal MCV? - ANS-80-100

What does low MCV indicate? - ANS-Microcytic anemias

What is the most common microcytic anemia? - ANS-Iron deficiency anemia

What is the biggest risk faction for the development of IDA is int he first year of life? -
ANS-The ingestion of cow's milk

What does high MCV levels indicate? - ANS-Microcytic anemia

What are the most common microcytic anemias? - ANS-B12 and folate

What symptoms are common with B12 deficiency anemia? - ANS-Neuro symptoms- the
most common symptom is parasthesia

What surgery typically leads to B12 deficiency anemia? - ANS-Gastrectomy patients-
who have part of their stomach removed

Why do gastrectomy patients typically have B12 deficiency anemia? - ANS-In order for
B12 to be absorbed, it needs to be able to combine with intrinsic factor, which is
produced in the stomach. If we remove a large portion of the stomach then we lose a lot
of that intrinsic factor.

What diabetes medication used long term can also lead to B12 deficiency? - ANS-
Metformin

What is an abnormal lead level? - ANS->5, ideally no lead should be within the body

What kind of symptoms may lead intoxication lead to? - ANS-Cognitive delays and
behavioral problems

What are the 3 microcytic anemias? - ANS-LIT
Lead
Iron
Thalassemia

, What are the 2 macrocytic anemias? - ANS-FAB
Folate and B12

What are the components of a lipid profile? - ANS-Total cholesterol
HDl
LDL
Triglycerides

What's a normal total cholesterol level? - ANS-<200

What is a normal HDL level? - ANS-40-60, the higher the better

What is a normal LDL level? - ANS-<100

What is a normal triglyceride level? - ANS-<150

How often should you be ordering a standard limpid profile on a patient? - ANS-Every 5
years unless they are having symptoms, risk factors, on treatment, etc.

What is LDL? - ANS-Bad cholesterol, it is our major culprit in atherosclerosis in clogging
up those arteries.

What is HDL? - ANS-Good cholesterol, it is cardio protective and helps remove excess
cholesterol from the body.

What are some factors that impact our total cholesterol? - ANS-Smoking, diet, weight,
and physical activity

What does triglycerides assist in assessing? - ANS-Insulin resistance and your true
dietary intake

If triglycerides get >500 then patient will be at really high risk for what? - ANS-
Pancreatitis

What is the first line treatment for abnormal lipid levels? - ANS-HMG-CoA Reductase
Inhibitors- Statin drugs

What if a patient is having increased muscle pain on a statin, what is worst case
scenario? - ANS-Rhabdomyolysis

What lab value will assess for rhabdomyolysis? - ANS-CK level

How high is a CK level going to be in rhabdo? - ANS-5 times the normal limit

What can rhabdomyolysis lead to? - ANS-Renal failure

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